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• W3016141546 endingPage "1259" @default.
• W3016141546 startingPage "1248" @default.
• W3016141546 abstract "BACKGROUND Medium-chain triglyceride (MCT) enriched diet has a positive effect on seizure control and behavior in some dogs with idiopathic epilepsy (IE). OBJECTIVE To evaluate the short-term efficacy of MCTs administered as an add-on dietary supplement (DS) to a variable base diet to assess seizure control and antiseizure drug's (ASD) adverse effect profiles. ANIMALS Twenty-eight dogs with International Veterinary Epilepsy Task Force Tier II (IVETF) level diagnosis of treated IE with 3 or more seizures in the last 3 months were used. METHODS A 6-month multicenter, prospective, randomized, double-blinded, placebo-controlled crossover trial was completed, comparing an MCT-DS with a control-DS. A 9% metabolic energy-based amount of MCT or control oil was supplemented to the dogs' diet for 3 months, followed by a control oil or MCT for another 3 months, respectively. Dogs enrolled in this study satisfied most requirements of IE diagnosis stated by the IVETF II level. If they received an oil DS or drugs that could influence the metabolism of the investigated DS or chronic ASD, the chronic ASD medication was adjusted, or other causes of epilepsy were found, the dogs were excluded from the study. RESULTS Seizure frequency (median 2.51/month [0-6.67] versus 2.67/month [0-10.45]; P = .02) and seizure-day frequency were significantly (1.68/month [0-5.60] versus 1.99/month [0-7.42], P = .01) lower when dogs were fed MCT-DS in comparison with the control-DS. Two dogs were free of seizures, 3 had ≥50% and 12 had <50% reductions in seizure frequency, and 11 dogs showed no change or an increase in seizure frequency. CONCLUSIONS AND CLINICAL IMPORTANCE These data show antiseizure properties of an MCT-DS compared to a control oil and support former evidence for the efficacy of MCTs as a nutritive, management option for a subpopulation of drug-resistant dogs with epilepsy." @default.
• W3016141546 created "2020-04-17" @default.
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• W3016141546 date "2020-04-15" @default.
• W3016141546 modified "2023-10-12" @default.
• W3016141546 title "A multicenter randomized controlled trial of medium‐chain triglyceride dietary supplementation on epilepsy in dogs" @default.
• W3016141546 cites W105915516 @default.
• W3016141546 cites W1065309053 @default.
• W3016141546 cites W1512119355 @default.
• W3016141546 cites W1860822802 @default.
• W3016141546 cites W1911601438 @default.
• W3016141546 cites W1912129526 @default.
• W3016141546 cites W1941436389 @default.
• W3016141546 cites W1941551863 @default.
• W3016141546 cites W1963602712 @default.
• W3016141546 cites W1970885449 @default.
• W3016141546 cites W1977870236 @default.
• W3016141546 cites W1991490766 @default.
• W3016141546 cites W1991637580 @default.
• W3016141546 cites W1992641853 @default.
• W3016141546 cites W1993003469 @default.
• W3016141546 cites W2003037708 @default.
• W3016141546 cites W2006780292 @default.
• W3016141546 cites W2015074132 @default.
• W3016141546 cites W2018643148 @default.
• W3016141546 cites W2020068083 @default.
• W3016141546 cites W2020245702 @default.
• W3016141546 cites W2023348776 @default.
• W3016141546 cites W2023983971 @default.
• W3016141546 cites W2024110519 @default.
• W3016141546 cites W2026311526 @default.
• W3016141546 cites W2027329984 @default.
• W3016141546 cites W2032836163 @default.
• W3016141546 cites W2034490253 @default.
• W3016141546 cites W2045970301 @default.
• W3016141546 cites W2058767113 @default.
• W3016141546 cites W2062494166 @default.
• W3016141546 cites W2072962455 @default.
• W3016141546 cites W2073316691 @default.
• W3016141546 cites W2073871994 @default.
• W3016141546 cites W2078461915 @default.
• W3016141546 cites W2088648065 @default.
• W3016141546 cites W2089387667 @default.
• W3016141546 cites W2090276138 @default.
• W3016141546 cites W2101935092 @default.
• W3016141546 cites W2106324565 @default.
• W3016141546 cites W2106349700 @default.
• W3016141546 cites W2128636783 @default.
• W3016141546 cites W2129286287 @default.
• W3016141546 cites W2130375794 @default.
• W3016141546 cites W2132777822 @default.
• W3016141546 cites W2133152442 @default.
• W3016141546 cites W2146877035 @default.
• W3016141546 cites W2154193521 @default.
• W3016141546 cites W2160672274 @default.
• W3016141546 cites W2161771594 @default.
• W3016141546 cites W2169308848 @default.
• W3016141546 cites W2181121996 @default.
• W3016141546 cites W2222200714 @default.
• W3016141546 cites W2405439477 @default.
• W3016141546 cites W2460575698 @default.
• W3016141546 cites W2463213378 @default.
• W3016141546 cites W2468799633 @default.
• W3016141546 cites W2513078709 @default.
• W3016141546 cites W2524012533 @default.
• W3016141546 cites W2540809468 @default.
• W3016141546 cites W2552776938 @default.
• W3016141546 cites W2583795843 @default.
• W3016141546 cites W2592509339 @default.
• W3016141546 cites W2604406606 @default.
• W3016141546 cites W2605266778 @default.
• W3016141546 cites W2621572158 @default.
• W3016141546 cites W2732050928 @default.
• W3016141546 cites W2735230308 @default.
• W3016141546 cites W2769332924 @default.
• W3016141546 cites W2774052104 @default.
• W3016141546 cites W2779315858 @default.
• W3016141546 cites W2790441480 @default.
• W3016141546 cites W2791880529 @default.
• W3016141546 cites W2792478701 @default.
• W3016141546 cites W2796523839 @default.
• W3016141546 cites W2802495544 @default.
• W3016141546 cites W2810919418 @default.
• W3016141546 cites W2883279924 @default.
• W3016141546 cites W2883837346 @default.
• W3016141546 cites W2891971692 @default.
• W3016141546 cites W2895790198 @default.
• W3016141546 cites W2947300805 @default.

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