FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3017124908> ?p ?o ?g. }

• W3017124908 endingPage "335" @default.
• W3017124908 startingPage "335" @default.
• W3017124908 abstract "Ultraviolet A (UVA) is a major factor in skin aging and damage. Antioxidative materials may ameliorate this UV damage. This study investigated the protective properties of N-(4-bromophenethyl) caffeamide (K36H) against UVA-induced skin inflammation, apoptosis and genotoxicity in keratinocytes. The protein expression or biofactor concentration related to UVA-induced skin damage were identified using an enzyme-linked immunosorbent assay and western blotting. K36H reduced UVA-induced intracellular reactive oxygen species generation and increased nuclear factor erythroid 2–related factor 2 translocation into the nucleus to upregulate the expression of heme oxygenase-1, an intrinsic antioxidant enzyme. K36H inhibited UVA-induced activation of extracellular-signal-regulated kinases and c-Jun N-terminal kinases, reduced the overexpression of matrix metalloproteinase (MMP)-1 and MMP-2 and elevated the expression of the metalloproteinase-1 tissue inhibitor. Moreover, K36H inhibited the phosphorylation of c-Jun and downregulated c-Fos expression. K36H attenuated UVA-induced Bax and caspase-3 expression and upregulated antiapoptotic protein B-cell lymphoma 2 expression. K36H reduced UVA-induced DNA damage. K36H also downregulated inducible nitric oxide synthase, cyclooxygenase-2 and interleukin-6 expression as well as the subsequent generation of prostaglandin E2 and nitric oxide. We observed that K36H ameliorated UVA-induced oxidative stress, inflammation, apoptosis and antiphotocarcinogenic activity. K36H can potentially be used for the development of antiphotodamage and antiphotocarcinogenic products." @default.
• W3017124908 created "2020-04-24" @default.
• W3017124908 creator A5013923925 @default.
• W3017124908 creator A5026039526 @default.
• W3017124908 creator A5034975820 @default.
• W3017124908 creator A5035972650 @default.
• W3017124908 creator A5039155376 @default.
• W3017124908 creator A5046619169 @default.
• W3017124908 creator A5063440338 @default.
• W3017124908 creator A5076202792 @default.
• W3017124908 date "2020-04-20" @default.
• W3017124908 modified "2023-10-17" @default.
• W3017124908 title "Protection against Ultraviolet A-Induced Skin Apoptosis and Carcinogenesis through the Oxidative Stress Reduction Effects of N-(4-bromophenethyl) Caffeamide, A Propolis Derivative" @default.
• W3017124908 cites W151914747 @default.
• W3017124908 cites W1536334842 @default.
• W3017124908 cites W1965720406 @default.
• W3017124908 cites W1968398500 @default.
• W3017124908 cites W1971090593 @default.
• W3017124908 cites W1972172786 @default.
• W3017124908 cites W1976127826 @default.
• W3017124908 cites W1977494214 @default.
• W3017124908 cites W1987453246 @default.
• W3017124908 cites W2000936610 @default.
• W3017124908 cites W2004877384 @default.
• W3017124908 cites W2004896936 @default.
• W3017124908 cites W2012159828 @default.
• W3017124908 cites W2016478164 @default.
• W3017124908 cites W2031881118 @default.
• W3017124908 cites W2032935857 @default.
• W3017124908 cites W2038691856 @default.
• W3017124908 cites W2043622965 @default.
• W3017124908 cites W2043759228 @default.
• W3017124908 cites W2045023739 @default.
• W3017124908 cites W2048553024 @default.
• W3017124908 cites W2058927956 @default.
• W3017124908 cites W2061245560 @default.
• W3017124908 cites W2062239159 @default.
• W3017124908 cites W2077049731 @default.
• W3017124908 cites W2094247004 @default.
• W3017124908 cites W2096822241 @default.
• W3017124908 cites W2107353164 @default.
• W3017124908 cites W2109694810 @default.
• W3017124908 cites W2116688544 @default.
• W3017124908 cites W2127624074 @default.
• W3017124908 cites W2131751509 @default.
• W3017124908 cites W2138132897 @default.
• W3017124908 cites W2138271341 @default.
• W3017124908 cites W2140814936 @default.
• W3017124908 cites W2146558971 @default.
• W3017124908 cites W2147290034 @default.
• W3017124908 cites W2152105450 @default.
• W3017124908 cites W2165722578 @default.
• W3017124908 cites W2172627012 @default.
• W3017124908 cites W2563575197 @default.
• W3017124908 cites W2587361973 @default.
• W3017124908 cites W273436280 @default.
• W3017124908 cites W2758274388 @default.
• W3017124908 cites W2907831572 @default.
• W3017124908 cites W2944715262 @default.
• W3017124908 cites W2969489983 @default.
• W3017124908 cites W2972404627 @default.
• W3017124908 cites W2972941903 @default.
• W3017124908 doi "https://doi.org/10.3390/antiox9040335" @default.
• W3017124908 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7222364" @default.
• W3017124908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32326032" @default.
• W3017124908 hasPublicationYear "2020" @default.
• W3017124908 type Work @default.
• W3017124908 sameAs 3017124908 @default.
• W3017124908 citedByCount "9" @default.
• W3017124908 countsByYear W30171249082020 @default.
• W3017124908 countsByYear W30171249082021 @default.
• W3017124908 countsByYear W30171249082022 @default.
• W3017124908 countsByYear W30171249082023 @default.
• W3017124908 crossrefType "journal-article" @default.
• W3017124908 hasAuthorship W3017124908A5013923925 @default.
• W3017124908 hasAuthorship W3017124908A5026039526 @default.
• W3017124908 hasAuthorship W3017124908A5034975820 @default.
• W3017124908 hasAuthorship W3017124908A5035972650 @default.
• W3017124908 hasAuthorship W3017124908A5039155376 @default.
• W3017124908 hasAuthorship W3017124908A5046619169 @default.
• W3017124908 hasAuthorship W3017124908A5063440338 @default.
• W3017124908 hasAuthorship W3017124908A5076202792 @default.
• W3017124908 hasBestOaLocation W30171249081 @default.
• W3017124908 hasConcept C143425029 @default.
• W3017124908 hasConcept C153911025 @default.
• W3017124908 hasConcept C178790620 @default.
• W3017124908 hasConcept C181199279 @default.
• W3017124908 hasConcept C184235292 @default.
• W3017124908 hasConcept C185592680 @default.
• W3017124908 hasConcept C190283241 @default.
• W3017124908 hasConcept C2776151105 @default.
• W3017124908 hasConcept C2776217839 @default.
• W3017124908 hasConcept C2777622882 @default.
• W3017124908 hasConcept C2779219270 @default.
• W3017124908 hasConcept C48349386 @default.
• W3017124908 hasConcept C519581460 @default.
• W3017124908 hasConcept C552990157 @default.
• W3017124908 hasConcept C55493867 @default.

• next