FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3016931324> ?p ?o ?g. }

• W3016931324 abstract "The natural history of adrenal function in autoimmune Addison disease once diagnosed and treated has not been systematically studied, but several case reports of recovery from established adrenal failure suggest it may not be uniform.To ascertain steroidogenic function in autoimmune Addison disease immediately following diagnosis and during prolonged treatment.We studied peak serum cortisol in response to ACTH1-24 in 20 newly diagnosed autoimmune Addison disease patients at first presentation and then again within a month. We also studied 37 patients with established Addison disease (for between 7 months and 44 years) in a medication-free state, measuring peak serum cortisol responses to ACTH1-24 and the urine LC-MS steroid metabolome.Adrenal steroidogenesis declined rapidly after steroid replacement treatment for newly diagnosed Addison disease was started, with a peak serum cortisol falling from 138 ± 19 nmol/L (SEM) at presentation to 63 ± 13 nmol/L over 4 weeks (P < 0.003).Six of 37 participants (16%) with established Addison disease had detectable serum cortisol and urine glucocorticoid and mineralocorticoid metabolites during repeat testing, indicating variable degrees of residual adrenal function.Autoimmune Addison disease is a heterogeneous condition, showing a rapid decline in adrenal steroidogenesis during the first few weeks following diagnosis, but low-level residual function in a minority of patients, which appears to persist for many years." @default.
• W3016931324 created "2020-04-24" @default.
• W3016931324 creator A5010324154 @default.
• W3016931324 creator A5024961246 @default.
• W3016931324 creator A5027299449 @default.
• W3016931324 creator A5029243250 @default.
• W3016931324 creator A5029347332 @default.
• W3016931324 creator A5031551905 @default.
• W3016931324 creator A5057478856 @default.
• W3016931324 creator A5062436315 @default.
• W3016931324 date "2020-04-17" @default.
• W3016931324 modified "2023-09-24" @default.
• W3016931324 title "Natural History of Adrenal Steroidogenesis in Autoimmune Addison’s Disease Following Diagnosis and Treatment" @default.
• W3016931324 cites W1533729004 @default.
• W3016931324 cites W1915412563 @default.
• W3016931324 cites W1966088769 @default.
• W3016931324 cites W1967987525 @default.
• W3016931324 cites W1991016861 @default.
• W3016931324 cites W1998979804 @default.
• W3016931324 cites W2013533467 @default.
• W3016931324 cites W2034192623 @default.
• W3016931324 cites W2067861852 @default.
• W3016931324 cites W2076802443 @default.
• W3016931324 cites W2081259790 @default.
• W3016931324 cites W2096026597 @default.
• W3016931324 cites W2123534035 @default.
• W3016931324 cites W2139141657 @default.
• W3016931324 cites W2140377757 @default.
• W3016931324 cites W2145106053 @default.
• W3016931324 cites W2157878899 @default.
• W3016931324 cites W2234917292 @default.
• W3016931324 cites W2526261760 @default.
• W3016931324 cites W2795963838 @default.
• W3016931324 cites W2898150437 @default.
• W3016931324 cites W2907576095 @default.
• W3016931324 cites W2944298165 @default.
• W3016931324 cites W2996688478 @default.
• W3016931324 doi "https://doi.org/10.1210/clinem/dgaa187" @default.
• W3016931324 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7250207" @default.
• W3016931324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32300791" @default.
• W3016931324 hasPublicationYear "2020" @default.
• W3016931324 type Work @default.
• W3016931324 sameAs 3016931324 @default.
• W3016931324 citedByCount "7" @default.
• W3016931324 countsByYear W30169313242021 @default.
• W3016931324 countsByYear W30169313242023 @default.
• W3016931324 crossrefType "journal-article" @default.
• W3016931324 hasAuthorship W3016931324A5010324154 @default.
• W3016931324 hasAuthorship W3016931324A5024961246 @default.
• W3016931324 hasAuthorship W3016931324A5027299449 @default.
• W3016931324 hasAuthorship W3016931324A5029243250 @default.
• W3016931324 hasAuthorship W3016931324A5029347332 @default.
• W3016931324 hasAuthorship W3016931324A5031551905 @default.
• W3016931324 hasAuthorship W3016931324A5057478856 @default.
• W3016931324 hasAuthorship W3016931324A5062436315 @default.
• W3016931324 hasBestOaLocation W30169313241 @default.
• W3016931324 hasConcept C126322002 @default.
• W3016931324 hasConcept C134018914 @default.
• W3016931324 hasConcept C2776069600 @default.
• W3016931324 hasConcept C2777817097 @default.
• W3016931324 hasConcept C2778129406 @default.
• W3016931324 hasConcept C2778709874 @default.
• W3016931324 hasConcept C2778720950 @default.
• W3016931324 hasConcept C2778808452 @default.
• W3016931324 hasConcept C2779075594 @default.
• W3016931324 hasConcept C2779134260 @default.
• W3016931324 hasConcept C2780841215 @default.
• W3016931324 hasConcept C3017452174 @default.
• W3016931324 hasConcept C71924100 @default.
• W3016931324 hasConceptScore W3016931324C126322002 @default.
• W3016931324 hasConceptScore W3016931324C134018914 @default.
• W3016931324 hasConceptScore W3016931324C2776069600 @default.
• W3016931324 hasConceptScore W3016931324C2777817097 @default.
• W3016931324 hasConceptScore W3016931324C2778129406 @default.
• W3016931324 hasConceptScore W3016931324C2778709874 @default.
• W3016931324 hasConceptScore W3016931324C2778720950 @default.
• W3016931324 hasConceptScore W3016931324C2778808452 @default.
• W3016931324 hasConceptScore W3016931324C2779075594 @default.
• W3016931324 hasConceptScore W3016931324C2779134260 @default.
• W3016931324 hasConceptScore W3016931324C2780841215 @default.
• W3016931324 hasConceptScore W3016931324C3017452174 @default.
• W3016931324 hasConceptScore W3016931324C71924100 @default.
• W3016931324 hasFunder F4320319990 @default.
• W3016931324 hasLocation W30169313241 @default.
• W3016931324 hasLocation W30169313242 @default.
• W3016931324 hasLocation W30169313243 @default.
• W3016931324 hasLocation W30169313244 @default.
• W3016931324 hasLocation W30169313245 @default.
• W3016931324 hasOpenAccess W3016931324 @default.
• W3016931324 hasPrimaryLocation W30169313241 @default.
• W3016931324 hasRelatedWork W10275352 @default.
• W3016931324 hasRelatedWork W13511278 @default.
• W3016931324 hasRelatedWork W18039782 @default.
• W3016931324 hasRelatedWork W1866679 @default.
• W3016931324 hasRelatedWork W18980706 @default.
• W3016931324 hasRelatedWork W1997298 @default.
• W3016931324 hasRelatedWork W2029404 @default.
• W3016931324 hasRelatedWork W3899222 @default.
• W3016931324 hasRelatedWork W7112692 @default.
• W3016931324 hasRelatedWork W9333447 @default.

• next