Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016783772> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3016783772 endingPage "101748" @default.
- W3016783772 startingPage "101748" @default.
- W3016783772 abstract "The aim of the present work was the preparation and characterization of nanospheres based on antioxidants resveratrol and epigallocatechin gallate useful for site-specific release of resveratrol to breast cancer cells. Nanospheres were prepared via microemulsion technique and were characterized by light scattering, FT-IR spectrophotometry and Electronic Scanning Microscopy. Spherical particles with a diameter of about ~400 nm have been obtained. Resveratrol was then 100% loaded into nanoparticles and its release profile was evaluated by in vitro studies at pH 7.4, in order to simulate the physiological environment, and at pH 6.2 to simulate the tumor environment. Experimental data displayed a slow and continous release of resveratrol from nanoparticles at both pHs. Nanospheres also showed a strong antioxidant activity against lipid peroxidation induced in rat liver microsomal membranes. Finally, the effects of increasing doses of the resveratrol-epigallocatechin gallate based nanospheres on the proliferation and viability of MDA-MB 231 human breast carcinoma cells were evaluated. The data showed a significant reduction of cell survival. In particular, it has been observed that resveratrol loaded microparticles acted more effectively than the empty ones. All the obtained results suggest that these platforms, thanks to their release profile, biocompatibility, antioxidant and antitumor activity, could be a suitable approach for breast cancer treatment and prevention." @default.
- W3016783772 created "2020-04-24" @default.
- W3016783772 creator A5001037825 @default.
- W3016783772 creator A5030059410 @default.
- W3016783772 creator A5074610701 @default.
- W3016783772 creator A5075517808 @default.
- W3016783772 creator A5086524999 @default.
- W3016783772 date "2020-06-01" @default.
- W3016783772 modified "2023-10-14" @default.
- W3016783772 title "Preparation, characterization and in vitro evaluation of resveratrol-loaded nanospheres potentially useful for human breast carcinoma" @default.
- W3016783772 cites W1965593343 @default.
- W3016783772 cites W1968583232 @default.
- W3016783772 cites W1976041621 @default.
- W3016783772 cites W1987081063 @default.
- W3016783772 cites W1990533056 @default.
- W3016783772 cites W2007207787 @default.
- W3016783772 cites W2025638181 @default.
- W3016783772 cites W2032760352 @default.
- W3016783772 cites W2037916694 @default.
- W3016783772 cites W2039543400 @default.
- W3016783772 cites W2058017479 @default.
- W3016783772 cites W2072210671 @default.
- W3016783772 cites W2112479759 @default.
- W3016783772 cites W2117066893 @default.
- W3016783772 cites W2125552828 @default.
- W3016783772 cites W2137634849 @default.
- W3016783772 cites W2150585579 @default.
- W3016783772 cites W2236070174 @default.
- W3016783772 cites W2325384906 @default.
- W3016783772 cites W2559806750 @default.
- W3016783772 cites W2790430623 @default.
- W3016783772 cites W2791241939 @default.
- W3016783772 cites W2799712382 @default.
- W3016783772 cites W2889646458 @default.
- W3016783772 doi "https://doi.org/10.1016/j.jddst.2020.101748" @default.
- W3016783772 hasPublicationYear "2020" @default.
- W3016783772 type Work @default.
- W3016783772 sameAs 3016783772 @default.
- W3016783772 citedByCount "4" @default.
- W3016783772 countsByYear W30167837722021 @default.
- W3016783772 countsByYear W30167837722022 @default.
- W3016783772 countsByYear W30167837722023 @default.
- W3016783772 crossrefType "journal-article" @default.
- W3016783772 hasAuthorship W3016783772A5001037825 @default.
- W3016783772 hasAuthorship W3016783772A5030059410 @default.
- W3016783772 hasAuthorship W3016783772A5074610701 @default.
- W3016783772 hasAuthorship W3016783772A5075517808 @default.
- W3016783772 hasAuthorship W3016783772A5086524999 @default.
- W3016783772 hasConcept C121608353 @default.
- W3016783772 hasConcept C126322002 @default.
- W3016783772 hasConcept C171250308 @default.
- W3016783772 hasConcept C185592680 @default.
- W3016783772 hasConcept C192562407 @default.
- W3016783772 hasConcept C202751555 @default.
- W3016783772 hasConcept C2776816829 @default.
- W3016783772 hasConcept C2780841128 @default.
- W3016783772 hasConcept C2994423619 @default.
- W3016783772 hasConcept C3018521938 @default.
- W3016783772 hasConcept C502942594 @default.
- W3016783772 hasConcept C530470458 @default.
- W3016783772 hasConcept C55493867 @default.
- W3016783772 hasConcept C71924100 @default.
- W3016783772 hasConcept C98274493 @default.
- W3016783772 hasConceptScore W3016783772C121608353 @default.
- W3016783772 hasConceptScore W3016783772C126322002 @default.
- W3016783772 hasConceptScore W3016783772C171250308 @default.
- W3016783772 hasConceptScore W3016783772C185592680 @default.
- W3016783772 hasConceptScore W3016783772C192562407 @default.
- W3016783772 hasConceptScore W3016783772C202751555 @default.
- W3016783772 hasConceptScore W3016783772C2776816829 @default.
- W3016783772 hasConceptScore W3016783772C2780841128 @default.
- W3016783772 hasConceptScore W3016783772C2994423619 @default.
- W3016783772 hasConceptScore W3016783772C3018521938 @default.
- W3016783772 hasConceptScore W3016783772C502942594 @default.
- W3016783772 hasConceptScore W3016783772C530470458 @default.
- W3016783772 hasConceptScore W3016783772C55493867 @default.
- W3016783772 hasConceptScore W3016783772C71924100 @default.
- W3016783772 hasConceptScore W3016783772C98274493 @default.
- W3016783772 hasLocation W30167837721 @default.
- W3016783772 hasOpenAccess W3016783772 @default.
- W3016783772 hasPrimaryLocation W30167837721 @default.
- W3016783772 hasRelatedWork W2044022290 @default.
- W3016783772 hasRelatedWork W2082483539 @default.
- W3016783772 hasRelatedWork W2224825112 @default.
- W3016783772 hasRelatedWork W2357464032 @default.
- W3016783772 hasRelatedWork W2357701734 @default.
- W3016783772 hasRelatedWork W2391951486 @default.
- W3016783772 hasRelatedWork W2899084033 @default.
- W3016783772 hasRelatedWork W2959594825 @default.
- W3016783772 hasRelatedWork W3016783772 @default.
- W3016783772 hasRelatedWork W3173930063 @default.
- W3016783772 hasVolume "57" @default.
- W3016783772 isParatext "false" @default.
- W3016783772 isRetracted "false" @default.
- W3016783772 magId "3016783772" @default.
- W3016783772 workType "article" @default.