Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016281881> ?p ?o ?g. }
- W3016281881 endingPage "6146" @default.
- W3016281881 startingPage "6137" @default.
- W3016281881 abstract "Increasing access to the short-lived α-emitting radionuclide astatine-211 (211At) has the potential to advance targeted α-therapeutic treatment of disease and to solve challenges facing the medical community. For example, there are numerous technical needs associated with advancing the use of 211At in targeted α-therapy, e.g., improving 211At chelates, developing more effective 211At targeting, and characterizing in vivo 211At behavior. There is an insufficient understanding of astatine chemistry to support these efforts. The chemistry of astatine is one of the least developed of all elements on the periodic table, owing to its limited supply and short half-life. Increasing access to 211At could help address these issues and advance understanding of 211At chemistry in general. We contribute here an extraction chromatographic processing method that simplifies 211At production in terms of purification. It utilizes the commercially available Pre-Filter resin to rapidly (<1.5 h) isolate 211At from irradiated bismuth targets (Bi decontamination factors ≥876 000), in reasonable yield (68–55%) and in a form that is compatible for subsequent in vivo study. We are excited about the potential of this procedure to address 211At supply and processing/purification problems." @default.
- W3016281881 created "2020-04-24" @default.
- W3016281881 creator A5000161101 @default.
- W3016281881 creator A5004159951 @default.
- W3016281881 creator A5009266851 @default.
- W3016281881 creator A5016805696 @default.
- W3016281881 creator A5031708262 @default.
- W3016281881 creator A5032434259 @default.
- W3016281881 creator A5035608941 @default.
- W3016281881 creator A5036409687 @default.
- W3016281881 creator A5037627801 @default.
- W3016281881 creator A5040733052 @default.
- W3016281881 creator A5041587250 @default.
- W3016281881 creator A5041785050 @default.
- W3016281881 creator A5057672278 @default.
- W3016281881 creator A5060042756 @default.
- W3016281881 creator A5061681849 @default.
- W3016281881 creator A5065659031 @default.
- W3016281881 creator A5072638711 @default.
- W3016281881 creator A5072874908 @default.
- W3016281881 creator A5076322525 @default.
- W3016281881 date "2020-04-17" @default.
- W3016281881 modified "2023-10-12" @default.
- W3016281881 title "A Solid-State Support for Separating Astatine-211 from Bismuth" @default.
- W3016281881 cites W1967335584 @default.
- W3016281881 cites W1973947601 @default.
- W3016281881 cites W1979624352 @default.
- W3016281881 cites W1981476653 @default.
- W3016281881 cites W1982925719 @default.
- W3016281881 cites W1987233672 @default.
- W3016281881 cites W1988436751 @default.
- W3016281881 cites W1994661305 @default.
- W3016281881 cites W2007245918 @default.
- W3016281881 cites W2016787815 @default.
- W3016281881 cites W2019603702 @default.
- W3016281881 cites W2020160653 @default.
- W3016281881 cites W2026733209 @default.
- W3016281881 cites W2036742887 @default.
- W3016281881 cites W2037093510 @default.
- W3016281881 cites W2048623956 @default.
- W3016281881 cites W2055543485 @default.
- W3016281881 cites W2067937093 @default.
- W3016281881 cites W2076211096 @default.
- W3016281881 cites W2080585386 @default.
- W3016281881 cites W2122281753 @default.
- W3016281881 cites W2143818728 @default.
- W3016281881 cites W2161887165 @default.
- W3016281881 cites W2171341874 @default.
- W3016281881 cites W2321927805 @default.
- W3016281881 cites W2335017154 @default.
- W3016281881 cites W2428670966 @default.
- W3016281881 cites W2467018059 @default.
- W3016281881 cites W2486632190 @default.
- W3016281881 cites W2517182935 @default.
- W3016281881 cites W2560507920 @default.
- W3016281881 cites W2562908978 @default.
- W3016281881 cites W2584139559 @default.
- W3016281881 cites W2584800635 @default.
- W3016281881 cites W2701825620 @default.
- W3016281881 cites W2789940608 @default.
- W3016281881 cites W2790312174 @default.
- W3016281881 cites W2790408708 @default.
- W3016281881 cites W2887708843 @default.
- W3016281881 cites W2900369036 @default.
- W3016281881 cites W2906106047 @default.
- W3016281881 cites W2945870813 @default.
- W3016281881 cites W2951408911 @default.
- W3016281881 cites W2981462266 @default.
- W3016281881 cites W2994163612 @default.
- W3016281881 cites W4232069893 @default.
- W3016281881 cites W4247657329 @default.
- W3016281881 cites W4250746212 @default.
- W3016281881 doi "https://doi.org/10.1021/acs.inorgchem.0c00221" @default.
- W3016281881 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32302134" @default.
- W3016281881 hasPublicationYear "2020" @default.
- W3016281881 type Work @default.
- W3016281881 sameAs 3016281881 @default.
- W3016281881 citedByCount "12" @default.
- W3016281881 countsByYear W30162818812020 @default.
- W3016281881 countsByYear W30162818812021 @default.
- W3016281881 countsByYear W30162818812022 @default.
- W3016281881 countsByYear W30162818812023 @default.
- W3016281881 crossrefType "journal-article" @default.
- W3016281881 hasAuthorship W3016281881A5000161101 @default.
- W3016281881 hasAuthorship W3016281881A5004159951 @default.
- W3016281881 hasAuthorship W3016281881A5009266851 @default.
- W3016281881 hasAuthorship W3016281881A5016805696 @default.
- W3016281881 hasAuthorship W3016281881A5031708262 @default.
- W3016281881 hasAuthorship W3016281881A5032434259 @default.
- W3016281881 hasAuthorship W3016281881A5035608941 @default.
- W3016281881 hasAuthorship W3016281881A5036409687 @default.
- W3016281881 hasAuthorship W3016281881A5037627801 @default.
- W3016281881 hasAuthorship W3016281881A5040733052 @default.
- W3016281881 hasAuthorship W3016281881A5041587250 @default.
- W3016281881 hasAuthorship W3016281881A5041785050 @default.
- W3016281881 hasAuthorship W3016281881A5057672278 @default.
- W3016281881 hasAuthorship W3016281881A5060042756 @default.
- W3016281881 hasAuthorship W3016281881A5061681849 @default.