FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3018498754> ?p ?o ?g. }

• W3018498754 abstract "Background Few data have been published to date on outcomes after the common clinical experience of severe hemorrhage in orally anticoagulated patients. Methods A prospective, multicenter observational study was carried out to investigate outcomes and management in a series of consecutive patients who sustained a severe hemorrhage under treatment with vitamin K antagonists (VKA) or direct oral anticoagulant drugs (DOAC). The primary endpoint was in-hospital death up to and including day 30 after hospital admission. The secondary endpoints were the duration of bleeding, in-hospital death due to hemorrhage (as defined by the study physician examining the patient's records), the use of antagonists, the extent of supportive measures used to stop the hemorrhage, and an assessment of causality. Consecutive patients were recruited until a predefined number of patients was reached in both groups. Results Among 193 patients with severe hemorrhage, 97 had been taking a VKA, and 96 had been taking a DOAC. 13.0 % (95% confidence interval [8.6; 18.5]; 25/193) of the overall group patients died in the first 30 days after hospital admission, including 17.5% ([10.6; 26.6]; 17/97) in the VKA group and 8.3% ([3.7; 15.8]; 8/96) in the DOAC group (p = 0.085). The median duration of bleeding was 19.8 hours in the VKA group and 27.8 hours in the DOAC group (p = 0.632). The in-hospital mortality due to hemorrhage was higher in the VKA group than in the DOAC group (15.5% [15/97] versus 4.2% [4/97]; p = 0.014). Only the use of prothrombin complex concentrates (PCCs) lowered the median duration of hemorrhage in the two patient groups. In 35% (68/193) of the patients, the hemorrhage was caused by an external influence, most commonly a fall. Conclusion The in-hospital mortality was higher among patients treated with VKA than among patients treated with DOAC, although the difference failed to reach statistical significance." @default.
• W3018498754 created "2020-05-01" @default.
• W3018498754 creator A5001586855 @default.
• W3018498754 creator A5004003194 @default.
• W3018498754 creator A5004835573 @default.
• W3018498754 creator A5006384682 @default.
• W3018498754 creator A5017034840 @default.
• W3018498754 creator A5019671722 @default.
• W3018498754 creator A5021929797 @default.
• W3018498754 creator A5029726683 @default.
• W3018498754 creator A5042248757 @default.
• W3018498754 creator A5044191999 @default.
• W3018498754 creator A5053161165 @default.
• W3018498754 creator A5055335269 @default.
• W3018498754 creator A5059317346 @default.
• W3018498754 creator A5065285414 @default.
• W3018498754 creator A5075868354 @default.
• W3018498754 date "2020-05-01" @default.
• W3018498754 modified "2023-10-06" @default.
• W3018498754 title "Severe Hemorrhage Associated With Oral Anticoagulants" @default.
• W3018498754 cites W2018856451 @default.
• W3018498754 cites W2087002320 @default.
• W3018498754 cites W2096246254 @default.
• W3018498754 cites W2097854437 @default.
• W3018498754 cites W2115787552 @default.
• W3018498754 cites W2136489990 @default.
• W3018498754 cites W2152623033 @default.
• W3018498754 cites W2162508946 @default.
• W3018498754 cites W2527161344 @default.
• W3018498754 cites W2554062859 @default.
• W3018498754 cites W2589128497 @default.
• W3018498754 cites W2606132979 @default.
• W3018498754 cites W2612556431 @default.
• W3018498754 cites W2750504927 @default.
• W3018498754 cites W2788664433 @default.
• W3018498754 cites W2792857103 @default.
• W3018498754 cites W2793196115 @default.
• W3018498754 cites W2900643558 @default.
• W3018498754 cites W2908990133 @default.
• W3018498754 cites W2915686929 @default.
• W3018498754 doi "https://doi.org/10.3238/arztebl.2020.0312" @default.
• W3018498754 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7358793" @default.
• W3018498754 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32605708" @default.
• W3018498754 hasPublicationYear "2020" @default.
• W3018498754 type Work @default.
• W3018498754 sameAs 3018498754 @default.
• W3018498754 citedByCount "8" @default.
• W3018498754 countsByYear W30184987542020 @default.
• W3018498754 countsByYear W30184987542021 @default.
• W3018498754 countsByYear W30184987542022 @default.
• W3018498754 crossrefType "journal-article" @default.
• W3018498754 hasAuthorship W3018498754A5001586855 @default.
• W3018498754 hasAuthorship W3018498754A5004003194 @default.
• W3018498754 hasAuthorship W3018498754A5004835573 @default.
• W3018498754 hasAuthorship W3018498754A5006384682 @default.
• W3018498754 hasAuthorship W3018498754A5017034840 @default.
• W3018498754 hasAuthorship W3018498754A5019671722 @default.
• W3018498754 hasAuthorship W3018498754A5021929797 @default.
• W3018498754 hasAuthorship W3018498754A5029726683 @default.
• W3018498754 hasAuthorship W3018498754A5042248757 @default.
• W3018498754 hasAuthorship W3018498754A5044191999 @default.
• W3018498754 hasAuthorship W3018498754A5053161165 @default.
• W3018498754 hasAuthorship W3018498754A5055335269 @default.
• W3018498754 hasAuthorship W3018498754A5059317346 @default.
• W3018498754 hasAuthorship W3018498754A5065285414 @default.
• W3018498754 hasAuthorship W3018498754A5075868354 @default.
• W3018498754 hasBestOaLocation W30184987542 @default.
• W3018498754 hasConcept C126322002 @default.
• W3018498754 hasConcept C17744445 @default.
• W3018498754 hasConcept C177713679 @default.
• W3018498754 hasConcept C199539241 @default.
• W3018498754 hasConcept C2776301958 @default.
• W3018498754 hasConcept C2778810321 @default.
• W3018498754 hasConcept C2779161974 @default.
• W3018498754 hasConcept C2779473830 @default.
• W3018498754 hasConcept C71924100 @default.
• W3018498754 hasConceptScore W3018498754C126322002 @default.
• W3018498754 hasConceptScore W3018498754C17744445 @default.
• W3018498754 hasConceptScore W3018498754C177713679 @default.
• W3018498754 hasConceptScore W3018498754C199539241 @default.
• W3018498754 hasConceptScore W3018498754C2776301958 @default.
• W3018498754 hasConceptScore W3018498754C2778810321 @default.
• W3018498754 hasConceptScore W3018498754C2779161974 @default.
• W3018498754 hasConceptScore W3018498754C2779473830 @default.
• W3018498754 hasConceptScore W3018498754C71924100 @default.
• W3018498754 hasLocation W30184987541 @default.
• W3018498754 hasLocation W30184987542 @default.
• W3018498754 hasLocation W30184987543 @default.
• W3018498754 hasOpenAccess W3018498754 @default.
• W3018498754 hasPrimaryLocation W30184987541 @default.
• W3018498754 hasRelatedWork W1526733470 @default.
• W3018498754 hasRelatedWork W2123087607 @default.
• W3018498754 hasRelatedWork W2320215976 @default.
• W3018498754 hasRelatedWork W2603244127 @default.
• W3018498754 hasRelatedWork W2746504652 @default.
• W3018498754 hasRelatedWork W2952913803 @default.
• W3018498754 hasRelatedWork W3010511938 @default.
• W3018498754 hasRelatedWork W3118338237 @default.
• W3018498754 hasRelatedWork W3149095054 @default.
• W3018498754 hasRelatedWork W3193450048 @default.

• next