Matches in SemOpenAlex for { <https://semopenalex.org/work/W3015364209> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W3015364209 abstract "We study the problem of finding the optimal dosage in early stage clinical trials through the multi-armed bandit lens. We advocate the use of the Thompson Sampling principle, a flexible algorithm that can accommodate different types of monotonicity assumptions on the toxicity and efficacy of the doses. For the simplest version of Thompson Sampling, based on a uniform prior distribution for each dose, we provide finite-time upper bounds on the number of sub-optimal dose selections, which is unprecedented for dose-finding algorithms. Through a large simulation study, we then show that variants of Thompson Sampling based on more sophisticated prior distributions outperform state-of-the-art dose identification algorithms in different types of dose-finding studies that occur in phase I or phase I/II trials." @default.
- W3015364209 created "2020-04-17" @default.
- W3015364209 creator A5032679355 @default.
- W3015364209 creator A5082071129 @default.
- W3015364209 creator A5083219425 @default.
- W3015364209 date "2021-01-01" @default.
- W3015364209 modified "2023-10-16" @default.
- W3015364209 title "On Multi-Armed Bandit Designs for Dose-Finding Trials" @default.
- W3015364209 cites W1911551976 @default.
- W3015364209 cites W1998498767 @default.
- W3015364209 cites W2007276247 @default.
- W3015364209 cites W2036803464 @default.
- W3015364209 cites W2039522160 @default.
- W3015364209 cites W2051778548 @default.
- W3015364209 cites W2058011043 @default.
- W3015364209 cites W2071341777 @default.
- W3015364209 cites W2076108528 @default.
- W3015364209 cites W2094615848 @default.
- W3015364209 cites W2097166956 @default.
- W3015364209 cites W2099201756 @default.
- W3015364209 cites W2108738385 @default.
- W3015364209 cites W2108794978 @default.
- W3015364209 cites W2112420033 @default.
- W3015364209 cites W2126559945 @default.
- W3015364209 cites W2135234083 @default.
- W3015364209 cites W2141645258 @default.
- W3015364209 cites W2142971854 @default.
- W3015364209 cites W2149636226 @default.
- W3015364209 cites W2166253248 @default.
- W3015364209 cites W2168405694 @default.
- W3015364209 cites W2275089335 @default.
- W3015364209 cites W2311178916 @default.
- W3015364209 cites W2322444413 @default.
- W3015364209 cites W2491105136 @default.
- W3015364209 cites W2742246555 @default.
- W3015364209 cites W2769648743 @default.
- W3015364209 cites W2791498037 @default.
- W3015364209 cites W2951579369 @default.
- W3015364209 cites W3100329718 @default.
- W3015364209 cites W3103604572 @default.
- W3015364209 cites W651652324 @default.
- W3015364209 cites W2463351286 @default.
- W3015364209 hasPublicationYear "2021" @default.
- W3015364209 type Work @default.
- W3015364209 sameAs 3015364209 @default.
- W3015364209 citedByCount "0" @default.
- W3015364209 crossrefType "journal-article" @default.
- W3015364209 hasAuthorship W3015364209A5032679355 @default.
- W3015364209 hasAuthorship W3015364209A5082071129 @default.
- W3015364209 hasAuthorship W3015364209A5083219425 @default.
- W3015364209 hasBestOaLocation W30153642091 @default.
- W3015364209 hasConcept C41008148 @default.
- W3015364209 hasConceptScore W3015364209C41008148 @default.
- W3015364209 hasLocation W30153642091 @default.
- W3015364209 hasLocation W30153642092 @default.
- W3015364209 hasOpenAccess W3015364209 @default.
- W3015364209 hasPrimaryLocation W30153642091 @default.
- W3015364209 hasRelatedWork W1596801655 @default.
- W3015364209 hasRelatedWork W2130043461 @default.
- W3015364209 hasRelatedWork W2350741829 @default.
- W3015364209 hasRelatedWork W2358668433 @default.
- W3015364209 hasRelatedWork W2376932109 @default.
- W3015364209 hasRelatedWork W2382290278 @default.
- W3015364209 hasRelatedWork W2390279801 @default.
- W3015364209 hasRelatedWork W2748952813 @default.
- W3015364209 hasRelatedWork W2899084033 @default.
- W3015364209 hasRelatedWork W2530322880 @default.
- W3015364209 isParatext "false" @default.
- W3015364209 isRetracted "false" @default.
- W3015364209 magId "3015364209" @default.
- W3015364209 workType "article" @default.