FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3017306571> ?p ?o ?g. }

• W3017306571 endingPage "3368" @default.
• W3017306571 startingPage "3358" @default.
• W3017306571 abstract "Abstract Objectives To investigate criteria for treatment response and remission in patients with axial SpA as assessed by whole-body magnetic resonance imaging (WB-MRI) of axial and peripheral joints and entheses during treatment with golimumab. Methods We performed an investigator-initiated cohort study of 53 patients who underwent WB-MRI at weeks 0, 4, 16 and 52 after initiation of golimumab. Images were assessed according to the Spondyloarthritis Research Consortium of Canada MRI SI joint inflammation index, Canada–Denmark MRI spine inflammation score and the MRI peripheral joints and entheses inflammation index. Results At weeks 4, 16 and 52, WB-MRI demonstrated an at least 50% reduction of MRI inflammation of the sacroiliac joints in 16, 29 and 32 (30%, 55% and 60%) patients, of the spine in 20, 30 and 31 (38%, 57% and 58%) patients and of peripheral joints and entheses in 8, 17 and 15 (15%, 32% and 28%) patients, respectively. The BASDAI50 response was achieved by 29, 31 and 31 (55%, 58% and 58%) patients, while ASDAS clinically important improvement (ASDAS-CII) was achieved by 37, 40 and 34 (70%, 75% and 64%) patients. WB-MRI remission criteria for spine, sacroiliac joints and peripheral joints and entheses were explored; total WB-MRI remission was attained by 2, 6 and 3 (4%, 11% and 6%) patients. At week 16, among 35 patients with an at least 50% reduction in the MRI Axial Inflammation Index (sacroiliac joint and spine inflammation), 29 (83%) achieved BASDAI50 and 35 (100%) achieved ASDAS-CII; among 16 patients with MRI axial inflammation non-response, 14 (88%) were BASDAI50 non-responders and 11 (69%) did not achieve ASDAS-CII. Conclusion WB-MRI demonstrated a significant reduction of inflammation in both the spine, sacroiliac joints and peripheral joints and entheses during golimumab treatment. Few patients achieved total WB-MRI remission. Combining spinal and sacroiliac joint inflammation in an MRI Axial Inflammation Index increased the ability to capture response. Trial registration ClinicalTrials.gov, http://clinicaltrials.gov, NCT02011386." @default.
• W3017306571 created "2020-04-24" @default.
• W3017306571 creator A5001617758 @default.
• W3017306571 creator A5001655196 @default.
• W3017306571 creator A5028102614 @default.
• W3017306571 creator A5031809207 @default.
• W3017306571 creator A5043026941 @default.
• W3017306571 creator A5043141865 @default.
• W3017306571 creator A5059636682 @default.
• W3017306571 creator A5072664936 @default.
• W3017306571 creator A5072805882 @default.
• W3017306571 date "2020-04-20" @default.
• W3017306571 modified "2023-10-14" @default.
• W3017306571 title "Novel whole-body magnetic resonance imaging response and remission criteria document diminished inflammation during golimumab treatment in axial spondyloarthritis" @default.
• W3017306571 cites W1770652604 @default.
• W3017306571 cites W1970210728 @default.
• W3017306571 cites W2021808711 @default.
• W3017306571 cites W2039302547 @default.
• W3017306571 cites W2079392881 @default.
• W3017306571 cites W2092773063 @default.
• W3017306571 cites W2100026316 @default.
• W3017306571 cites W2100137363 @default.
• W3017306571 cites W2101030093 @default.
• W3017306571 cites W2137068168 @default.
• W3017306571 cites W2149782012 @default.
• W3017306571 cites W2156605473 @default.
• W3017306571 cites W2278932593 @default.
• W3017306571 cites W2317920591 @default.
• W3017306571 cites W2474510828 @default.
• W3017306571 cites W2572897530 @default.
• W3017306571 cites W2626892237 @default.
• W3017306571 cites W2724955338 @default.
• W3017306571 cites W2787262638 @default.
• W3017306571 cites W2913901216 @default.
• W3017306571 cites W2932315256 @default.
• W3017306571 cites W2979552390 @default.
• W3017306571 cites W4255613904 @default.
• W3017306571 doi "https://doi.org/10.1093/rheumatology/keaa153" @default.
• W3017306571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32310294" @default.
• W3017306571 hasPublicationYear "2020" @default.
• W3017306571 type Work @default.
• W3017306571 sameAs 3017306571 @default.
• W3017306571 citedByCount "10" @default.
• W3017306571 countsByYear W30173065712021 @default.
• W3017306571 countsByYear W30173065712022 @default.
• W3017306571 countsByYear W30173065712023 @default.
• W3017306571 crossrefType "journal-article" @default.
• W3017306571 hasAuthorship W3017306571A5001617758 @default.
• W3017306571 hasAuthorship W3017306571A5001655196 @default.
• W3017306571 hasAuthorship W3017306571A5028102614 @default.
• W3017306571 hasAuthorship W3017306571A5031809207 @default.
• W3017306571 hasAuthorship W3017306571A5043026941 @default.
• W3017306571 hasAuthorship W3017306571A5043141865 @default.
• W3017306571 hasAuthorship W3017306571A5059636682 @default.
• W3017306571 hasAuthorship W3017306571A5072664936 @default.
• W3017306571 hasAuthorship W3017306571A5072805882 @default.
• W3017306571 hasConcept C126322002 @default.
• W3017306571 hasConcept C126838900 @default.
• W3017306571 hasConcept C141071460 @default.
• W3017306571 hasConcept C143409427 @default.
• W3017306571 hasConcept C174286582 @default.
• W3017306571 hasConcept C2776260265 @default.
• W3017306571 hasConcept C2776914184 @default.
• W3017306571 hasConcept C2777077863 @default.
• W3017306571 hasConcept C2777226972 @default.
• W3017306571 hasConcept C2777402515 @default.
• W3017306571 hasConcept C2777575956 @default.
• W3017306571 hasConcept C2778614933 @default.
• W3017306571 hasConcept C2780105995 @default.
• W3017306571 hasConcept C2780131103 @default.
• W3017306571 hasConcept C2781290027 @default.
• W3017306571 hasConcept C2989005 @default.
• W3017306571 hasConcept C71924100 @default.
• W3017306571 hasConceptScore W3017306571C126322002 @default.
• W3017306571 hasConceptScore W3017306571C126838900 @default.
• W3017306571 hasConceptScore W3017306571C141071460 @default.
• W3017306571 hasConceptScore W3017306571C143409427 @default.
• W3017306571 hasConceptScore W3017306571C174286582 @default.
• W3017306571 hasConceptScore W3017306571C2776260265 @default.
• W3017306571 hasConceptScore W3017306571C2776914184 @default.
• W3017306571 hasConceptScore W3017306571C2777077863 @default.
• W3017306571 hasConceptScore W3017306571C2777226972 @default.
• W3017306571 hasConceptScore W3017306571C2777402515 @default.
• W3017306571 hasConceptScore W3017306571C2777575956 @default.
• W3017306571 hasConceptScore W3017306571C2778614933 @default.
• W3017306571 hasConceptScore W3017306571C2780105995 @default.
• W3017306571 hasConceptScore W3017306571C2780131103 @default.
• W3017306571 hasConceptScore W3017306571C2781290027 @default.
• W3017306571 hasConceptScore W3017306571C2989005 @default.
• W3017306571 hasConceptScore W3017306571C71924100 @default.
• W3017306571 hasIssue "11" @default.
• W3017306571 hasLocation W30173065711 @default.
• W3017306571 hasOpenAccess W3017306571 @default.
• W3017306571 hasPrimaryLocation W30173065711 @default.
• W3017306571 hasRelatedWork W1984820264 @default.
• W3017306571 hasRelatedWork W2073817688 @default.
• W3017306571 hasRelatedWork W2094449140 @default.
• W3017306571 hasRelatedWork W2323502797 @default.

• next