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- W3017332004 abstract "In this study, β-tantalum oxide (β-Ta2O5) thin film was synthesized via magnetron sputtering to improve the surface properties, cytocompatibility and electrochemical stability of titanium. X-ray diffraction analysis confirmed a crystalline orthorhombic phase of Ta2O5 film on the β-Ta2O5 experimental surface. A granular structure with a complex and hierarchical nature was demonstrated by atomic force microscopy. Ta2O5-treated surfaces exhibited greater roughness and hydrophilicity compared with untreated titanium discs (control). Enhanced electrochemical stability in simulated body fluid (pH 7.4) was noted for Ta2O5-treated surfaces wherein higher values of charge transfer resistance, nobler corrosion potential, and lower capacitance, corrosion current density, and corrosion rate values were observed vs untreated control. Real-time monitoring of albumin and fibrinogen proteins adsorption by an electrochemical quartz crystal microbalance disclosed similar protein interactions for control and Ta2O5-treated discs, with higher fibrinogen adsorption rates for Ta2O5-treated surfaces. Cell culture assays (MC3T3-E1 cells) demonstrated that Ta2O5-treated discs featured greater in vitro mineral nodule formation, normal cell morphology and spreading, and increased mRNA levels of runt-related transcription factor 2 (Runx-2), osteocalcin (Ocn), and collagen-1 (Col-1). Therefore, it can be concluded that β-Ta2O5 thin films may be considered a promising strategy to trigger superior long-term stability and biological properties of titanium implants." @default.
- W3017332004 created "2020-04-24" @default.
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- W3017332004 date "2020-08-01" @default.
- W3017332004 modified "2023-10-16" @default.
- W3017332004 title "β-Ta2O5 thin film for implant surface modification triggers superior anti-corrosion performance and cytocompatibility of titanium" @default.
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- W3017332004 doi "https://doi.org/10.1016/j.apsusc.2020.146326" @default.
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