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- W3015684322 abstract "Imagine your worst fear realized as an oncologist confirms that your child has cancer. During the initial clinic visit, you will be informed of your child’s diagnosis and his or her prognosis1 contingent on the best available treatment protocol, usually based on years of comprehensive clinical research. In the uncommon case that no best-practice protocol is available for your child, treatment options will be presented for you to help choose a course of action. Ideally, that discussion will include the pros and cons of each choice, including prognostic estimates, acute toxicities, and potential long-term effects on your child’s health and psychosocial well-being as they may evolve over the life course. From knowledge gained through clinical research and observational follow-up studies of cancer cohorts,2 the unambiguous association between therapeutic exposures and specific acute and long-term effects in childhood cancer has led to a focus in treatment protocols on maintaining high survival probability while minimizing serious late effects and optimizing quality of life. For example, efforts to reduce late effects have included omission or reduction of … Address correspondence to James G. Gurney, PhD, School of Public Health, 236 Robison Hall, University of Memphis, Memphis, TN 38152. E-mail: jggurney{at}memphis.edu" @default.
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- W3015684322 date "2020-05-01" @default.
- W3015684322 modified "2023-09-23" @default.
- W3015684322 title "Early and Often: The Need for Comprehensive Discussion of Treatment-Induced Cancer Late Effects" @default.
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- W3015684322 doi "https://doi.org/10.1542/peds.2020-0498" @default.
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