Matches in SemOpenAlex for { <https://semopenalex.org/work/W3017405535> ?p ?o ?g. }
- W3017405535 endingPage "175" @default.
- W3017405535 startingPage "165" @default.
- W3017405535 abstract "yeyachun and danshen exist as Chinese patent medicine, Xuemai Tong, and are clearly effective at alleviating liver fibrosis (LF). Previous studies have indicated that triterpenoids from yeyachun (EFT), and phenolic acids from danshen (SMP) are effective in the treatment of LF. The regulation of intestinal flora is an effective method for treating LF. The aim of this study was to investigate the effect of a mixture of EFT and SMP on carbon tetrachloride (CCl4) induced LF. Our results showed the mixture significantly decreased liver damage and fibrosis index, and maintained liver tissue composition, compared to the model group. Moreover, the imbalance of symptoms of intestinal flora was improved. The mixture also caused changes to metabolites of gut flora. Furthermore, the expression of CD68 in liver tissues from the treated groups was significantly decreased when compared to the model group. However, no significant difference was observed from microstructure of gut tissues and LPS concentrations in the serum between mixture treated mice and model mice. This study suggests that the mixture of EFT and SMP had a significant effect on CCl4 induced LF, and the mechanism of this action, at least in part, involved the regulation of intestinal flora and their metabolites." @default.
- W3017405535 created "2020-05-01" @default.
- W3017405535 creator A5020311509 @default.
- W3017405535 creator A5025973535 @default.
- W3017405535 creator A5032850363 @default.
- W3017405535 creator A5041266631 @default.
- W3017405535 creator A5041992274 @default.
- W3017405535 creator A5069831074 @default.
- W3017405535 creator A5085142676 @default.
- W3017405535 creator A5085854173 @default.
- W3017405535 creator A5086154362 @default.
- W3017405535 date "2020-07-01" @default.
- W3017405535 modified "2023-10-17" @default.
- W3017405535 title "Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora" @default.
- W3017405535 cites W1534898911 @default.
- W3017405535 cites W1805542971 @default.
- W3017405535 cites W1824445261 @default.
- W3017405535 cites W1976809932 @default.
- W3017405535 cites W1987563683 @default.
- W3017405535 cites W1989015917 @default.
- W3017405535 cites W1993384315 @default.
- W3017405535 cites W2006898142 @default.
- W3017405535 cites W2024350073 @default.
- W3017405535 cites W2025058399 @default.
- W3017405535 cites W2050560791 @default.
- W3017405535 cites W20724912 @default.
- W3017405535 cites W2094100492 @default.
- W3017405535 cites W2099318800 @default.
- W3017405535 cites W2114304287 @default.
- W3017405535 cites W2117533325 @default.
- W3017405535 cites W2139166152 @default.
- W3017405535 cites W2140259969 @default.
- W3017405535 cites W2146256698 @default.
- W3017405535 cites W2147459138 @default.
- W3017405535 cites W2151898526 @default.
- W3017405535 cites W2268066121 @default.
- W3017405535 cites W2283052220 @default.
- W3017405535 cites W2394780519 @default.
- W3017405535 cites W2501691835 @default.
- W3017405535 cites W2560417471 @default.
- W3017405535 cites W2601782869 @default.
- W3017405535 cites W2613460655 @default.
- W3017405535 cites W2748865886 @default.
- W3017405535 cites W2758938412 @default.
- W3017405535 cites W2766900574 @default.
- W3017405535 cites W2779753586 @default.
- W3017405535 cites W2803040573 @default.
- W3017405535 cites W2803331432 @default.
- W3017405535 cites W2803786373 @default.
- W3017405535 cites W2890606083 @default.
- W3017405535 cites W4255712601 @default.
- W3017405535 doi "https://doi.org/10.1016/j.jphs.2020.04.007" @default.
- W3017405535 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32387002" @default.
- W3017405535 hasPublicationYear "2020" @default.
- W3017405535 type Work @default.
- W3017405535 sameAs 3017405535 @default.
- W3017405535 citedByCount "14" @default.
- W3017405535 countsByYear W30174055352020 @default.
- W3017405535 countsByYear W30174055352021 @default.
- W3017405535 countsByYear W30174055352022 @default.
- W3017405535 countsByYear W30174055352023 @default.
- W3017405535 crossrefType "journal-article" @default.
- W3017405535 hasAuthorship W3017405535A5020311509 @default.
- W3017405535 hasAuthorship W3017405535A5025973535 @default.
- W3017405535 hasAuthorship W3017405535A5032850363 @default.
- W3017405535 hasAuthorship W3017405535A5041266631 @default.
- W3017405535 hasAuthorship W3017405535A5041992274 @default.
- W3017405535 hasAuthorship W3017405535A5069831074 @default.
- W3017405535 hasAuthorship W3017405535A5085142676 @default.
- W3017405535 hasAuthorship W3017405535A5085854173 @default.
- W3017405535 hasAuthorship W3017405535A5086154362 @default.
- W3017405535 hasBestOaLocation W30174055351 @default.
- W3017405535 hasConcept C102124568 @default.
- W3017405535 hasConcept C178790620 @default.
- W3017405535 hasConcept C185592680 @default.
- W3017405535 hasConcept C2777234453 @default.
- W3017405535 hasConcept C2777359374 @default.
- W3017405535 hasConcept C523546767 @default.
- W3017405535 hasConcept C539455810 @default.
- W3017405535 hasConcept C54355233 @default.
- W3017405535 hasConcept C55493867 @default.
- W3017405535 hasConcept C71924100 @default.
- W3017405535 hasConcept C86803240 @default.
- W3017405535 hasConcept C98274493 @default.
- W3017405535 hasConceptScore W3017405535C102124568 @default.
- W3017405535 hasConceptScore W3017405535C178790620 @default.
- W3017405535 hasConceptScore W3017405535C185592680 @default.
- W3017405535 hasConceptScore W3017405535C2777234453 @default.
- W3017405535 hasConceptScore W3017405535C2777359374 @default.
- W3017405535 hasConceptScore W3017405535C523546767 @default.
- W3017405535 hasConceptScore W3017405535C539455810 @default.
- W3017405535 hasConceptScore W3017405535C54355233 @default.
- W3017405535 hasConceptScore W3017405535C55493867 @default.
- W3017405535 hasConceptScore W3017405535C71924100 @default.
- W3017405535 hasConceptScore W3017405535C86803240 @default.
- W3017405535 hasConceptScore W3017405535C98274493 @default.
- W3017405535 hasFunder F4320321001 @default.
- W3017405535 hasIssue "3" @default.