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- W3017118023 abstract "Predicting responses to acute hypoxia based on physiologic measures at sea level may be valuable in anticipating adverse responses to acute hypoxia. The purpose of this study was to examine the relationships between heart rate variability (HRV) and arterial oxygen desaturation in response to acute hypoxia exposure at rest and during exercise. METHODS 13 subjects (6 male, 7 female) aged 20.6±0.3 years rested in a supine position for 10 min. Average resting HRV and arterial oxygen saturation (%SpO2) were calculated from the last 5 min. A VO2peak test to determine aerobic fitness (44.1±3.0 ml/kg/min) was performed on a stationary cycle at sea level. Subjects also performed a submaximal bike test for 10–15 min at 65% of HRmax achieved during the VO2peak test in normobaric hypoxia equivalent to an altitude of 3500 meters. RESULTS HRV (RMSSD 54.5±5.7) was significantly correlated (r=0.227, P<0.05) to the percent change (9.7±0.7) in %SpO2 from rest (97.4±0.2) to exercise (88.0±0.8) in normobaric hypoxia. CONCLUSIONS HRV at rest appears to be predictive of the degree of arterial desaturation during exercise in hypoxia equivalent to an altitude of 3500 meters. Current wearable technology that can measure HRV could be used to predict potential adverse responses to exercise in hypoxic conditions such as altitude. Support or Funding Information The Doug Morton/Marilyn Brown Endowment for Biomedical Research, The Foundation for Aging Studies and Exercise Science Research, and The Borgenicht Program." @default.
- W3017118023 created "2020-04-24" @default.
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- W3017118023 date "2020-04-01" @default.
- W3017118023 modified "2023-09-26" @default.
- W3017118023 title "Resting Heart Rate Variability at Sea Level Predicts Arterial Desaturation during Acute Exercise in Hypoxia" @default.
- W3017118023 doi "https://doi.org/10.1096/fasebj.2020.34.s1.05857" @default.
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