Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016087331> ?p ?o ?g. }
- W3016087331 abstract "Transitional metal ions widely exist in biological environments and are crucial to many life-sustaining physiological processes. Recently, transition metal ion such as Cu$^{2+}$, Zn$^{2+}$, Ni$^{2+}$, have been shown can increase the solubilities of aromatic biomolecules. Comparing with Cu$^{2+}$, Zn$^{2+}$ shows less enhancement to the solubilities of biomolecules such as tryptophan (Trp). On the other hand, Zn$^{2+}$ has a higher concentration in human blood plasma and appears in protein the most among transition metal ions, clarifying whether Zn$^{2+}$ can enhance the solubilities of other aromatic amino acids is significantly important. Herein, we observed that the solubility of aromatic amino acid histidine (His) is greatly enhanced in ZnCl$_2$ solution. Based on first principle calculations, this enhancement of solubility is attributed to cation-$pi$ interaction between His and Zn$^{2+}$. Our results here are of great importance for the bioavailability of aromatic drugs and provide new insights for the understanding of physiological functions of Zn$^{2+}$." @default.
- W3016087331 created "2020-04-17" @default.
- W3016087331 creator A5006482718 @default.
- W3016087331 creator A5009628912 @default.
- W3016087331 creator A5014003649 @default.
- W3016087331 creator A5034465744 @default.
- W3016087331 creator A5037998311 @default.
- W3016087331 creator A5054462371 @default.
- W3016087331 creator A5066325577 @default.
- W3016087331 date "2020-04-07" @default.
- W3016087331 modified "2023-09-25" @default.
- W3016087331 title "Enhanced water affinity of histidine by transition metal ions" @default.
- W3016087331 cites W1727865142 @default.
- W3016087331 cites W1969462066 @default.
- W3016087331 cites W1992661805 @default.
- W3016087331 cites W2007628177 @default.
- W3016087331 cites W2010076108 @default.
- W3016087331 cites W2015517515 @default.
- W3016087331 cites W2029040745 @default.
- W3016087331 cites W2030393474 @default.
- W3016087331 cites W2058647911 @default.
- W3016087331 cites W2060229787 @default.
- W3016087331 cites W2077767650 @default.
- W3016087331 cites W2081172203 @default.
- W3016087331 cites W2113353236 @default.
- W3016087331 cites W2126029305 @default.
- W3016087331 cites W2131781277 @default.
- W3016087331 cites W2139916893 @default.
- W3016087331 cites W2160309942 @default.
- W3016087331 cites W2169303530 @default.
- W3016087331 cites W2335434301 @default.
- W3016087331 cites W2558911994 @default.
- W3016087331 cites W2964344211 @default.
- W3016087331 doi "https://doi.org/10.48550/arxiv.2004.03798" @default.
- W3016087331 hasPublicationYear "2020" @default.
- W3016087331 type Work @default.
- W3016087331 sameAs 3016087331 @default.
- W3016087331 citedByCount "0" @default.
- W3016087331 crossrefType "posted-content" @default.
- W3016087331 hasAuthorship W3016087331A5006482718 @default.
- W3016087331 hasAuthorship W3016087331A5009628912 @default.
- W3016087331 hasAuthorship W3016087331A5014003649 @default.
- W3016087331 hasAuthorship W3016087331A5034465744 @default.
- W3016087331 hasAuthorship W3016087331A5037998311 @default.
- W3016087331 hasAuthorship W3016087331A5054462371 @default.
- W3016087331 hasAuthorship W3016087331A5066325577 @default.
- W3016087331 hasBestOaLocation W30160873311 @default.
- W3016087331 hasConcept C106773901 @default.
- W3016087331 hasConcept C145148216 @default.
- W3016087331 hasConcept C155574463 @default.
- W3016087331 hasConcept C161790260 @default.
- W3016087331 hasConcept C178790620 @default.
- W3016087331 hasConcept C179104552 @default.
- W3016087331 hasConcept C181389837 @default.
- W3016087331 hasConcept C185592680 @default.
- W3016087331 hasConcept C199164860 @default.
- W3016087331 hasConcept C2776706248 @default.
- W3016087331 hasConcept C2777992278 @default.
- W3016087331 hasConcept C2778460671 @default.
- W3016087331 hasConcept C49853544 @default.
- W3016087331 hasConcept C515207424 @default.
- W3016087331 hasConcept C535196362 @default.
- W3016087331 hasConcept C544153396 @default.
- W3016087331 hasConcept C55493867 @default.
- W3016087331 hasConcept C60644358 @default.
- W3016087331 hasConcept C86803240 @default.
- W3016087331 hasConceptScore W3016087331C106773901 @default.
- W3016087331 hasConceptScore W3016087331C145148216 @default.
- W3016087331 hasConceptScore W3016087331C155574463 @default.
- W3016087331 hasConceptScore W3016087331C161790260 @default.
- W3016087331 hasConceptScore W3016087331C178790620 @default.
- W3016087331 hasConceptScore W3016087331C179104552 @default.
- W3016087331 hasConceptScore W3016087331C181389837 @default.
- W3016087331 hasConceptScore W3016087331C185592680 @default.
- W3016087331 hasConceptScore W3016087331C199164860 @default.
- W3016087331 hasConceptScore W3016087331C2776706248 @default.
- W3016087331 hasConceptScore W3016087331C2777992278 @default.
- W3016087331 hasConceptScore W3016087331C2778460671 @default.
- W3016087331 hasConceptScore W3016087331C49853544 @default.
- W3016087331 hasConceptScore W3016087331C515207424 @default.
- W3016087331 hasConceptScore W3016087331C535196362 @default.
- W3016087331 hasConceptScore W3016087331C544153396 @default.
- W3016087331 hasConceptScore W3016087331C55493867 @default.
- W3016087331 hasConceptScore W3016087331C60644358 @default.
- W3016087331 hasConceptScore W3016087331C86803240 @default.
- W3016087331 hasLocation W30160873311 @default.
- W3016087331 hasOpenAccess W3016087331 @default.
- W3016087331 hasPrimaryLocation W30160873311 @default.
- W3016087331 hasRelatedWork W166413464 @default.
- W3016087331 hasRelatedWork W1852771592 @default.
- W3016087331 hasRelatedWork W2020778998 @default.
- W3016087331 hasRelatedWork W2035203893 @default.
- W3016087331 hasRelatedWork W2059815464 @default.
- W3016087331 hasRelatedWork W2060174226 @default.
- W3016087331 hasRelatedWork W2525551150 @default.
- W3016087331 hasRelatedWork W3016087331 @default.
- W3016087331 hasRelatedWork W3208936745 @default.
- W3016087331 hasRelatedWork W1970260943 @default.
- W3016087331 isParatext "false" @default.
- W3016087331 isRetracted "false" @default.