FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016201501> ?p ?o ?g. }

• W3016201501 endingPage "105833" @default.
• W3016201501 startingPage "105833" @default.
• W3016201501 abstract "Parkinson disease (PD), a neurodegenerative disease, has also some immunologic basis in which several regulatory factors, like Helios and Neuropilin-1 (NRP-1) may show some roles in its pathogenesis. We aimed to evaluate the circulatory frequency of T regulatory cells (Tregs) expressing Helios and NRP-1 in PD. In this case-control study, 83 patients with PD and 83 healthy controls were enrolled. The diagnosis of PD was accomplished in accordance with clinical diagnostic criteria of the UK Parkinson Disease Society Brain Bank. The modified Hoehn and Yahr (H and Y) were used to measure the severity of PD. Flow cytometry was used to evaluate the circulatory frequency of CD4+CD25+Foxp3+Tregs expressing and Helios and NRP-1 in all participants. Also, correlation of H and Y with such frequencies was evaluated. Our findings showed that frequency of CD4+CD25+Foxp3+Tregs expressing NRP-1 (P = 0.04) and Helios (P = 0.01) in patients with PD was significantly higher than those in healthy subjects. The frequency of Tregs expressing Helios and NRP-1 showed a negative correlation with H and Y criteria and disease duration. Multiple linear regression analysis indicated that the severity of PD is the only effective factor on the frequency of CD4+CD25+Foxp3+NRP-1+Tregs (P = 0.012) and CD4+CD25+FoxP3+ Helios + Tregs (P = 0.038). Our study showed that the increased frequency of Tregs expressing Helios and NRP-1 is associated with the severity of PD." @default.
• W3016201501 created "2020-04-17" @default.
• W3016201501 creator A5000520896 @default.
• W3016201501 creator A5005380405 @default.
• W3016201501 creator A5007264504 @default.
• W3016201501 creator A5012552801 @default.
• W3016201501 creator A5038027064 @default.
• W3016201501 creator A5079539358 @default.
• W3016201501 creator A5083669582 @default.
• W3016201501 date "2020-05-01" @default.
• W3016201501 modified "2023-09-25" @default.
• W3016201501 title "The correlation of helios and neuropilin-1 frequencies with parkinson disease severity" @default.
• W3016201501 cites W1750903225 @default.
• W3016201501 cites W1753039879 @default.
• W3016201501 cites W1795562300 @default.
• W3016201501 cites W1906467669 @default.
• W3016201501 cites W1967114357 @default.
• W3016201501 cites W1975054545 @default.
• W3016201501 cites W1979594892 @default.
• W3016201501 cites W1982535961 @default.
• W3016201501 cites W1997300044 @default.
• W3016201501 cites W2010794825 @default.
• W3016201501 cites W2020709543 @default.
• W3016201501 cites W2037848690 @default.
• W3016201501 cites W2038470466 @default.
• W3016201501 cites W2052271935 @default.
• W3016201501 cites W2066867563 @default.
• W3016201501 cites W2067817921 @default.
• W3016201501 cites W2073775185 @default.
• W3016201501 cites W2073865791 @default.
• W3016201501 cites W2075663238 @default.
• W3016201501 cites W2086930561 @default.
• W3016201501 cites W2088046822 @default.
• W3016201501 cites W2098732827 @default.
• W3016201501 cites W2099314444 @default.
• W3016201501 cites W2099495167 @default.
• W3016201501 cites W2100314344 @default.
• W3016201501 cites W2102857641 @default.
• W3016201501 cites W2107966431 @default.
• W3016201501 cites W2111260594 @default.
• W3016201501 cites W2111329034 @default.
• W3016201501 cites W2119690971 @default.
• W3016201501 cites W2125295742 @default.
• W3016201501 cites W2126008330 @default.
• W3016201501 cites W2141649011 @default.
• W3016201501 cites W2141722144 @default.
• W3016201501 cites W2141811262 @default.
• W3016201501 cites W2147638016 @default.
• W3016201501 cites W2148592593 @default.
• W3016201501 cites W2152731851 @default.
• W3016201501 cites W2173706022 @default.
• W3016201501 cites W2794421407 @default.
• W3016201501 cites W2807141106 @default.
• W3016201501 cites W2810232847 @default.
• W3016201501 cites W2885873744 @default.
• W3016201501 doi "https://doi.org/10.1016/j.clineuro.2020.105833" @default.
• W3016201501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32305590" @default.
• W3016201501 hasPublicationYear "2020" @default.
• W3016201501 type Work @default.
• W3016201501 sameAs 3016201501 @default.
• W3016201501 citedByCount "4" @default.
• W3016201501 countsByYear W30162015012021 @default.
• W3016201501 countsByYear W30162015012022 @default.
• W3016201501 countsByYear W30162015012023 @default.
• W3016201501 crossrefType "journal-article" @default.
• W3016201501 hasAuthorship W3016201501A5000520896 @default.
• W3016201501 hasAuthorship W3016201501A5005380405 @default.
• W3016201501 hasAuthorship W3016201501A5007264504 @default.
• W3016201501 hasAuthorship W3016201501A5012552801 @default.
• W3016201501 hasAuthorship W3016201501A5038027064 @default.
• W3016201501 hasAuthorship W3016201501A5079539358 @default.
• W3016201501 hasAuthorship W3016201501A5083669582 @default.
• W3016201501 hasConcept C117220453 @default.
• W3016201501 hasConcept C126322002 @default.
• W3016201501 hasConcept C143998085 @default.
• W3016201501 hasConcept C167734588 @default.
• W3016201501 hasConcept C203014093 @default.
• W3016201501 hasConcept C2524010 @default.
• W3016201501 hasConcept C2776090121 @default.
• W3016201501 hasConcept C2777025900 @default.
• W3016201501 hasConcept C2779134260 @default.
• W3016201501 hasConcept C2779727006 @default.
• W3016201501 hasConcept C2779734285 @default.
• W3016201501 hasConcept C2780942790 @default.
• W3016201501 hasConcept C33923547 @default.
• W3016201501 hasConcept C34425596 @default.
• W3016201501 hasConcept C553184892 @default.
• W3016201501 hasConcept C71924100 @default.
• W3016201501 hasConcept C79484868 @default.
• W3016201501 hasConcept C8891405 @default.
• W3016201501 hasConcept C90924648 @default.
• W3016201501 hasConceptScore W3016201501C117220453 @default.
• W3016201501 hasConceptScore W3016201501C126322002 @default.
• W3016201501 hasConceptScore W3016201501C143998085 @default.
• W3016201501 hasConceptScore W3016201501C167734588 @default.
• W3016201501 hasConceptScore W3016201501C203014093 @default.
• W3016201501 hasConceptScore W3016201501C2524010 @default.
• W3016201501 hasConceptScore W3016201501C2776090121 @default.

• next