FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3015593362> ?p ?o ?g. }

• W3015593362 endingPage "111310" @default.
• W3015593362 startingPage "111310" @default.
• W3015593362 abstract "Seven US FDA-batch certified synthetic food colors are approved for use as food additives in the United States. Perceived neurodevelopmental concerns for these colors persist. This study assessed the plausibility of such an association through the evaluation of mechanistic evidence collected from in vitro assays or other alternative models. Mechanisms and molecular targets underlying neurodevelopmental processes associated with attention deficit and hyperactivity disorder (ADHD) and other neurodevelopmental-related symptoms (e.g., cognitive function, learning and memory disorder, etc.) were identified. Publicly available data from the ToxCast/Tox21 high-throughput screening (HTS) program and peer-reviewed literature that measure activity of the colors for such molecular targets were analyzed and reviewed. Erythrosine (Red No. 3) was active in several assays mapped to neurodevelopmental processes — specifically, HTS assays that measure signals in neurotransmitter pathways. The remaining six colors do not appear to alter signaling pathways related to neurodevelopmental processes on the molecular or cellular level. This assessment provides an approach for systematically identifying and mapping mechanistic data to putative neurodevelopmental processes as a means to prioritize substances for possible further investigation. The assessment also provides insights into the lack of activity of synthetic food colors for key events in neurodevelopmental signaling pathways." @default.
• W3015593362 created "2020-04-17" @default.
• W3015593362 creator A5031046579 @default.
• W3015593362 creator A5045366873 @default.
• W3015593362 creator A5078289176 @default.
• W3015593362 date "2020-06-01" @default.
• W3015593362 modified "2023-10-01" @default.
• W3015593362 title "Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes" @default.
• W3015593362 cites W1507257996 @default.
• W3015593362 cites W1918261394 @default.
• W3015593362 cites W1934774777 @default.
• W3015593362 cites W1967706805 @default.
• W3015593362 cites W1970124769 @default.
• W3015593362 cites W1973016692 @default.
• W3015593362 cites W1982681955 @default.
• W3015593362 cites W1983030849 @default.
• W3015593362 cites W1990268025 @default.
• W3015593362 cites W1992104457 @default.
• W3015593362 cites W2000474355 @default.
• W3015593362 cites W2002577153 @default.
• W3015593362 cites W2004427810 @default.
• W3015593362 cites W2007069550 @default.
• W3015593362 cites W2010561013 @default.
• W3015593362 cites W2012425850 @default.
• W3015593362 cites W2026068701 @default.
• W3015593362 cites W2030073764 @default.
• W3015593362 cites W2035070784 @default.
• W3015593362 cites W2037337146 @default.
• W3015593362 cites W2041326043 @default.
• W3015593362 cites W2043241709 @default.
• W3015593362 cites W2051175597 @default.
• W3015593362 cites W2057533468 @default.
• W3015593362 cites W2062199416 @default.
• W3015593362 cites W2064990262 @default.
• W3015593362 cites W2066254606 @default.
• W3015593362 cites W2071505143 @default.
• W3015593362 cites W2072209654 @default.
• W3015593362 cites W2075372558 @default.
• W3015593362 cites W2084459193 @default.
• W3015593362 cites W2088183908 @default.
• W3015593362 cites W2090715675 @default.
• W3015593362 cites W2090813178 @default.
• W3015593362 cites W2097471815 @default.
• W3015593362 cites W2101886959 @default.
• W3015593362 cites W2116325315 @default.
• W3015593362 cites W2122025333 @default.
• W3015593362 cites W2132917502 @default.
• W3015593362 cites W2141557060 @default.
• W3015593362 cites W2142705057 @default.
• W3015593362 cites W2145165825 @default.
• W3015593362 cites W2148130301 @default.
• W3015593362 cites W2149472336 @default.
• W3015593362 cites W2152739465 @default.
• W3015593362 cites W2167139179 @default.
• W3015593362 cites W2340139863 @default.
• W3015593362 cites W2397394044 @default.
• W3015593362 cites W2546044736 @default.
• W3015593362 cites W2602358262 @default.
• W3015593362 cites W2602774126 @default.
• W3015593362 cites W2604883481 @default.
• W3015593362 cites W2605935790 @default.
• W3015593362 cites W2615223867 @default.
• W3015593362 cites W2778593014 @default.
• W3015593362 cites W2788960134 @default.
• W3015593362 cites W2794829772 @default.
• W3015593362 cites W2802815532 @default.
• W3015593362 cites W2808011097 @default.
• W3015593362 cites W2884182920 @default.
• W3015593362 cites W2902929934 @default.
• W3015593362 cites W2914958489 @default.
• W3015593362 cites W2916047525 @default.
• W3015593362 cites W2969972105 @default.
• W3015593362 cites W3006146816 @default.
• W3015593362 cites W3013301991 @default.
• W3015593362 cites W4238784014 @default.
• W3015593362 cites W4249823481 @default.
• W3015593362 cites W898060796 @default.
• W3015593362 doi "https://doi.org/10.1016/j.fct.2020.111310" @default.
• W3015593362 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32275932" @default.
• W3015593362 hasPublicationYear "2020" @default.
• W3015593362 type Work @default.
• W3015593362 sameAs 3015593362 @default.
• W3015593362 citedByCount "9" @default.
• W3015593362 countsByYear W30155933622021 @default.
• W3015593362 countsByYear W30155933622022 @default.
• W3015593362 countsByYear W30155933622023 @default.
• W3015593362 crossrefType "journal-article" @default.
• W3015593362 hasAuthorship W3015593362A5031046579 @default.
• W3015593362 hasAuthorship W3015593362A5045366873 @default.
• W3015593362 hasAuthorship W3015593362A5078289176 @default.
• W3015593362 hasBestOaLocation W30155933621 @default.
• W3015593362 hasConcept C118552586 @default.
• W3015593362 hasConcept C15744967 @default.
• W3015593362 hasConcept C169760540 @default.
• W3015593362 hasConcept C205778803 @default.
• W3015593362 hasConcept C2779388368 @default.
• W3015593362 hasConcept C2780783007 @default.
• W3015593362 hasConceptScore W3015593362C118552586 @default.

• next