Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016866930> ?p ?o ?g. }
- W3016866930 endingPage "2303" @default.
- W3016866930 startingPage "2292" @default.
- W3016866930 abstract "The oxygenated carotenoid zeaxanthin provides numerous benefits to human health due to its antioxidant properties. Especially it is linked to protecting, together with the xanthophyll lutein, the retina in the human eye by filtering harmful blue light thus delaying the progression of age-related macular degeneration (AMD), the most prevalent cause of blindness in developed countries. Despite its high nutritional value, zeaxanthin is less available than other substantial carotenoids in our diet. To solve this shortage, we chose to develop a new food source that would contain a high concentration of natural zeaxanthin. Tomato (Solanum lycopersicum L.) was selected as the target plant since it is the second largest vegetable crop grown worldwide and its fruit characteristically synthesizes and accumulates a high concentration of carotenoids. We employed two genetic approaches in order to enhance zeaxanthin biosynthesis in tomato fruit: a transgenic metabolic engineering and classical genetic breeding. A nontransgenic tomato line, named 'Xantomato', was generated whose fruit accumulated zeaxanthin at a concentration of 39 μg/g fresh weight (or 577 μg/g dry weight), which comprised ca. 50% of total fruit carotenoids compared to zero in the wild type. This is the highest concentration of zeaxanthin reached in a primary crop. Xantomato can potentially increase zeaxanthin availability in the human diet and serve as raw material for industrial applications." @default.
- W3016866930 created "2020-04-24" @default.
- W3016866930 creator A5001930617 @default.
- W3016866930 creator A5010679422 @default.
- W3016866930 creator A5037917578 @default.
- W3016866930 creator A5066274053 @default.
- W3016866930 date "2020-05-11" @default.
- W3016866930 modified "2023-10-17" @default.
- W3016866930 title "Development of zeaxanthin‐rich tomato fruit through genetic manipulations of carotenoid biosynthesis" @default.
- W3016866930 cites W1011757769 @default.
- W3016866930 cites W1783226114 @default.
- W3016866930 cites W1789824814 @default.
- W3016866930 cites W1833550984 @default.
- W3016866930 cites W1866512655 @default.
- W3016866930 cites W1900216307 @default.
- W3016866930 cites W1953530917 @default.
- W3016866930 cites W1970723410 @default.
- W3016866930 cites W1973619403 @default.
- W3016866930 cites W1986204092 @default.
- W3016866930 cites W1988745949 @default.
- W3016866930 cites W1999480156 @default.
- W3016866930 cites W2000781883 @default.
- W3016866930 cites W2006502691 @default.
- W3016866930 cites W2012396824 @default.
- W3016866930 cites W2013340058 @default.
- W3016866930 cites W2015965837 @default.
- W3016866930 cites W2023414760 @default.
- W3016866930 cites W2027125642 @default.
- W3016866930 cites W2028903821 @default.
- W3016866930 cites W2032108741 @default.
- W3016866930 cites W2035801704 @default.
- W3016866930 cites W2035814904 @default.
- W3016866930 cites W2038216806 @default.
- W3016866930 cites W2045839298 @default.
- W3016866930 cites W2047074855 @default.
- W3016866930 cites W2047341849 @default.
- W3016866930 cites W2048745773 @default.
- W3016866930 cites W2053033255 @default.
- W3016866930 cites W2056965254 @default.
- W3016866930 cites W2057889431 @default.
- W3016866930 cites W2064711593 @default.
- W3016866930 cites W2067803801 @default.
- W3016866930 cites W2068836099 @default.
- W3016866930 cites W2069981544 @default.
- W3016866930 cites W2072148082 @default.
- W3016866930 cites W2079880404 @default.
- W3016866930 cites W2082309337 @default.
- W3016866930 cites W2083150532 @default.
- W3016866930 cites W2083223553 @default.
- W3016866930 cites W2092975073 @default.
- W3016866930 cites W2095618654 @default.
- W3016866930 cites W2100110955 @default.
- W3016866930 cites W2100698349 @default.
- W3016866930 cites W2100890076 @default.
- W3016866930 cites W2105040399 @default.
- W3016866930 cites W2105811828 @default.
- W3016866930 cites W2111176625 @default.
- W3016866930 cites W2111312507 @default.
- W3016866930 cites W2114634794 @default.
- W3016866930 cites W2115355589 @default.
- W3016866930 cites W2121269044 @default.
- W3016866930 cites W2124057830 @default.
- W3016866930 cites W2127955486 @default.
- W3016866930 cites W2129993635 @default.
- W3016866930 cites W2130055957 @default.
- W3016866930 cites W2131394161 @default.
- W3016866930 cites W2137062689 @default.
- W3016866930 cites W2144708187 @default.
- W3016866930 cites W2150245091 @default.
- W3016866930 cites W2151833429 @default.
- W3016866930 cites W2153592290 @default.
- W3016866930 cites W2156369261 @default.
- W3016866930 cites W2164412968 @default.
- W3016866930 cites W2170269727 @default.
- W3016866930 cites W2265846640 @default.
- W3016866930 cites W2269545590 @default.
- W3016866930 cites W2338605042 @default.
- W3016866930 cites W2412508897 @default.
- W3016866930 cites W2419255724 @default.
- W3016866930 cites W2499406279 @default.
- W3016866930 cites W2555505279 @default.
- W3016866930 cites W2557156875 @default.
- W3016866930 cites W2576430281 @default.
- W3016866930 cites W2590066172 @default.
- W3016866930 cites W2593221391 @default.
- W3016866930 cites W2746398248 @default.
- W3016866930 cites W2761604622 @default.
- W3016866930 cites W2762059167 @default.
- W3016866930 cites W2789100434 @default.
- W3016866930 cites W2795555262 @default.
- W3016866930 cites W2796351602 @default.
- W3016866930 cites W2797004409 @default.
- W3016866930 cites W2800549213 @default.
- W3016866930 cites W2807102394 @default.
- W3016866930 cites W2808279934 @default.
- W3016866930 cites W2891071640 @default.
- W3016866930 cites W2896748309 @default.
- W3016866930 cites W2909034606 @default.