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- W3015732832 abstract "Ceratonia siliqua L. is a Mediterranean medicinal plant traditionally cultivated for its ethnopharmacological benefits, such as antidiarrheal, antidiabetic, enhance acetylcholine, antioxidant, antiatherosclerotic, and for its possible anti-neurodegenerative potential. The aim of the present study was to evaluate the chemical composition, as well as the cognitive-enhancing, anxiolytic, and antioxidant activities of the aqueous extract from C. siliqua (CsAE) leaves against 6-hydroxydopamine (6-OHDA) zebrafish Parkinson’s disease (PD) model. CsAE (0.1, 0.3, and 1 mg/L) was administered by immersion to zebrafish (Danio rerio) for eight consecutive days and one hour before each behavioral test of each day, while 6-OHDA (250 µM) treatment was supplied one day before the novel tank diving test (NTT). Qualitative and quantitative analyses were performed by the ultra-high-performance liquid chromatography (UHPLC) analysis. The memory performance was evaluated through the NTT and Y-maze tests. Additionally, the in vitro and in vivo antioxidant status and acetylcholinesterase (AChE) activity was also assessed. Our finds demonstrated that CsAE presented positive antioxidant and anti-AChE activities, which contributed to the improvement of cognitive function in the 6-OHDA zebrafish PD model." @default.
- W3015732832 created "2020-04-17" @default.
- W3015732832 creator A5005348221 @default.
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- W3015732832 creator A5085662469 @default.
- W3015732832 date "2020-04-08" @default.
- W3015732832 modified "2023-10-18" @default.
- W3015732832 title "The Aqueous Extract from Ceratonia siliqua Leaves Protects against 6-Hydroxydopamine in Zebrafish: Understanding the Underlying Mechanism" @default.
- W3015732832 cites W1104977322 @default.
- W3015732832 cites W1255597286 @default.
- W3015732832 cites W1514771097 @default.
- W3015732832 cites W1605811996 @default.
- W3015732832 cites W1960711550 @default.
- W3015732832 cites W1971338155 @default.
- W3015732832 cites W1971543005 @default.
- W3015732832 cites W1971757965 @default.
- W3015732832 cites W1972009654 @default.
- W3015732832 cites W1975205078 @default.
- W3015732832 cites W1976950210 @default.
- W3015732832 cites W1977853986 @default.
- W3015732832 cites W1980043169 @default.
- W3015732832 cites W1980143715 @default.
- W3015732832 cites W1986464172 @default.
- W3015732832 cites W1986724174 @default.
- W3015732832 cites W1989498664 @default.
- W3015732832 cites W1990275174 @default.
- W3015732832 cites W1991715802 @default.
- W3015732832 cites W1992483445 @default.
- W3015732832 cites W1997258141 @default.
- W3015732832 cites W1997520177 @default.
- W3015732832 cites W2000257716 @default.
- W3015732832 cites W2001726712 @default.
- W3015732832 cites W2005228261 @default.
- W3015732832 cites W2005682045 @default.
- W3015732832 cites W2008778696 @default.
- W3015732832 cites W2010635045 @default.
- W3015732832 cites W2014611703 @default.
- W3015732832 cites W2015393151 @default.
- W3015732832 cites W2017386898 @default.
- W3015732832 cites W2022155997 @default.
- W3015732832 cites W2022544336 @default.
- W3015732832 cites W2023551843 @default.
- W3015732832 cites W2024211635 @default.
- W3015732832 cites W2024992930 @default.
- W3015732832 cites W2030349284 @default.
- W3015732832 cites W2030689931 @default.
- W3015732832 cites W2030882694 @default.
- W3015732832 cites W2031861429 @default.
- W3015732832 cites W2031928368 @default.
- W3015732832 cites W2034131386 @default.
- W3015732832 cites W2036210555 @default.
- W3015732832 cites W2037615866 @default.
- W3015732832 cites W2038702047 @default.
- W3015732832 cites W2040711202 @default.
- W3015732832 cites W2043847095 @default.
- W3015732832 cites W2044230090 @default.
- W3015732832 cites W2044273528 @default.
- W3015732832 cites W2046212966 @default.
- W3015732832 cites W2052208520 @default.
- W3015732832 cites W2052714833 @default.
- W3015732832 cites W2055835221 @default.
- W3015732832 cites W2058074769 @default.
- W3015732832 cites W2060104534 @default.
- W3015732832 cites W2062666762 @default.
- W3015732832 cites W2062945796 @default.
- W3015732832 cites W2064248739 @default.
- W3015732832 cites W2068813102 @default.
- W3015732832 cites W2074512118 @default.
- W3015732832 cites W2074804915 @default.
- W3015732832 cites W2075890649 @default.
- W3015732832 cites W2078592874 @default.
- W3015732832 cites W2078860848 @default.
- W3015732832 cites W2080744985 @default.
- W3015732832 cites W2082436494 @default.
- W3015732832 cites W2087598124 @default.
- W3015732832 cites W2087993101 @default.
- W3015732832 cites W2089071120 @default.
- W3015732832 cites W2090897569 @default.
- W3015732832 cites W2101304082 @default.
- W3015732832 cites W2112175087 @default.
- W3015732832 cites W2121019339 @default.
- W3015732832 cites W2123672967 @default.
- W3015732832 cites W2126386203 @default.
- W3015732832 cites W2128443648 @default.
- W3015732832 cites W2131587794 @default.
- W3015732832 cites W2160439669 @default.
- W3015732832 cites W2161253031 @default.
- W3015732832 cites W2161717772 @default.
- W3015732832 cites W2162775768 @default.
- W3015732832 cites W2171742547 @default.
- W3015732832 cites W2188278071 @default.
- W3015732832 cites W2286341428 @default.
- W3015732832 cites W2290994411 @default.