Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016862794> ?p ?o ?g. }
- W3016862794 endingPage "118356" @default.
- W3016862794 startingPage "118356" @default.
- W3016862794 abstract "Foods generally contain special ingredients which easily to interact with drugs human intaking, thus affecting drug efficacy and excretion, and even cause adverse reactions. Vitamin C (Vit. C) is abundant in fresh fruits and vegetables. It plays a regulatory role in redox metabolism, and its absence can cause scurvy. Aspirin (ASP) can be used to treat many diseases, is the earliest, common and widely used as antipyretic, analgesic and antirheumatic medicine. Human serum albumin (HSA) is the most abundant protein in vertebrate plasma and has the property of combining and transporting endogenous and exogenous substances. In this paper, the effects of Vit. C on the combination of ASP and HSA were studied by multi-spectra and voltammetric approaches. Fluorescence spectra showed that the quenching mode between Vit. C and HSA is dynamic, and the main binding force is hydrophobic force. The quenching mode between ASP and HSA is static one, and the main binding force is hydrogen bond and van der Waals force. For ternary biological system of (HSA-ASP)-Vit. C, the binding constant decreases compared with HSA-Vit. C system. However, for (HSA-Vit. C)-ASP system, the binding constant does not change when compared with binary system of HSA-ASP. Based on the technology combination of voltammetry, infrared, three-dimensional fluorescence and circular dichroism (CD), it is proved that the existence of ASP will influence the binding process of Vit. C to HSA. It could be concluded that taking Vit. C first doesn't affect the absorption of ASP and may be good for health; in contrast, it is not good to take Vit. C immediately as one have just taken ASP, because the existence of ASP reduce the absorption of Vit. C for human body." @default.
- W3016862794 created "2020-04-24" @default.
- W3016862794 creator A5011238951 @default.
- W3016862794 creator A5023102363 @default.
- W3016862794 creator A5027174353 @default.
- W3016862794 date "2020-08-01" @default.
- W3016862794 modified "2023-09-27" @default.
- W3016862794 title "Interaction between aspirin and vitamin C with human serum albumin as binary and ternary systems" @default.
- W3016862794 cites W1967010177 @default.
- W3016862794 cites W1984461814 @default.
- W3016862794 cites W1988771356 @default.
- W3016862794 cites W1998537649 @default.
- W3016862794 cites W1998876362 @default.
- W3016862794 cites W2058569149 @default.
- W3016862794 cites W2059064782 @default.
- W3016862794 cites W2060101082 @default.
- W3016862794 cites W2068611344 @default.
- W3016862794 cites W2072039459 @default.
- W3016862794 cites W2084977877 @default.
- W3016862794 cites W2120486535 @default.
- W3016862794 cites W2314899186 @default.
- W3016862794 cites W2548898110 @default.
- W3016862794 cites W2555802526 @default.
- W3016862794 cites W2604337791 @default.
- W3016862794 cites W2605705323 @default.
- W3016862794 cites W2605851078 @default.
- W3016862794 cites W2606537295 @default.
- W3016862794 cites W2609553553 @default.
- W3016862794 cites W2620827703 @default.
- W3016862794 cites W2755998523 @default.
- W3016862794 cites W2766298196 @default.
- W3016862794 cites W2767392060 @default.
- W3016862794 cites W2770113841 @default.
- W3016862794 cites W2775720995 @default.
- W3016862794 cites W2777881053 @default.
- W3016862794 cites W2785599148 @default.
- W3016862794 cites W2787446985 @default.
- W3016862794 cites W2793542748 @default.
- W3016862794 cites W2803398429 @default.
- W3016862794 cites W2803438754 @default.
- W3016862794 cites W2808027869 @default.
- W3016862794 cites W2809115143 @default.
- W3016862794 cites W2809667547 @default.
- W3016862794 cites W2811446089 @default.
- W3016862794 cites W2884681145 @default.
- W3016862794 cites W2887903379 @default.
- W3016862794 cites W2889760376 @default.
- W3016862794 cites W2890437692 @default.
- W3016862794 cites W2892222865 @default.
- W3016862794 cites W2895173528 @default.
- W3016862794 cites W2898888009 @default.
- W3016862794 cites W2904387388 @default.
- W3016862794 cites W2945926269 @default.
- W3016862794 cites W2946313636 @default.
- W3016862794 cites W2947104394 @default.
- W3016862794 cites W2949414195 @default.
- W3016862794 cites W2955058060 @default.
- W3016862794 cites W2979697271 @default.
- W3016862794 cites W2995063076 @default.
- W3016862794 cites W987090432 @default.
- W3016862794 doi "https://doi.org/10.1016/j.saa.2020.118356" @default.
- W3016862794 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32325408" @default.
- W3016862794 hasPublicationYear "2020" @default.
- W3016862794 type Work @default.
- W3016862794 sameAs 3016862794 @default.
- W3016862794 citedByCount "15" @default.
- W3016862794 countsByYear W30168627942020 @default.
- W3016862794 countsByYear W30168627942021 @default.
- W3016862794 countsByYear W30168627942022 @default.
- W3016862794 countsByYear W30168627942023 @default.
- W3016862794 crossrefType "journal-article" @default.
- W3016862794 hasAuthorship W3016862794A5011238951 @default.
- W3016862794 hasAuthorship W3016862794A5023102363 @default.
- W3016862794 hasAuthorship W3016862794A5027174353 @default.
- W3016862794 hasConcept C126322002 @default.
- W3016862794 hasConcept C185592680 @default.
- W3016862794 hasConcept C199360897 @default.
- W3016862794 hasConcept C2776125364 @default.
- W3016862794 hasConcept C2776940978 @default.
- W3016862794 hasConcept C2777628954 @default.
- W3016862794 hasConcept C2778597219 @default.
- W3016862794 hasConcept C41008148 @default.
- W3016862794 hasConcept C43617362 @default.
- W3016862794 hasConcept C64452783 @default.
- W3016862794 hasConcept C71924100 @default.
- W3016862794 hasConceptScore W3016862794C126322002 @default.
- W3016862794 hasConceptScore W3016862794C185592680 @default.
- W3016862794 hasConceptScore W3016862794C199360897 @default.
- W3016862794 hasConceptScore W3016862794C2776125364 @default.
- W3016862794 hasConceptScore W3016862794C2776940978 @default.
- W3016862794 hasConceptScore W3016862794C2777628954 @default.
- W3016862794 hasConceptScore W3016862794C2778597219 @default.
- W3016862794 hasConceptScore W3016862794C41008148 @default.
- W3016862794 hasConceptScore W3016862794C43617362 @default.
- W3016862794 hasConceptScore W3016862794C64452783 @default.
- W3016862794 hasConceptScore W3016862794C71924100 @default.
- W3016862794 hasFunder F4320321001 @default.
- W3016862794 hasFunder F4320338083 @default.