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- W3017370077 endingPage "1109" @default.
- W3017370077 startingPage "1082" @default.
- W3017370077 abstract "The interplay between nanotechnology and pathogens offers a new quest to fight against human infections. Inspiring from their unique thermal, magnetic, optical, or redox potentials, numerous nanomaterials have been employed for bacterial theranostics. The past decade has seen dramatic progress in the development of various nanoantimicrobials, which demands more focus on their safety assessment. The present review critically discusses the toxicity of nanoantimicrobials and the role of key features, including composition, size, surface charge, loading capability, hydrophobicity/philicity, precise release, and functionalization, that can contribute to modulating the effects on microbes. Moreover, how differences in microbe's structure, biofilm formation, persistence cells, and intracellular pathogens bestow resistance or sensitivity toward nanoantimicrobials is broadly investigated. In extension, the most important types of nanoantimicrobial with clinical prospective and their safety assessment are summarized, and finally, based on available evidence, an insight of the principles in designing safer nanoantimicrobials for overcoming pathogens and future challenges in the field is provided." @default.
- W3017370077 created "2020-04-24" @default.
- W3017370077 creator A5022958666 @default.
- W3017370077 creator A5048010832 @default.
- W3017370077 creator A5055627980 @default.
- W3017370077 creator A5073108451 @default.
- W3017370077 creator A5078707856 @default.
- W3017370077 date "2020-04-17" @default.
- W3017370077 modified "2023-10-17" @default.
- W3017370077 title "Safety Assessment of Nanomaterials for Antimicrobial Applications" @default.
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