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• W3015012616 startingPage "783" @default.
• W3015012616 abstract "Multiple sclerosis (MS) is a common, severe neurological disease that affects millions of people worldwide. Nevertheless, the actual cause of MS remains unknown. Smoking has been studied with respect to MS development and progression. The objectives of this review were to examine the relationship between smoking and MS and to understand the possible molecular mechanisms underlying the association. PubMed was searched for articles related to the study topic published between 2012 and 2020 using the search terms multiple sclerosis, smoking, risk factors, cigarettes, and molecular mechanisms. Studies show a significant relationship between smoking and the risk of MS. Furthermore, smoking has been linked to the progression of MS at the patient and population levels. However, the underlying mechanism remains to be explored in further studies; researchers still disagree on how the relationship between smoking and MS arises in different populations. Evidence from randomized controlled trials, systematic reviews, and epidemiological studies shows that smokers have a higher risk of developing MS and experiencing related adverse symptoms and complications." @default.
• W3015012616 created "2020-04-10" @default.
• W3015012616 creator A5017996365 @default.
• W3015012616 date "2020-07-01" @default.
• W3015012616 modified "2023-10-09" @default.
• W3015012616 title "Multiple Sclerosis and Smoking" @default.
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• W3015012616 doi "https://doi.org/10.1016/j.amjmed.2020.03.008" @default.
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• W3015012616 hasPublicationYear "2020" @default.
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