FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016221019> ?p ?o ?g. }

• W3016221019 endingPage "173098" @default.
• W3016221019 startingPage "173098" @default.
• W3016221019 abstract "Excessive taking fluoride (F) causes severe damage to reproductive system through stimulation of apoptosis and oxidant stress. Selenium (Se) may promote anti-oxidant enzymes and invert cell apoptosis. The aim of this study was to investigate the effect of Se on peripheral blood mononuclear cell (PBMC) apoptosis and oxidant stress in women with fluorosis. Sixty women were divided into three groups according to serum and urine fluoride and hair Se as High F + high Se group, High F group and Control group. The activities of anti-oxidant enzymes, malondialdehyde (MDA) and Se were measured. The levels of sirtuin type 1 (SIRT1), estradiol (E2), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were measured by enzyme-linked immune sorbent assay (ELISA) kits. The expression of protein and apoptosis rate were detected by Western blot and Flow cytometry. The levels of E2, anti-oxidant enzymes in High F group were significantly lower than that in Control group, while the levels of SIRT1 and MDA were significantly higher. The levels of anti-oxidant enzymes and heat shock protein 70 (HSP70) were significantly increased in High Se + high F group while the expression of caspase-3 was significantly increased in high F group. The levels of LH and FSH in serum were significantly increased in High F group and High Se + high F group. Therefore, Se alleviates apoptosis induced by F through improving the expression of HSP70 and reduces oxidative stress by regulating levels of SIRT1 and anti-oxidant enzymes, and the secretion of certain reproductive hormones." @default.
• W3016221019 created "2020-04-17" @default.
• W3016221019 creator A5005469182 @default.
• W3016221019 creator A5012571820 @default.
• W3016221019 creator A5063253432 @default.
• W3016221019 creator A5078871427 @default.
• W3016221019 creator A5079106165 @default.
• W3016221019 date "2020-07-01" @default.
• W3016221019 modified "2023-10-05" @default.
• W3016221019 title "Selenium may suppress peripheral blood mononuclear cell apoptosis by modulating HSP70 and regulate levels of SIRT1 through reproductive hormone secretion and oxidant stress in women suffering fluorosis" @default.
• W3016221019 cites W1977188090 @default.
• W3016221019 cites W1986095785 @default.
• W3016221019 cites W2015921978 @default.
• W3016221019 cites W2021252675 @default.
• W3016221019 cites W2040738529 @default.
• W3016221019 cites W2058393593 @default.
• W3016221019 cites W2088479375 @default.
• W3016221019 cites W2098728374 @default.
• W3016221019 cites W2145640227 @default.
• W3016221019 cites W2181381951 @default.
• W3016221019 cites W2181676711 @default.
• W3016221019 cites W2338225573 @default.
• W3016221019 cites W2766614368 @default.
• W3016221019 cites W2789687467 @default.
• W3016221019 cites W2792256534 @default.
• W3016221019 cites W2794003882 @default.
• W3016221019 cites W2897809283 @default.
• W3016221019 cites W2898963224 @default.
• W3016221019 cites W2903217293 @default.
• W3016221019 cites W2904930119 @default.
• W3016221019 cites W2905398778 @default.
• W3016221019 cites W2911940519 @default.
• W3016221019 cites W2918985478 @default.
• W3016221019 cites W2928631849 @default.
• W3016221019 cites W2940072739 @default.
• W3016221019 cites W2943922648 @default.
• W3016221019 cites W2946410407 @default.
• W3016221019 cites W2952099132 @default.
• W3016221019 cites W2957379363 @default.
• W3016221019 cites W2958098302 @default.
• W3016221019 cites W2961784779 @default.
• W3016221019 cites W2967743497 @default.
• W3016221019 cites W2980865938 @default.
• W3016221019 doi "https://doi.org/10.1016/j.ejphar.2020.173098" @default.
• W3016221019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32275908" @default.
• W3016221019 hasPublicationYear "2020" @default.
• W3016221019 type Work @default.
• W3016221019 sameAs 3016221019 @default.
• W3016221019 citedByCount "11" @default.
• W3016221019 countsByYear W30162210192021 @default.
• W3016221019 countsByYear W30162210192022 @default.
• W3016221019 countsByYear W30162210192023 @default.
• W3016221019 crossrefType "journal-article" @default.
• W3016221019 hasAuthorship W3016221019A5005469182 @default.
• W3016221019 hasAuthorship W3016221019A5012571820 @default.
• W3016221019 hasAuthorship W3016221019A5063253432 @default.
• W3016221019 hasAuthorship W3016221019A5078871427 @default.
• W3016221019 hasAuthorship W3016221019A5079106165 @default.
• W3016221019 hasConcept C104317684 @default.
• W3016221019 hasConcept C126322002 @default.
• W3016221019 hasConcept C134018914 @default.
• W3016221019 hasConcept C137061746 @default.
• W3016221019 hasConcept C185592680 @default.
• W3016221019 hasConcept C190283241 @default.
• W3016221019 hasConcept C202751555 @default.
• W3016221019 hasConcept C205260736 @default.
• W3016221019 hasConcept C2776151105 @default.
• W3016221019 hasConcept C2778401633 @default.
• W3016221019 hasConcept C2778575703 @default.
• W3016221019 hasConcept C55493867 @default.
• W3016221019 hasConcept C68991219 @default.
• W3016221019 hasConcept C71315377 @default.
• W3016221019 hasConcept C71924100 @default.
• W3016221019 hasConcept C86803240 @default.
• W3016221019 hasConceptScore W3016221019C104317684 @default.
• W3016221019 hasConceptScore W3016221019C126322002 @default.
• W3016221019 hasConceptScore W3016221019C134018914 @default.
• W3016221019 hasConceptScore W3016221019C137061746 @default.
• W3016221019 hasConceptScore W3016221019C185592680 @default.
• W3016221019 hasConceptScore W3016221019C190283241 @default.
• W3016221019 hasConceptScore W3016221019C202751555 @default.
• W3016221019 hasConceptScore W3016221019C205260736 @default.
• W3016221019 hasConceptScore W3016221019C2776151105 @default.
• W3016221019 hasConceptScore W3016221019C2778401633 @default.
• W3016221019 hasConceptScore W3016221019C2778575703 @default.
• W3016221019 hasConceptScore W3016221019C55493867 @default.
• W3016221019 hasConceptScore W3016221019C68991219 @default.
• W3016221019 hasConceptScore W3016221019C71315377 @default.
• W3016221019 hasConceptScore W3016221019C71924100 @default.
• W3016221019 hasConceptScore W3016221019C86803240 @default.
• W3016221019 hasFunder F4320321001 @default.
• W3016221019 hasLocation W30162210191 @default.
• W3016221019 hasLocation W30162210192 @default.
• W3016221019 hasOpenAccess W3016221019 @default.
• W3016221019 hasPrimaryLocation W30162210191 @default.
• W3016221019 hasRelatedWork W125774832 @default.
• W3016221019 hasRelatedWork W188720285 @default.
• W3016221019 hasRelatedWork W2066852536 @default.

• next