FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3017005730> ?p ?o ?g. }

• W3017005730 abstract "Background Berberine, an alkaloid obtained by extraction from Berberis spp., is a botanical that is widely used in the nutraceutical sector to control cholesterol and blood glucose levels. It is also a molecule that is effective in limiting diarrhea due to its multi-factorial properties, including its antimicrobial, gut eubiotic and antisecretive actions, and its ability to slow gut motility. In our routine clinical practice, we have suggested the use of a berberine-based nutraceutical, formulated with melatonin and depolymerized guar gum, to patients affected by functional diarrhea (FD) or by diarrhea-type irritable bowel syndrome (IBS-D). Methods We have therefore retrospectively analyzed the clinical effect of such a nutritional supplement in these two sub-groups of patients. Results Despite the highly pragmatic scheme of our study, our findings strongly confirm the antidiarrheal properties of berberine and recommend its use in some gut functional diseases characterized by frequent evacuation of mushy and/or watery stools. In fact, even after 30 days of treatment, the berberine-based nutritional supplement significantly reduces diarrheal events by 50-70%. After 90 days, this reduction improves to between 70 and 80%, with a reduction of more than 60% in the number of evacuations per week and with more than 50% of treated subjects demonstrating normalized, according to self-reported Bristol Stool Scale categorization, stool consistency. The product is well tolerated and adherence to the proposed therapy is good. Common side effects of the product are flatulence and meteorism, likely due to the acarbose-like berberine effects on gut α-glucosidase. Conclusions Patients, especially those preferring natural therapy, can be successfully treated, when affected by a gut functional disease characterized by diarrhea, by berberine-based products." @default.
• W3017005730 created "2020-04-24" @default.
• W3017005730 creator A5002069396 @default.
• W3017005730 creator A5015311128 @default.
• W3017005730 creator A5045297793 @default.
• W3017005730 creator A5072480911 @default.
• W3017005730 creator A5089328567 @default.
• W3017005730 date "2020-04-01" @default.
• W3017005730 modified "2023-10-16" @default.
• W3017005730 title "Role of a berberine-based nutritional supplement in reducing diarrhea in subjects with functional gastrointestinal disorders" @default.
• W3017005730 cites W1497410973 @default.
• W3017005730 cites W1526961607 @default.
• W3017005730 cites W1556563580 @default.
• W3017005730 cites W1640815631 @default.
• W3017005730 cites W1955985821 @default.
• W3017005730 cites W1964348907 @default.
• W3017005730 cites W1967167260 @default.
• W3017005730 cites W1977370690 @default.
• W3017005730 cites W1980906691 @default.
• W3017005730 cites W2014052475 @default.
• W3017005730 cites W2034330480 @default.
• W3017005730 cites W2043154317 @default.
• W3017005730 cites W2049921929 @default.
• W3017005730 cites W2052863508 @default.
• W3017005730 cites W2055486182 @default.
• W3017005730 cites W2063980733 @default.
• W3017005730 cites W2068708312 @default.
• W3017005730 cites W2086580205 @default.
• W3017005730 cites W2089682944 @default.
• W3017005730 cites W2090218289 @default.
• W3017005730 cites W2090792031 @default.
• W3017005730 cites W2131219479 @default.
• W3017005730 cites W2156286274 @default.
• W3017005730 cites W2170694552 @default.
• W3017005730 cites W2201565652 @default.
• W3017005730 cites W2287079678 @default.
• W3017005730 cites W2504563199 @default.
• W3017005730 cites W2508451196 @default.
• W3017005730 cites W2517160621 @default.
• W3017005730 cites W2517969443 @default.
• W3017005730 cites W2525906202 @default.
• W3017005730 cites W2588347662 @default.
• W3017005730 cites W2604631625 @default.
• W3017005730 cites W2770069383 @default.
• W3017005730 cites W2770717271 @default.
• W3017005730 cites W2796580167 @default.
• W3017005730 doi "https://doi.org/10.23736/s1121-421x.19.02649-7" @default.
• W3017005730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32283882" @default.
• W3017005730 hasPublicationYear "2020" @default.
• W3017005730 type Work @default.
• W3017005730 sameAs 3017005730 @default.
• W3017005730 citedByCount "8" @default.
• W3017005730 countsByYear W30170057302021 @default.
• W3017005730 countsByYear W30170057302022 @default.
• W3017005730 countsByYear W30170057302023 @default.
• W3017005730 crossrefType "journal-article" @default.
• W3017005730 hasAuthorship W3017005730A5002069396 @default.
• W3017005730 hasAuthorship W3017005730A5015311128 @default.
• W3017005730 hasAuthorship W3017005730A5045297793 @default.
• W3017005730 hasAuthorship W3017005730A5072480911 @default.
• W3017005730 hasAuthorship W3017005730A5089328567 @default.
• W3017005730 hasConcept C126322002 @default.
• W3017005730 hasConcept C142724271 @default.
• W3017005730 hasConcept C17857428 @default.
• W3017005730 hasConcept C2775913212 @default.
• W3017005730 hasConcept C2777573665 @default.
• W3017005730 hasConcept C2779802037 @default.
• W3017005730 hasConcept C2780116568 @default.
• W3017005730 hasConcept C556039675 @default.
• W3017005730 hasConcept C71924100 @default.
• W3017005730 hasConcept C90924648 @default.
• W3017005730 hasConcept C98274493 @default.
• W3017005730 hasConceptScore W3017005730C126322002 @default.
• W3017005730 hasConceptScore W3017005730C142724271 @default.
• W3017005730 hasConceptScore W3017005730C17857428 @default.
• W3017005730 hasConceptScore W3017005730C2775913212 @default.
• W3017005730 hasConceptScore W3017005730C2777573665 @default.
• W3017005730 hasConceptScore W3017005730C2779802037 @default.
• W3017005730 hasConceptScore W3017005730C2780116568 @default.
• W3017005730 hasConceptScore W3017005730C556039675 @default.
• W3017005730 hasConceptScore W3017005730C71924100 @default.
• W3017005730 hasConceptScore W3017005730C90924648 @default.
• W3017005730 hasConceptScore W3017005730C98274493 @default.
• W3017005730 hasIssue "1" @default.
• W3017005730 hasLocation W30170057301 @default.
• W3017005730 hasOpenAccess W3017005730 @default.
• W3017005730 hasPrimaryLocation W30170057301 @default.
• W3017005730 hasRelatedWork W1505388101 @default.
• W3017005730 hasRelatedWork W2381429161 @default.
• W3017005730 hasRelatedWork W2384997820 @default.
• W3017005730 hasRelatedWork W2386266856 @default.
• W3017005730 hasRelatedWork W2405657468 @default.
• W3017005730 hasRelatedWork W2417633704 @default.
• W3017005730 hasRelatedWork W2986010109 @default.
• W3017005730 hasRelatedWork W4232113911 @default.
• W3017005730 hasRelatedWork W4253451121 @default.
• W3017005730 hasRelatedWork W4254029160 @default.
• W3017005730 hasVolume "66" @default.
• W3017005730 isParatext "false" @default.
• W3017005730 isRetracted "false" @default.

• next