FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016440810> ?p ?o ?g. }

• W3016440810 endingPage "236" @default.
• W3016440810 startingPage "232" @default.
• W3016440810 abstract "Hennigar, Stephen R., Claire E. Berryman, Alyssa M. Kelley, Bradley J. Anderson, Andrew J. Young, James P. McClung, and Stefan M. Pasiakos. High-altitude acclimatization suppresses hepcidin expression during severe energy deficit. High Alt Med Biol. 21:232–236, 2020. Background: The erythropoietic cells in the bone marrow require iron to synthesize heme for incorporation into hemoglobin. Exposure to hypoxic conditions, such as extended sojourns to high altitude (HA), results in increased erythropoiesis and an increased physiological requirement for iron. In addition to increasing iron requirements, hypoxic conditions suppress appetite and often lead to decreased energy intake. The objective of this study was to determine the combined effects of severe energy deficit and hypoxia on hepcidin and measures of iron status in lowlanders sojourning to HA. Methods: Iron status indicators and hepcidin were determined in 17 healthy male volunteers (mean ± standard deviation, age 23 ± 6 years, body mass index 27 ± 4 kg/m2) fed a controlled diet (12 ± 1.2 mg iron/day) during a 20-day sojourn to 4300 m above sea level. Results: Chronic exposure to HA during severe energy deficit increased hematocrit by 12% (p < 0.01) and decreased serum hepcidin by 37% (p < 0.01) compared with baseline. Ferritin declined by 18% (p = 0.02) and transferrin saturation and soluble transferrin receptor increased by 55% and 83%, respectively (p < 0.01 for both) compared with baseline. Conclusions: HA acclimatization suppresses hepcidin expression to increase iron availability during severe energy deficit. Registered at ClinicalTrials.gov as NCT02731066." @default.
• W3016440810 created "2020-04-24" @default.
• W3016440810 creator A5016274290 @default.
• W3016440810 creator A5018480021 @default.
• W3016440810 creator A5024629053 @default.
• W3016440810 creator A5069762769 @default.
• W3016440810 creator A5073604220 @default.
• W3016440810 creator A5078068456 @default.
• W3016440810 creator A5085243297 @default.
• W3016440810 date "2020-09-01" @default.
• W3016440810 modified "2023-10-11" @default.
• W3016440810 title "High-Altitude Acclimatization Suppresses Hepcidin Expression During Severe Energy Deficit" @default.
• W3016440810 cites W1924847619 @default.
• W3016440810 cites W1978555937 @default.
• W3016440810 cites W1983275366 @default.
• W3016440810 cites W2002636442 @default.
• W3016440810 cites W2006046265 @default.
• W3016440810 cites W2021744317 @default.
• W3016440810 cites W2030204343 @default.
• W3016440810 cites W2039616374 @default.
• W3016440810 cites W2052575235 @default.
• W3016440810 cites W2082300828 @default.
• W3016440810 cites W2090479720 @default.
• W3016440810 cites W2093700476 @default.
• W3016440810 cites W2096260951 @default.
• W3016440810 cites W2099320317 @default.
• W3016440810 cites W2105370709 @default.
• W3016440810 cites W2133200098 @default.
• W3016440810 cites W2146335178 @default.
• W3016440810 cites W2273384137 @default.
• W3016440810 cites W2273760576 @default.
• W3016440810 cites W2330172985 @default.
• W3016440810 cites W2580415908 @default.
• W3016440810 cites W2765719589 @default.
• W3016440810 cites W2791939832 @default.
• W3016440810 cites W2803905253 @default.
• W3016440810 cites W4243766541 @default.
• W3016440810 cites W4249150518 @default.
• W3016440810 doi "https://doi.org/10.1089/ham.2019.0109" @default.
• W3016440810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32316799" @default.
• W3016440810 hasPublicationYear "2020" @default.
• W3016440810 type Work @default.
• W3016440810 sameAs 3016440810 @default.
• W3016440810 citedByCount "7" @default.
• W3016440810 countsByYear W30164408102020 @default.
• W3016440810 countsByYear W30164408102021 @default.
• W3016440810 countsByYear W30164408102023 @default.
• W3016440810 crossrefType "journal-article" @default.
• W3016440810 hasAuthorship W3016440810A5016274290 @default.
• W3016440810 hasAuthorship W3016440810A5018480021 @default.
• W3016440810 hasAuthorship W3016440810A5024629053 @default.
• W3016440810 hasAuthorship W3016440810A5069762769 @default.
• W3016440810 hasAuthorship W3016440810A5073604220 @default.
• W3016440810 hasAuthorship W3016440810A5078068456 @default.
• W3016440810 hasAuthorship W3016440810A5085243297 @default.
• W3016440810 hasConcept C105702510 @default.
• W3016440810 hasConcept C119406331 @default.
• W3016440810 hasConcept C126322002 @default.
• W3016440810 hasConcept C134018914 @default.
• W3016440810 hasConcept C153852466 @default.
• W3016440810 hasConcept C178790620 @default.
• W3016440810 hasConcept C185592680 @default.
• W3016440810 hasConcept C1862650 @default.
• W3016440810 hasConcept C22814914 @default.
• W3016440810 hasConcept C2776140663 @default.
• W3016440810 hasConcept C2776768029 @default.
• W3016440810 hasConcept C2777417653 @default.
• W3016440810 hasConcept C2778248108 @default.
• W3016440810 hasConcept C2778319317 @default.
• W3016440810 hasConcept C2778534260 @default.
• W3016440810 hasConcept C2778917026 @default.
• W3016440810 hasConcept C2779703530 @default.
• W3016440810 hasConcept C2779875672 @default.
• W3016440810 hasConcept C2780959883 @default.
• W3016440810 hasConcept C2781054738 @default.
• W3016440810 hasConcept C32264632 @default.
• W3016440810 hasConcept C540031477 @default.
• W3016440810 hasConcept C59822182 @default.
• W3016440810 hasConcept C71924100 @default.
• W3016440810 hasConcept C7836513 @default.
• W3016440810 hasConcept C8240015 @default.
• W3016440810 hasConcept C86803240 @default.
• W3016440810 hasConceptScore W3016440810C105702510 @default.
• W3016440810 hasConceptScore W3016440810C119406331 @default.
• W3016440810 hasConceptScore W3016440810C126322002 @default.
• W3016440810 hasConceptScore W3016440810C134018914 @default.
• W3016440810 hasConceptScore W3016440810C153852466 @default.
• W3016440810 hasConceptScore W3016440810C178790620 @default.
• W3016440810 hasConceptScore W3016440810C185592680 @default.
• W3016440810 hasConceptScore W3016440810C1862650 @default.
• W3016440810 hasConceptScore W3016440810C22814914 @default.
• W3016440810 hasConceptScore W3016440810C2776140663 @default.
• W3016440810 hasConceptScore W3016440810C2776768029 @default.
• W3016440810 hasConceptScore W3016440810C2777417653 @default.
• W3016440810 hasConceptScore W3016440810C2778248108 @default.
• W3016440810 hasConceptScore W3016440810C2778319317 @default.
• W3016440810 hasConceptScore W3016440810C2778534260 @default.
• W3016440810 hasConceptScore W3016440810C2778917026 @default.

• next