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• W3016344194 abstract "Multiple health beneficial effects have been shown for inositol hexakisphosphate (IP6) and its parent compound myo-inositol (Ins) in animal and human studies. However, the most striking is their consistent and reproducible anticancer effect, actively investigated and demonstrated in various experimental models during the last decades. Key molecular targets for cancer are PI3K/Akt, MAPK, PKC, AP-1 and NF-κB. Reduced burden of chemotherapy side-effects in cancer patients receiving IP6 alone or in combination with Ins, have been reported. However, modulation of both insulin resistance and cancer by Ins and IP6 have been indicated, and therefore there is a need for specific, randomized clinical trials and further mechanistic studies." @default.
• W3016344194 created "2020-04-24" @default.
• W3016344194 creator A5033071732 @default.
• W3016344194 date "2020-01-01" @default.
• W3016344194 modified "2023-09-26" @default.
• W3016344194 title "Multitarget Activities of Inositol and Inositol Hexakisphosphate" @default.
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• W3016344194 doi "https://doi.org/10.1007/978-3-030-32857-3_15" @default.
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