Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016047136> ?p ?o ?g. }
- W3016047136 endingPage "1749" @default.
- W3016047136 startingPage "1749" @default.
- W3016047136 abstract "The leaves of Pyrola rotundifolia L. were extracted in the mixed solvent of methanol/acetone/water (2:2:1, v/v/v) and investigated for their phytochemical analysis and biological activity. Total phenolic and flavonoid contents were determined spectrophotometrically. A high content of phenols (208.35 mg GAE/g of dry extract), flavonoids (38.90 mg QE/g of dry extract) and gallotannins (722.91 GAE/g of dry extract) was obtained. Ultra-high performance liquid chromatography diode array detector tandem mass spectrometry (UHPLC–DAD–MS) allowed for the detection of 23 major peaks at 254 nm. The extract was analyzed for its antioxidant capacity using 2,2-diphenyl-1-picryl-hydrazyl (DPPH•) and 2,2′-azinobis[3-ethylbenzthiazoline]-6-sulfonic acid (ABTS•+) radical scavenging, metal chelating power and β-carotene-linoleic acid bleaching assays. The examined extract showed moderate radical scavenging and chelating activity, and good inhibiting ability of linoleic acid oxidation (EC50 = 0.05 mg/mL) in comparison to standards. The cytotoxic effect in increasing concentration on five types of leukemic cell lines was also investigated using trypan blue vital staining. It was found that the analyzed extract induced the apoptosis of all the tested cell lines. Our findings suggest that the leaves of P. rotundifolia are a source of valuable compounds providing protection against oxidative damage, hence their use in traditional medicine is justified." @default.
- W3016047136 created "2020-04-17" @default.
- W3016047136 creator A5003597153 @default.
- W3016047136 creator A5010775034 @default.
- W3016047136 creator A5038785706 @default.
- W3016047136 creator A5049516766 @default.
- W3016047136 creator A5059033443 @default.
- W3016047136 date "2020-04-10" @default.
- W3016047136 modified "2023-09-23" @default.
- W3016047136 title "Phenolic Composition of the Leaves of Pyrola rotundifolia L. and Their Antioxidant and Cytotoxic Activity" @default.
- W3016047136 cites W1526856981 @default.
- W3016047136 cites W1600410642 @default.
- W3016047136 cites W1950487283 @default.
- W3016047136 cites W1965413634 @default.
- W3016047136 cites W1965880422 @default.
- W3016047136 cites W1975929099 @default.
- W3016047136 cites W1977870427 @default.
- W3016047136 cites W1982862374 @default.
- W3016047136 cites W1995870433 @default.
- W3016047136 cites W1998684547 @default.
- W3016047136 cites W2004158208 @default.
- W3016047136 cites W2007300070 @default.
- W3016047136 cites W2012590859 @default.
- W3016047136 cites W2015199985 @default.
- W3016047136 cites W2015560109 @default.
- W3016047136 cites W2018423366 @default.
- W3016047136 cites W2026971953 @default.
- W3016047136 cites W2028692031 @default.
- W3016047136 cites W2029752387 @default.
- W3016047136 cites W2048553024 @default.
- W3016047136 cites W2051877749 @default.
- W3016047136 cites W2059350161 @default.
- W3016047136 cites W2062187703 @default.
- W3016047136 cites W2065468492 @default.
- W3016047136 cites W2068371326 @default.
- W3016047136 cites W2069066211 @default.
- W3016047136 cites W2078920771 @default.
- W3016047136 cites W2084585214 @default.
- W3016047136 cites W2086683506 @default.
- W3016047136 cites W2091228079 @default.
- W3016047136 cites W2092685208 @default.
- W3016047136 cites W2105731956 @default.
- W3016047136 cites W2128473487 @default.
- W3016047136 cites W2132738767 @default.
- W3016047136 cites W2149210021 @default.
- W3016047136 cites W2150033386 @default.
- W3016047136 cites W2156555795 @default.
- W3016047136 cites W2160189829 @default.
- W3016047136 cites W2167607663 @default.
- W3016047136 cites W2168556140 @default.
- W3016047136 cites W2314361085 @default.
- W3016047136 cites W2332888089 @default.
- W3016047136 cites W2332982320 @default.
- W3016047136 cites W2621011961 @default.
- W3016047136 cites W2771716313 @default.
- W3016047136 cites W2887671808 @default.
- W3016047136 cites W2927016897 @default.
- W3016047136 cites W2970507027 @default.
- W3016047136 cites W927940047 @default.
- W3016047136 doi "https://doi.org/10.3390/molecules25071749" @default.
- W3016047136 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7180938" @default.
- W3016047136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32290223" @default.
- W3016047136 hasPublicationYear "2020" @default.
- W3016047136 type Work @default.
- W3016047136 sameAs 3016047136 @default.
- W3016047136 citedByCount "14" @default.
- W3016047136 countsByYear W30160471362020 @default.
- W3016047136 countsByYear W30160471362021 @default.
- W3016047136 countsByYear W30160471362022 @default.
- W3016047136 countsByYear W30160471362023 @default.
- W3016047136 crossrefType "journal-article" @default.
- W3016047136 hasAuthorship W3016047136A5003597153 @default.
- W3016047136 hasAuthorship W3016047136A5010775034 @default.
- W3016047136 hasAuthorship W3016047136A5038785706 @default.
- W3016047136 hasAuthorship W3016047136A5049516766 @default.
- W3016047136 hasAuthorship W3016047136A5059033443 @default.
- W3016047136 hasBestOaLocation W30160471361 @default.
- W3016047136 hasConcept C178790620 @default.
- W3016047136 hasConcept C185592680 @default.
- W3016047136 hasConcept C195475562 @default.
- W3016047136 hasConcept C2777728882 @default.
- W3016047136 hasConcept C2778004101 @default.
- W3016047136 hasConcept C2778362808 @default.
- W3016047136 hasConcept C2778945092 @default.
- W3016047136 hasConcept C2779054382 @default.
- W3016047136 hasConcept C2780809830 @default.
- W3016047136 hasConcept C2781031786 @default.
- W3016047136 hasConcept C2781401929 @default.
- W3016047136 hasConcept C31903555 @default.
- W3016047136 hasConcept C43617362 @default.
- W3016047136 hasConcept C543025807 @default.
- W3016047136 hasConcept C55493867 @default.
- W3016047136 hasConceptScore W3016047136C178790620 @default.
- W3016047136 hasConceptScore W3016047136C185592680 @default.
- W3016047136 hasConceptScore W3016047136C195475562 @default.
- W3016047136 hasConceptScore W3016047136C2777728882 @default.
- W3016047136 hasConceptScore W3016047136C2778004101 @default.
- W3016047136 hasConceptScore W3016047136C2778362808 @default.