FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016185930> ?p ?o ?g. }

• W3016185930 endingPage "e0230422" @default.
• W3016185930 startingPage "e0230422" @default.
• W3016185930 abstract "The inability of beef cattle to maintain full term pregnancies has become an economic concern for the beef industry. Herd management and nutritional improvements have alleviated environmental impacts on embryonic and fetal loss, yet additional gains can be made through genomic selection. The objectives of this study were to identify loci and gene-sets in crossbred beef heifers associated with the number of services required to become pregnant (TBRD) and heifer conception rate at first service (HCR1). Heifers (n = 709) from a commercial beef operation underwent one round of artificial insemination, before exposure to bulls for natural service for 50 days. Pregnancy and time of conception was determined by ultrasound 35 days after the breeding season. Heifers were genotyped using the GeneSeek (Lincoln, NE) Bovine GGP50K BeadChip prior to genome-wide association analyses (GWAA) conducted using an EIGENSTRAT-like model to identify loci associated (P < 1 × 10-5) with TBRD and HCR1. One locus was associated (P = 8.97 × 10-6) with TBRD on BTA19 and included the positional candidate gene ASIC2, which is differentially expressed in the endometrium of fertility classified heifers, and the positional candidate gene, SPACA3. Gene-set enrichment analyses using SNP (GSEA-SNP) data, was performed and identified one gene-set, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen as enriched (NES = 3.15) with TBRD and contained nine leading edge genes that contributed to the enrichment of the gene set. The enriched gene-set is involved in catalyzing oxidation-reduction reactions, which have been associated with oxidative stressors impacting pregnancy success. No loci were associated nor gene-sets enriched with HCR1. Identification of loci, positional candidate genes, gene-sets and leading edge genes enriched for fertility facilitate genomic selection that allows producers to select for reproductively superior cattle, reduce costs associated with infertility, and increase percent calf crop." @default.
• W3016185930 created "2020-04-17" @default.
• W3016185930 creator A5006590721 @default.
• W3016185930 creator A5012902352 @default.
• W3016185930 creator A5027866784 @default.
• W3016185930 creator A5048797346 @default.
• W3016185930 creator A5057937425 @default.
• W3016185930 creator A5076315257 @default.
• W3016185930 creator A5078461125 @default.
• W3016185930 creator A5081255841 @default.
• W3016185930 date "2020-04-09" @default.
• W3016185930 modified "2023-09-28" @default.
• W3016185930 title "Loci associated with conception rate in crossbred beef heifers" @default.
• W3016185930 cites W1214065317 @default.
• W3016185930 cites W1528925569 @default.
• W3016185930 cites W171819190 @default.
• W3016185930 cites W1828621316 @default.
• W3016185930 cites W1977009443 @default.
• W3016185930 cites W1983612989 @default.
• W3016185930 cites W1984119010 @default.
• W3016185930 cites W1989543998 @default.
• W3016185930 cites W2031305380 @default.
• W3016185930 cites W2035767523 @default.
• W3016185930 cites W2036962858 @default.
• W3016185930 cites W2045914330 @default.
• W3016185930 cites W2046368606 @default.
• W3016185930 cites W2064178384 @default.
• W3016185930 cites W2072082188 @default.
• W3016185930 cites W2072846961 @default.
• W3016185930 cites W2078480738 @default.
• W3016185930 cites W2085862993 @default.
• W3016185930 cites W2086647739 @default.
• W3016185930 cites W2100338186 @default.
• W3016185930 cites W2103017472 @default.
• W3016185930 cites W2104256886 @default.
• W3016185930 cites W2110428682 @default.
• W3016185930 cites W2112750648 @default.
• W3016185930 cites W2122954023 @default.
• W3016185930 cites W2123159984 @default.
• W3016185930 cites W2129589687 @default.
• W3016185930 cites W2131952691 @default.
• W3016185930 cites W2134783591 @default.
• W3016185930 cites W2137089630 @default.
• W3016185930 cites W2139870405 @default.
• W3016185930 cites W2140906896 @default.
• W3016185930 cites W2142003876 @default.
• W3016185930 cites W2142043767 @default.
• W3016185930 cites W2152664025 @default.
• W3016185930 cites W2157752701 @default.
• W3016185930 cites W2158280028 @default.
• W3016185930 cites W2158634391 @default.
• W3016185930 cites W2159220779 @default.
• W3016185930 cites W2161245845 @default.
• W3016185930 cites W2162917469 @default.
• W3016185930 cites W2164135151 @default.
• W3016185930 cites W2772426150 @default.
• W3016185930 cites W2784015829 @default.
• W3016185930 cites W2790798210 @default.
• W3016185930 cites W2950595506 @default.
• W3016185930 cites W87120340 @default.
• W3016185930 doi "https://doi.org/10.1371/journal.pone.0230422" @default.
• W3016185930 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7145093" @default.
• W3016185930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32271764" @default.
• W3016185930 hasPublicationYear "2020" @default.
• W3016185930 type Work @default.
• W3016185930 sameAs 3016185930 @default.
• W3016185930 citedByCount "2" @default.
• W3016185930 countsByYear W30161859302021 @default.
• W3016185930 countsByYear W30161859302022 @default.
• W3016185930 crossrefType "journal-article" @default.
• W3016185930 hasAuthorship W3016185930A5006590721 @default.
• W3016185930 hasAuthorship W3016185930A5012902352 @default.
• W3016185930 hasAuthorship W3016185930A5027866784 @default.
• W3016185930 hasAuthorship W3016185930A5048797346 @default.
• W3016185930 hasAuthorship W3016185930A5057937425 @default.
• W3016185930 hasAuthorship W3016185930A5076315257 @default.
• W3016185930 hasAuthorship W3016185930A5078461125 @default.
• W3016185930 hasAuthorship W3016185930A5081255841 @default.
• W3016185930 hasBestOaLocation W30161859301 @default.
• W3016185930 hasConcept C104317684 @default.
• W3016185930 hasConcept C135763542 @default.
• W3016185930 hasConcept C139275648 @default.
• W3016185930 hasConcept C140793950 @default.
• W3016185930 hasConcept C141231307 @default.
• W3016185930 hasConcept C153209595 @default.
• W3016185930 hasConcept C16685009 @default.
• W3016185930 hasConcept C173419221 @default.
• W3016185930 hasConcept C2776473694 @default.
• W3016185930 hasConcept C2776482104 @default.
• W3016185930 hasConcept C2778610407 @default.
• W3016185930 hasConcept C2779234561 @default.
• W3016185930 hasConcept C2780505807 @default.
• W3016185930 hasConcept C54355233 @default.
• W3016185930 hasConcept C69991583 @default.
• W3016185930 hasConcept C71924100 @default.
• W3016185930 hasConcept C84597430 @default.
• W3016185930 hasConcept C86803240 @default.
• W3016185930 hasConceptScore W3016185930C104317684 @default.

• next