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- W3016735279 abstract "We report for the first time a continuous-flow strategy to execute O-sulfation modification of heparan sulfate (HS) oligosaccharides. A systematic investigation of the influence of the flow parameters on the installation of the sulfate group on glucosamine monosaccharide can aid the development of a comprehensive, quick, and reliable strategy for O-sulfation of HS oligosaccharide precursors. Deprotection of the sulfated heparin intermediates led to the development of a comprehensive biologically inspired oligosaccharide library to understand the crucial structure–function relationship of HS." @default.
- W3016735279 created "2020-04-24" @default.
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- W3016735279 date "2020-04-20" @default.
- W3016735279 modified "2023-10-01" @default.
- W3016735279 title "Continuous-Flow Accelerated Sulfation of Heparan Sulfate Intermediates" @default.
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- W3016735279 doi "https://doi.org/10.1021/acs.orglett.0c00878" @default.
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