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• W3015569811 abstract "Abstract Carnosine plays an important role in regulating muscle buffering capacity and glycolysis. In order to investigate the effects of dietary β -alanine, L-histidine, and L-carnosine supplementation on the pH value, glycolytic potential, the activities of AMP-activated protein kinase (AMPK) and pyruvate kinase (PK) activities in the porcine longissimus dorsi muscle, a total of 60 barrows with an average body weight (BW) of 50.5 ± 1.7 kg were assigned into five groups which received diets containing basal diet (control, CON), 0.04% β -alanine ( β -ALA), 0.06% L-histidine (L-HIS), 0.04% β -alanine+0.06% L-histidine ( β -ALA+L-HIS), or 0.1% L-carnosine (L-CAR). The results showed that dietary supplementation of the combination of β -ALA and L-HIS or L-CAR significantly increased ( P < 0.05) the average daily gain (ADG) of pigs with 50-75 kg BW, compared with other three groups. Compared with L-CAR group, L-HIS supplementation significantly decreased ( P < 0.05) the average daily feed intake (ADFI) of pigs. There were no significant difference ( P > 0.05) in back fat thickness and loin eye area among treatments. At 0, 1 and 24 h postmortem (PM) the pH values in the longissimus dorsi muscle (LM) of pigs receiving L-CAR were higher ( P < 0.05) than that of pigs receiving CON diet. The redness (a*) values of LM of pigs in the β -ALA+L-HIS or L-CAR group were higher ( P < 0.05) than those in other three groups. The glycolytic potential of LM was not significantly different ( P > 0.05) among treatments. At 1, 24 h PM the AMPK activities in LM of pigs receiving β -ALA, β -ALA+L-HIS and L-CAR were much lower ( P < 0.05) than those of pigs receiving CON diet or L-HIS. 0.1% L-carnosine or 0.04% β -alanine supplemented to pigs’ diet was effective in regulating AMPK and PK activities in the porcine longissimus dorsi muscle and preventing the development of pale, soft and exudative (PSE) pork." @default.
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• W3015569811 date "2020-04-09" @default.
• W3015569811 modified "2023-09-27" @default.
• W3015569811 title "β-alanine or L-carnosine prevents the development of pale, soft and exudative pork by inhibiting the glycolysis of porcine longissimus dorsi muscle" @default.
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• W3015569811 doi "https://doi.org/10.1101/2020.04.09.033225" @default.
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