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- W3016318818 abstract "In previously healthy subjects, vulvar ulcers are mostly caused by sexually transmitted microorganisms. Lipschutz’s acute vulvar ulceration, first reported in 1912, is a non-sexually acquired condition characterized by sudden onset of a few genital ulcers. We systematically review presentation, underlying causes, and disease duration of Lipschutz’s ulceration. A comprehensive source of Excerpta Medica, National Library of Medicine, and Web of Science databases was performed. Reports including cases of apparently previously healthy females affected by Lipschutz’s ulceration were selected. A predefined database was used to extract data on demographics, history, clinical and microbiological findings, and treatment. The search disclosed 158 cases. Almost 90% of cases were ≤ 20 years of age and sexually inactive. Lesions were usually one to about three, painful, ≥ 10 mm large, well-delimited, with a fibrinous and necrotic center and a symmetric distribution. Voiding disorders and enlarged inguinal lymph nodes were observed in a large subset of cases. Canker sores were noted in 10% of patients. Lipschutz’s vulvar ulceration occurred concomitantly with an infectious disease in 139 cases. Infectious mononucleosis syndrome (N = 40) was the most frequently detected well-defined infection, followed by mycoplasma species infections (N = 11). The disease resolved after ≤ 3 weeks. Conclusions: Lipschutz’s ulceration mainly affects both sexually inactive and, less frequently, sexually active subjects ≤ 20 years of age, presents with ≤ 3 vulvar ulcers, resolves without recurrences within 3 weeks and is temporarily associated with an infection, most frequently a flu-like illness or an infectious mononucleosis syndrome." @default.
- W3016318818 created "2020-04-24" @default.
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- W3016318818 date "2020-04-15" @default.
- W3016318818 modified "2023-10-16" @default.
- W3016318818 title "Lipschütz’s acute vulvar ulcer: a systematic review" @default.
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- W3016318818 doi "https://doi.org/10.1007/s00431-020-03647-y" @default.
- W3016318818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32296983" @default.
- W3016318818 hasPublicationYear "2020" @default.
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