FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3015498906> ?p ?o ?g. }

• W3015498906 endingPage "91" @default.
• W3015498906 startingPage "84" @default.
• W3015498906 abstract "In order to show that reduced functional capacity in subclinical heart failure portends a higher risk of clinically overt (stage C) heart failure, we obtained the Duke activity status index (DASI) and 6-minute walk distance (6MWD) in 814 patients (age 70 [interquartile range 67 to 74] years, 51% female) with nonischemic subclinical heart failure. Reduced functional capacity was defined as: (1) DASI-derived metabolic equivalents <7, (2) 6MWD <2 standard deviations below the age-based normative mean (excluding those with mobility impairment) and (3) reduced 6MWD with reclassification where DASI was discordant. Based on reduced functional capacity and left ventricular dysfunction (LVD), subjects were classified into; (1) Stage A heart failure (436 with neither LVD nor reduced functional capacity), (2) Stage A with reduced functional capacity (n = 80), (3) Stage B heart failure (182 with LVD but preserved functional capacity) and (4) early stage C heart failure (52 with LVD and reduced functional capacity). Outcome was assessed by Kaplan-Meier survival estimates and Cox proportional hazard ratios. After a median follow-up of 13 months [interquartile range 11 to 19]), 76 (9%) developed heart failure - 6% of Stage A, 10% of Stage A-reduced functional capacity, 9% of Stage B and 37% of early Stage C (p < 0.001). After adjustment (for heart failure risk score, atrial fibrillation, pulmonary disease and therapy), the hazard ratio for development of overt heart failure in early Stage C was 5.92 (95% confidence intervals 2.92 to 11.54, p < 0.001) compared with Stage A and 3.08 (95% confidence intervals 1.47 to 6.47, p = 0.003) compared with Stage B. In order to show that reduced functional capacity in subclinical heart failure portends a higher risk of clinically overt (stage C) heart failure, we obtained the Duke activity status index (DASI) and 6-minute walk distance (6MWD) in 814 patients (age 70 [interquartile range 67 to 74] years, 51% female) with nonischemic subclinical heart failure. Reduced functional capacity was defined as: (1) DASI-derived metabolic equivalents <7, (2) 6MWD <2 standard deviations below the age-based normative mean (excluding those with mobility impairment) and (3) reduced 6MWD with reclassification where DASI was discordant. Based on reduced functional capacity and left ventricular dysfunction (LVD), subjects were classified into; (1) Stage A heart failure (436 with neither LVD nor reduced functional capacity), (2) Stage A with reduced functional capacity (n = 80), (3) Stage B heart failure (182 with LVD but preserved functional capacity) and (4) early stage C heart failure (52 with LVD and reduced functional capacity). Outcome was assessed by Kaplan-Meier survival estimates and Cox proportional hazard ratios. After a median follow-up of 13 months [interquartile range 11 to 19]), 76 (9%) developed heart failure - 6% of Stage A, 10% of Stage A-reduced functional capacity, 9% of Stage B and 37% of early Stage C (p < 0.001). After adjustment (for heart failure risk score, atrial fibrillation, pulmonary disease and therapy), the hazard ratio for development of overt heart failure in early Stage C was 5.92 (95% confidence intervals 2.92 to 11.54, p < 0.001) compared with Stage A and 3.08 (95% confidence intervals 1.47 to 6.47, p = 0.003) compared with Stage B." @default.
• W3015498906 created "2020-04-17" @default.
• W3015498906 creator A5011206008 @default.
• W3015498906 creator A5039644141 @default.
• W3015498906 creator A5063396957 @default.
• W3015498906 creator A5077985621 @default.
• W3015498906 creator A5082115800 @default.
• W3015498906 date "2020-07-01" @default.
• W3015498906 modified "2023-09-27" @default.
• W3015498906 title "Measurement of Functional Capacity to Discriminate Clinical from Subclinical Heart Failure in Patients ≥65 Years of Age" @default.
• W3015498906 cites W2004733118 @default.
• W3015498906 cites W2025953928 @default.
• W3015498906 cites W2033969839 @default.
• W3015498906 cites W2039760601 @default.
• W3015498906 cites W2039994436 @default.
• W3015498906 cites W2046805493 @default.
• W3015498906 cites W2053219593 @default.
• W3015498906 cites W2056914680 @default.
• W3015498906 cites W2062884888 @default.
• W3015498906 cites W2067885332 @default.
• W3015498906 cites W2108458974 @default.
• W3015498906 cites W2124624517 @default.
• W3015498906 cites W2126617656 @default.
• W3015498906 cites W2139605571 @default.
• W3015498906 cites W2143454209 @default.
• W3015498906 cites W2156441323 @default.
• W3015498906 cites W2195520254 @default.
• W3015498906 cites W2279897032 @default.
• W3015498906 cites W2313186535 @default.
• W3015498906 cites W2313960840 @default.
• W3015498906 cites W2323862874 @default.
• W3015498906 cites W2343158650 @default.
• W3015498906 cites W2554655675 @default.
• W3015498906 cites W2623867926 @default.
• W3015498906 cites W2790015075 @default.
• W3015498906 cites W37647394 @default.
• W3015498906 cites W4245666729 @default.
• W3015498906 cites W4296747967 @default.
• W3015498906 doi "https://doi.org/10.1016/j.amjcard.2020.03.051" @default.
• W3015498906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32418718" @default.
• W3015498906 hasPublicationYear "2020" @default.
• W3015498906 type Work @default.
• W3015498906 sameAs 3015498906 @default.
• W3015498906 citedByCount "3" @default.
• W3015498906 countsByYear W30154989062021 @default.
• W3015498906 countsByYear W30154989062023 @default.
• W3015498906 crossrefType "journal-article" @default.
• W3015498906 hasAuthorship W3015498906A5011206008 @default.
• W3015498906 hasAuthorship W3015498906A5039644141 @default.
• W3015498906 hasAuthorship W3015498906A5063396957 @default.
• W3015498906 hasAuthorship W3015498906A5077985621 @default.
• W3015498906 hasAuthorship W3015498906A5082115800 @default.
• W3015498906 hasConcept C113280763 @default.
• W3015498906 hasConcept C119060515 @default.
• W3015498906 hasConcept C126322002 @default.
• W3015498906 hasConcept C146357865 @default.
• W3015498906 hasConcept C151730666 @default.
• W3015498906 hasConcept C164705383 @default.
• W3015498906 hasConcept C207103383 @default.
• W3015498906 hasConcept C2778198053 @default.
• W3015498906 hasConcept C2779161974 @default.
• W3015498906 hasConcept C2780074459 @default.
• W3015498906 hasConcept C44249647 @default.
• W3015498906 hasConcept C50382708 @default.
• W3015498906 hasConcept C71924100 @default.
• W3015498906 hasConcept C86803240 @default.
• W3015498906 hasConceptScore W3015498906C113280763 @default.
• W3015498906 hasConceptScore W3015498906C119060515 @default.
• W3015498906 hasConceptScore W3015498906C126322002 @default.
• W3015498906 hasConceptScore W3015498906C146357865 @default.
• W3015498906 hasConceptScore W3015498906C151730666 @default.
• W3015498906 hasConceptScore W3015498906C164705383 @default.
• W3015498906 hasConceptScore W3015498906C207103383 @default.
• W3015498906 hasConceptScore W3015498906C2778198053 @default.
• W3015498906 hasConceptScore W3015498906C2779161974 @default.
• W3015498906 hasConceptScore W3015498906C2780074459 @default.
• W3015498906 hasConceptScore W3015498906C44249647 @default.
• W3015498906 hasConceptScore W3015498906C50382708 @default.
• W3015498906 hasConceptScore W3015498906C71924100 @default.
• W3015498906 hasConceptScore W3015498906C86803240 @default.
• W3015498906 hasFunder F4320334705 @default.
• W3015498906 hasLocation W30154989061 @default.
• W3015498906 hasLocation W30154989062 @default.
• W3015498906 hasOpenAccess W3015498906 @default.
• W3015498906 hasPrimaryLocation W30154989061 @default.
• W3015498906 hasRelatedWork W2067977631 @default.
• W3015498906 hasRelatedWork W2174666533 @default.
• W3015498906 hasRelatedWork W2300086221 @default.
• W3015498906 hasRelatedWork W2738948630 @default.
• W3015498906 hasRelatedWork W2784029422 @default.
• W3015498906 hasRelatedWork W2947523721 @default.
• W3015498906 hasRelatedWork W3029306217 @default.
• W3015498906 hasRelatedWork W3037194828 @default.
• W3015498906 hasRelatedWork W3091935110 @default.
• W3015498906 hasRelatedWork W4212816370 @default.
• W3015498906 hasVolume "127" @default.
• W3015498906 isParatext "false" @default.
• W3015498906 isRetracted "false" @default.

• next