FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3017332314> ?p ?o ?g. }

• W3017332314 endingPage "114578" @default.
• W3017332314 startingPage "114578" @default.
• W3017332314 abstract "As ZnO nanoparticles have been applied in many fields, their biological risks on human health, of course, are worthy of our attention. Whether ZnO NPs have the risk and how colonic cells respond to the invaded ZnO NPs are still unknown. Herein, we evaluated the biological effects of ZnO NPs on colonic mucosal cells by in vitro and in vivo methods. IMCE cells, with APC mutation but phenotypically normal, demonstrated hyperproliferation through activating the CXCR2/NF-κB/STAT3/ERK and AKT pathways when exposed to ZnO NPs for 24 h. Long-term exposure of ZnO NPs resulted in the malignant transformation of IMCE cells, showing the morphological changes, anchorage-independent cell growth ability. Importantly, IMCE cells exposed to ZnO NPs subcutaneously grew and induced tumorigenesis in nude mice. In conclusion, exposure of ZnO NPs could induce malignant transformation of colonic mucosal cells through the CXCR2/NF-κB/STAT3/ERK and AKT pathways. We suggest that it was necessary to consider using the precautionary principle for gastrointestinal contact nanomaterials." @default.
• W3017332314 created "2020-04-24" @default.
• W3017332314 creator A5036278865 @default.
• W3017332314 creator A5046123355 @default.
• W3017332314 creator A5072580570 @default.
• W3017332314 creator A5083191874 @default.
• W3017332314 creator A5086555129 @default.
• W3017332314 date "2020-08-01" @default.
• W3017332314 modified "2023-10-16" @default.
• W3017332314 title "Exposure to low dose ZnO nanoparticles induces hyperproliferation and malignant transformation through activating the CXCR2/NF-κB/STAT3/ERK and AKT pathways in colonic mucosal cells" @default.
• W3017332314 cites W1111852518 @default.
• W3017332314 cites W1928384982 @default.
• W3017332314 cites W1965065360 @default.
• W3017332314 cites W1967243795 @default.
• W3017332314 cites W1972019822 @default.
• W3017332314 cites W1974302097 @default.
• W3017332314 cites W1981467511 @default.
• W3017332314 cites W1988924112 @default.
• W3017332314 cites W1990075727 @default.
• W3017332314 cites W2002003950 @default.
• W3017332314 cites W2006157006 @default.
• W3017332314 cites W2011006339 @default.
• W3017332314 cites W2013844033 @default.
• W3017332314 cites W2034343019 @default.
• W3017332314 cites W2037360063 @default.
• W3017332314 cites W2042339803 @default.
• W3017332314 cites W2044588304 @default.
• W3017332314 cites W2057529331 @default.
• W3017332314 cites W2062429789 @default.
• W3017332314 cites W2065448785 @default.
• W3017332314 cites W2067946594 @default.
• W3017332314 cites W2070004993 @default.
• W3017332314 cites W2071841826 @default.
• W3017332314 cites W2077718313 @default.
• W3017332314 cites W2082335615 @default.
• W3017332314 cites W2084875329 @default.
• W3017332314 cites W2103743864 @default.
• W3017332314 cites W2104025882 @default.
• W3017332314 cites W2105922265 @default.
• W3017332314 cites W2112676306 @default.
• W3017332314 cites W2128223379 @default.
• W3017332314 cites W2135715423 @default.
• W3017332314 cites W2137807778 @default.
• W3017332314 cites W2150939200 @default.
• W3017332314 cites W2151392073 @default.
• W3017332314 cites W2153525022 @default.
• W3017332314 cites W2162744598 @default.
• W3017332314 cites W2190701709 @default.
• W3017332314 cites W2296224453 @default.
• W3017332314 cites W2336232418 @default.
• W3017332314 cites W2415945663 @default.
• W3017332314 cites W2428864015 @default.
• W3017332314 cites W2476931805 @default.
• W3017332314 cites W2511216615 @default.
• W3017332314 cites W2539111687 @default.
• W3017332314 cites W2565156559 @default.
• W3017332314 cites W2577730091 @default.
• W3017332314 cites W2585993922 @default.
• W3017332314 cites W2612583081 @default.
• W3017332314 cites W2767916391 @default.
• W3017332314 cites W2768664509 @default.
• W3017332314 cites W2794680426 @default.
• W3017332314 cites W2811313862 @default.
• W3017332314 cites W2816050627 @default.
• W3017332314 cites W2899606217 @default.
• W3017332314 cites W2901219667 @default.
• W3017332314 cites W2902907173 @default.
• W3017332314 cites W2904592547 @default.
• W3017332314 cites W2911188335 @default.
• W3017332314 cites W2914242141 @default.
• W3017332314 cites W2996787256 @default.
• W3017332314 doi "https://doi.org/10.1016/j.envpol.2020.114578" @default.
• W3017332314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32325249" @default.
• W3017332314 hasPublicationYear "2020" @default.
• W3017332314 type Work @default.
• W3017332314 sameAs 3017332314 @default.
• W3017332314 citedByCount "7" @default.
• W3017332314 countsByYear W30173323142020 @default.
• W3017332314 countsByYear W30173323142021 @default.
• W3017332314 countsByYear W30173323142022 @default.
• W3017332314 countsByYear W30173323142023 @default.
• W3017332314 crossrefType "journal-article" @default.
• W3017332314 hasAuthorship W3017332314A5036278865 @default.
• W3017332314 hasAuthorship W3017332314A5046123355 @default.
• W3017332314 hasAuthorship W3017332314A5072580570 @default.
• W3017332314 hasAuthorship W3017332314A5083191874 @default.
• W3017332314 hasAuthorship W3017332314A5086555129 @default.
• W3017332314 hasConcept C104317684 @default.
• W3017332314 hasConcept C185592680 @default.
• W3017332314 hasConcept C2777730290 @default.
• W3017332314 hasConcept C2778923194 @default.
• W3017332314 hasConcept C31033888 @default.
• W3017332314 hasConcept C502942594 @default.
• W3017332314 hasConcept C55493867 @default.
• W3017332314 hasConcept C555283112 @default.
• W3017332314 hasConcept C57074206 @default.
• W3017332314 hasConcept C62112901 @default.
• W3017332314 hasConcept C62478195 @default.

• next