FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3015052923> ?p ?o ?g. }

• W3015052923 endingPage "802" @default.
• W3015052923 startingPage "796" @default.
• W3015052923 abstract "BACKGROUND Post-traumatic stress disorder is a severe psychobiological disorder associated with hyperactivity of the amygdala, particularly on the right side. Highly selective laser ablation of the amygdalohippocampal complex is an effective neurosurgical treatment for medically refractory medial temporal lobe epilepsy that minimizes neurocognitive deficits relative to traditional open surgery. OBJECTIVE To examine the impact of amygdalohippocampotomy upon symptoms and biomarkers of post-traumatic stress disorder. METHODS Two patients with well-documented chronic post-traumatic stress disorder who subsequently developed late-onset epilepsy underwent unilateral laser amygdalohippocampotomy. Prospective clinical and neuropsychological measurements were collected in patient 1. Additional prospective measurements of symptoms and biomarkers were collected pre- and post-surgery in patient 2. RESULTS After laser ablation targeting the nondominant (right) amygdala, both patients experienced not only reduced seizures, but also profoundly abated post-traumatic stress symptoms. Prospective evaluation of biomarkers in patient 2 showed robust improvements in hyperarousal symptoms, fear potentiation of the startle reflex, brain functional magnetic resonance imaging responses to fear-inducing stimuli, and emotional declarative memory. CONCLUSION These observations support the emerging hypothesis that the right amygdala particularly perpetuates the signs and symptoms of post-traumatic stress disorder and suggests that focal unilateral amydalohippocampotomy can provide therapeutic benefit." @default.
• W3015052923 created "2020-04-10" @default.
• W3015052923 creator A5015982658 @default.
• W3015052923 creator A5016572077 @default.
• W3015052923 creator A5023826003 @default.
• W3015052923 creator A5024835315 @default.
• W3015052923 creator A5037043280 @default.
• W3015052923 creator A5043243224 @default.
• W3015052923 creator A5048174176 @default.
• W3015052923 creator A5052883633 @default.
• W3015052923 creator A5075257930 @default.
• W3015052923 creator A5080082654 @default.
• W3015052923 date "2020-04-07" @default.
• W3015052923 modified "2023-10-16" @default.
• W3015052923 title "Case Series: Unilateral Amygdala Ablation Ameliorates Post-Traumatic Stress Disorder Symptoms and Biomarkers" @default.
• W3015052923 cites W1199377154 @default.
• W3015052923 cites W2012819349 @default.
• W3015052923 cites W2040626393 @default.
• W3015052923 cites W2049070000 @default.
• W3015052923 cites W2081273690 @default.
• W3015052923 cites W2099246727 @default.
• W3015052923 cites W2103881507 @default.
• W3015052923 cites W2115084515 @default.
• W3015052923 cites W2118826874 @default.
• W3015052923 cites W2137084838 @default.
• W3015052923 cites W2143959560 @default.
• W3015052923 cites W2148616431 @default.
• W3015052923 cites W2160157454 @default.
• W3015052923 cites W2520501751 @default.
• W3015052923 cites W2595446788 @default.
• W3015052923 cites W2739325771 @default.
• W3015052923 cites W2770072520 @default.
• W3015052923 cites W2789679712 @default.
• W3015052923 doi "https://doi.org/10.1093/neuros/nyaa051" @default.
• W3015052923 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8046583" @default.
• W3015052923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33611569" @default.
• W3015052923 hasPublicationYear "2020" @default.
• W3015052923 type Work @default.
• W3015052923 sameAs 3015052923 @default.
• W3015052923 citedByCount "17" @default.
• W3015052923 countsByYear W30150529232020 @default.
• W3015052923 countsByYear W30150529232021 @default.
• W3015052923 countsByYear W30150529232022 @default.
• W3015052923 countsByYear W30150529232023 @default.
• W3015052923 crossrefType "journal-article" @default.
• W3015052923 hasAuthorship W3015052923A5015982658 @default.
• W3015052923 hasAuthorship W3015052923A5016572077 @default.
• W3015052923 hasAuthorship W3015052923A5023826003 @default.
• W3015052923 hasAuthorship W3015052923A5024835315 @default.
• W3015052923 hasAuthorship W3015052923A5037043280 @default.
• W3015052923 hasAuthorship W3015052923A5043243224 @default.
• W3015052923 hasAuthorship W3015052923A5048174176 @default.
• W3015052923 hasAuthorship W3015052923A5052883633 @default.
• W3015052923 hasAuthorship W3015052923A5075257930 @default.
• W3015052923 hasAuthorship W3015052923A5080082654 @default.
• W3015052923 hasBestOaLocation W30150529232 @default.
• W3015052923 hasConcept C118552586 @default.
• W3015052923 hasConcept C126322002 @default.
• W3015052923 hasConcept C126838900 @default.
• W3015052923 hasConcept C14216870 @default.
• W3015052923 hasConcept C143409427 @default.
• W3015052923 hasConcept C169900460 @default.
• W3015052923 hasConcept C172467417 @default.
• W3015052923 hasConcept C188816634 @default.
• W3015052923 hasConcept C2778159538 @default.
• W3015052923 hasConcept C2778615406 @default.
• W3015052923 hasConcept C2778902805 @default.
• W3015052923 hasConcept C2779144063 @default.
• W3015052923 hasConcept C2781017439 @default.
• W3015052923 hasConcept C42219234 @default.
• W3015052923 hasConcept C71924100 @default.
• W3015052923 hasConceptScore W3015052923C118552586 @default.
• W3015052923 hasConceptScore W3015052923C126322002 @default.
• W3015052923 hasConceptScore W3015052923C126838900 @default.
• W3015052923 hasConceptScore W3015052923C14216870 @default.
• W3015052923 hasConceptScore W3015052923C143409427 @default.
• W3015052923 hasConceptScore W3015052923C169900460 @default.
• W3015052923 hasConceptScore W3015052923C172467417 @default.
• W3015052923 hasConceptScore W3015052923C188816634 @default.
• W3015052923 hasConceptScore W3015052923C2778159538 @default.
• W3015052923 hasConceptScore W3015052923C2778615406 @default.
• W3015052923 hasConceptScore W3015052923C2778902805 @default.
• W3015052923 hasConceptScore W3015052923C2779144063 @default.
• W3015052923 hasConceptScore W3015052923C2781017439 @default.
• W3015052923 hasConceptScore W3015052923C42219234 @default.
• W3015052923 hasConceptScore W3015052923C71924100 @default.
• W3015052923 hasIssue "4" @default.
• W3015052923 hasLocation W30150529231 @default.
• W3015052923 hasLocation W30150529232 @default.
• W3015052923 hasOpenAccess W3015052923 @default.
• W3015052923 hasPrimaryLocation W30150529231 @default.
• W3015052923 hasRelatedWork W2123461383 @default.
• W3015052923 hasRelatedWork W2277826541 @default.
• W3015052923 hasRelatedWork W2282014563 @default.
• W3015052923 hasRelatedWork W2290211399 @default.
• W3015052923 hasRelatedWork W2315917474 @default.
• W3015052923 hasRelatedWork W2499256430 @default.
• W3015052923 hasRelatedWork W2560983496 @default.

• next