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- W3018196602 abstract "Significance In this study, Kim et al. identify Drosophila CFTR ( dCFTR ) and show that knockdown of dCFTR in the adult intestine disrupts osmotic homeostasis and displays CF-like phenotypes that lead to intestinal stem cell hyperplasia. They show that expression of wild-type human CFTR , but not mutated forms of CFTR that affect protein production or transport, rescues the mutant phenotypes of dCFTR . Furthermore, global transcriptomic analysis of dCFTR fly intestine identified a mucin gene that is required for proper intestinal barrier protection. Altogether, their findings suggest that Drosophila can be a powerful model organism for studying CF pathophysiology." @default.
- W3018196602 created "2020-05-01" @default.
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- W3018196602 date "2020-04-28" @default.
- W3018196602 modified "2023-10-02" @default.
- W3018196602 title "<i>Drosophila</i> as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system" @default.
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- W3018196602 cites W1677736314 @default.
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- W3018196602 cites W1845641771 @default.
- W3018196602 cites W1874411209 @default.
- W3018196602 cites W1940339796 @default.
- W3018196602 cites W1969230606 @default.
- W3018196602 cites W1971149849 @default.
- W3018196602 cites W1971744216 @default.
- W3018196602 cites W1978811535 @default.
- W3018196602 cites W1990877187 @default.
- W3018196602 cites W1996858055 @default.
- W3018196602 cites W1997394341 @default.
- W3018196602 cites W2010691166 @default.
- W3018196602 cites W2013306854 @default.
- W3018196602 cites W2015160508 @default.
- W3018196602 cites W2015357935 @default.
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- W3018196602 cites W2022941489 @default.
- W3018196602 cites W2026100561 @default.
- W3018196602 cites W2027823440 @default.
- W3018196602 cites W2030791386 @default.
- W3018196602 cites W2032605950 @default.
- W3018196602 cites W2033123952 @default.
- W3018196602 cites W2034633897 @default.
- W3018196602 cites W2035386070 @default.
- W3018196602 cites W2036774130 @default.
- W3018196602 cites W2039295111 @default.
- W3018196602 cites W2039599894 @default.
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- W3018196602 cites W2072415775 @default.
- W3018196602 cites W2073091205 @default.
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- W3018196602 cites W2078078890 @default.
- W3018196602 cites W2082916309 @default.
- W3018196602 cites W2086293424 @default.
- W3018196602 cites W2087326716 @default.
- W3018196602 cites W2099222122 @default.
- W3018196602 cites W2099258590 @default.
- W3018196602 cites W2104136593 @default.
- W3018196602 cites W2105039688 @default.
- W3018196602 cites W2106552432 @default.
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- W3018196602 cites W2114670718 @default.
- W3018196602 cites W2117017587 @default.
- W3018196602 cites W2134160513 @default.
- W3018196602 cites W2135363031 @default.
- W3018196602 cites W2136143572 @default.
- W3018196602 cites W2143070723 @default.
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- W3018196602 cites W2147868143 @default.
- W3018196602 cites W2149525061 @default.
- W3018196602 cites W2151563669 @default.
- W3018196602 cites W2152755192 @default.
- W3018196602 cites W2154210643 @default.
- W3018196602 cites W2154335708 @default.
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- W3018196602 cites W2166725749 @default.
- W3018196602 cites W2168424504 @default.
- W3018196602 cites W2169992673 @default.
- W3018196602 cites W2181803248 @default.
- W3018196602 cites W2206135560 @default.
- W3018196602 cites W2262187954 @default.
- W3018196602 cites W2271490085 @default.
- W3018196602 cites W2276029722 @default.
- W3018196602 cites W2287116987 @default.
- W3018196602 cites W2407332505 @default.
- W3018196602 cites W2523894503 @default.
- W3018196602 cites W2564123418 @default.
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- W3018196602 doi "https://doi.org/10.1073/pnas.1913127117" @default.
- W3018196602 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7229672" @default.
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- W3018196602 hasPublicationYear "2020" @default.
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