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- W3015905863 abstract "Unnatural amino acids are key building blocks in therapeutically relevant peptides. Thus, the development of novel methods to increase the structural diversity of the unnatural amino acid pool is needed. Herein, a photoredox-mediated decarboxylative radical conjugate addition to dehydroalanine derivatives is disclosed. Mild, robust, and general conditions were identified and applied to the diastereoselective synthesis of unnatural amino acids and the late-stage derivatization of a tripeptide." @default.
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- W3015905863 date "2020-04-09" @default.
- W3015905863 modified "2023-10-18" @default.
- W3015905863 title "Derivatization of Amino Acids and Peptides via Photoredox-Mediated Conjugate Addition" @default.
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- W3015905863 doi "https://doi.org/10.1021/acs.joc.0c00635" @default.
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