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• W3015377980 abstract "Abstract Value coding of external stimuli in general, and odor valence in particular, is crucial for survival. In flies, odor valence is thought to be coded by two types of neurons: mushroom body output neurons (MBONs) and lateral horn (LH) neurons. MBONs are classified as neurons that promote either attraction or aversion, but not both, and they are dynamically activated by upstream neurons. This dynamic activation updates the valence values. In contrast, LH neurons receive scaled, but non-dynamic, input from their upstream neurons. It remains unclear how such a non-dynamic system generates differential valence values. Recently, PD2a1/b1 LH neurons were demonstrated to promote approach behavior at low odor concentration in starved flies. Here, we demonstrate that at high odor concentrations, these same neurons contribute to avoidance in satiated flies. The contribution of PD2a1/b1 LH neurons to aversion is context dependent. It is diminished in starved flies, although PD2a1/b1 neural activity remains unchanged, and at lower odor concentration. In addition, PD2a1/b1 aversive effect develops over time. Thus, our results indicate that, even though PD2a1/b1 LH neurons transmit hard-wired output, their effect on valence can change. Taken together, we suggest that the valence model described for MBONs does not hold for LH neurons." @default.
• W3015377980 created "2020-04-17" @default.
• W3015377980 creator A5016973132 @default.
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• W3015377980 creator A5055023434 @default.
• W3015377980 creator A5065951809 @default.
• W3015377980 creator A5082882496 @default.
• W3015377980 date "2020-04-09" @default.
• W3015377980 modified "2023-10-16" @default.
• W3015377980 title "Differential Role for a Defined Lateral Horn Neuron Subset in Naïve Odor Valence in Drosophila" @default.
• W3015377980 cites W1968358311 @default.
• W3015377980 cites W1969371674 @default.
• W3015377980 cites W1969837542 @default.
• W3015377980 cites W1972201383 @default.
• W3015377980 cites W1973078582 @default.
• W3015377980 cites W1974214965 @default.
• W3015377980 cites W1975881038 @default.
• W3015377980 cites W1977477867 @default.
• W3015377980 cites W1979992706 @default.
• W3015377980 cites W1981922832 @default.
• W3015377980 cites W1986629988 @default.
• W3015377980 cites W1989868131 @default.
• W3015377980 cites W1989965174 @default.
• W3015377980 cites W1991444978 @default.
• W3015377980 cites W1995719700 @default.
• W3015377980 cites W1998105194 @default.
• W3015377980 cites W1999401580 @default.
• W3015377980 cites W1999985543 @default.
• W3015377980 cites W2001560475 @default.
• W3015377980 cites W2002737851 @default.
• W3015377980 cites W2006229889 @default.
• W3015377980 cites W2006372098 @default.
• W3015377980 cites W2007209883 @default.
• W3015377980 cites W2010475409 @default.
• W3015377980 cites W2012756610 @default.
• W3015377980 cites W2022954501 @default.
• W3015377980 cites W2030092068 @default.
• W3015377980 cites W2036335143 @default.
• W3015377980 cites W2039158671 @default.
• W3015377980 cites W2039569931 @default.
• W3015377980 cites W2042969699 @default.
• W3015377980 cites W2047234954 @default.
• W3015377980 cites W2050429501 @default.
• W3015377980 cites W2052289243 @default.
• W3015377980 cites W2056419186 @default.
• W3015377980 cites W2057825122 @default.
• W3015377980 cites W2063699128 @default.
• W3015377980 cites W2064763329 @default.
• W3015377980 cites W2069186336 @default.
• W3015377980 cites W2080851537 @default.
• W3015377980 cites W2083857067 @default.
• W3015377980 cites W2088769034 @default.
• W3015377980 cites W2093902047 @default.
• W3015377980 cites W2095080219 @default.
• W3015377980 cites W2097186487 @default.
• W3015377980 cites W2112246161 @default.
• W3015377980 cites W2117794907 @default.
• W3015377980 cites W2125136135 @default.
• W3015377980 cites W2127187175 @default.
• W3015377980 cites W2129054103 @default.
• W3015377980 cites W2129906068 @default.
• W3015377980 cites W2131938193 @default.
• W3015377980 cites W2137171341 @default.
• W3015377980 cites W2138260451 @default.
• W3015377980 cites W2143821932 @default.
• W3015377980 cites W2162684274 @default.
• W3015377980 cites W2164333285 @default.
• W3015377980 cites W2166375192 @default.
• W3015377980 cites W2171281863 @default.
• W3015377980 cites W2171332611 @default.
• W3015377980 cites W2221454867 @default.
• W3015377980 cites W2339822075 @default.
• W3015377980 cites W2404664646 @default.
• W3015377980 cites W2431792021 @default.
• W3015377980 cites W2531038783 @default.
• W3015377980 cites W2555537874 @default.
• W3015377980 cites W2728290892 @default.
• W3015377980 cites W2751963815 @default.
• W3015377980 cites W2756946297 @default.
• W3015377980 cites W2765562046 @default.
• W3015377980 cites W2784345005 @default.
• W3015377980 cites W2790008006 @default.
• W3015377980 cites W2800553671 @default.
• W3015377980 cites W2807998183 @default.
• W3015377980 cites W2885749399 @default.
• W3015377980 cites W2888474428 @default.
• W3015377980 cites W2891505771 @default.
• W3015377980 cites W2892347062 @default.
• W3015377980 cites W2897061357 @default.
• W3015377980 cites W2921488499 @default.
• W3015377980 cites W2921523173 @default.
• W3015377980 cites W2946807361 @default.
• W3015377980 cites W2951902290 @default.
• W3015377980 cites W2952625560 @default.
• W3015377980 cites W2978989870 @default.
• W3015377980 cites W4237082306 @default.
• W3015377980 cites W4239861095 @default.
• W3015377980 doi "https://doi.org/10.1038/s41598-020-63169-3" @default.
• W3015377980 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7145822" @default.
• W3015377980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32273557" @default.

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