Matches in SemOpenAlex for { <https://semopenalex.org/work/W3018506128> ?p ?o ?g. }
- W3018506128 endingPage "10377" @default.
- W3018506128 startingPage "10368" @default.
- W3018506128 abstract "Significance A detailed description of how the genome is organized within the human nucleus is a major research goal. Nucleolar organizer regions (NORs) comprising ribosomal DNA (rDNA) arrays are located on the p-arms of the five human acrocentric chromosomes. Here we characterize the rules of engagement between NORs and nucleoli. We reveal variation in rDNA distribution, with some primary cell lines containing as many as four acrocentrics devoid of rDNA. We establish the default status of NORs as active and show that acrocentric p-arms devoid of rDNA retain nucleolar association potential. Based on our data, we propose that in diploid human cells, all 10 acrocentric chromosomes are nucleolar-associated, with involvement of non-rDNA sequences buffering against variable rDNA distribution." @default.
- W3018506128 created "2020-05-01" @default.
- W3018506128 creator A5031085244 @default.
- W3018506128 creator A5036179656 @default.
- W3018506128 creator A5065040262 @default.
- W3018506128 creator A5066635533 @default.
- W3018506128 date "2020-04-24" @default.
- W3018506128 modified "2023-10-10" @default.
- W3018506128 title "NORs on human acrocentric chromosome p-arms are active by default and can associate with nucleoli independently of rDNA" @default.
- W3018506128 cites W1120562402 @default.
- W3018506128 cites W1974062341 @default.
- W3018506128 cites W1979170620 @default.
- W3018506128 cites W1980652053 @default.
- W3018506128 cites W1992753961 @default.
- W3018506128 cites W2012112380 @default.
- W3018506128 cites W2014598834 @default.
- W3018506128 cites W2019513112 @default.
- W3018506128 cites W2024368545 @default.
- W3018506128 cites W2026226960 @default.
- W3018506128 cites W2072980043 @default.
- W3018506128 cites W2076826746 @default.
- W3018506128 cites W2094401820 @default.
- W3018506128 cites W2098158408 @default.
- W3018506128 cites W2098648205 @default.
- W3018506128 cites W2102462903 @default.
- W3018506128 cites W2108482850 @default.
- W3018506128 cites W2118483219 @default.
- W3018506128 cites W2119606554 @default.
- W3018506128 cites W2121413649 @default.
- W3018506128 cites W2131823236 @default.
- W3018506128 cites W2134222431 @default.
- W3018506128 cites W2140691184 @default.
- W3018506128 cites W2142046859 @default.
- W3018506128 cites W2144591969 @default.
- W3018506128 cites W2144996366 @default.
- W3018506128 cites W2147804306 @default.
- W3018506128 cites W2152674715 @default.
- W3018506128 cites W2158441437 @default.
- W3018506128 cites W2158603579 @default.
- W3018506128 cites W2163527903 @default.
- W3018506128 cites W2169636439 @default.
- W3018506128 cites W2217402320 @default.
- W3018506128 cites W2227837154 @default.
- W3018506128 cites W2476271072 @default.
- W3018506128 cites W2518204360 @default.
- W3018506128 cites W2613778833 @default.
- W3018506128 cites W2694636033 @default.
- W3018506128 cites W2800556562 @default.
- W3018506128 cites W2963104015 @default.
- W3018506128 cites W2986109835 @default.
- W3018506128 doi "https://doi.org/10.1073/pnas.2001812117" @default.
- W3018506128 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7229746" @default.
- W3018506128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32332163" @default.
- W3018506128 hasPublicationYear "2020" @default.
- W3018506128 type Work @default.
- W3018506128 sameAs 3018506128 @default.
- W3018506128 citedByCount "25" @default.
- W3018506128 countsByYear W30185061282020 @default.
- W3018506128 countsByYear W30185061282021 @default.
- W3018506128 countsByYear W30185061282022 @default.
- W3018506128 countsByYear W30185061282023 @default.
- W3018506128 crossrefType "journal-article" @default.
- W3018506128 hasAuthorship W3018506128A5031085244 @default.
- W3018506128 hasAuthorship W3018506128A5036179656 @default.
- W3018506128 hasAuthorship W3018506128A5065040262 @default.
- W3018506128 hasAuthorship W3018506128A5066635533 @default.
- W3018506128 hasBestOaLocation W30185061281 @default.
- W3018506128 hasConcept C104317684 @default.
- W3018506128 hasConcept C143191323 @default.
- W3018506128 hasConcept C183873130 @default.
- W3018506128 hasConcept C184604658 @default.
- W3018506128 hasConcept C190062978 @default.
- W3018506128 hasConcept C207812311 @default.
- W3018506128 hasConcept C30481170 @default.
- W3018506128 hasConcept C54355233 @default.
- W3018506128 hasConcept C63491729 @default.
- W3018506128 hasConcept C67905577 @default.
- W3018506128 hasConcept C86803240 @default.
- W3018506128 hasConcept C90132467 @default.
- W3018506128 hasConceptScore W3018506128C104317684 @default.
- W3018506128 hasConceptScore W3018506128C143191323 @default.
- W3018506128 hasConceptScore W3018506128C183873130 @default.
- W3018506128 hasConceptScore W3018506128C184604658 @default.
- W3018506128 hasConceptScore W3018506128C190062978 @default.
- W3018506128 hasConceptScore W3018506128C207812311 @default.
- W3018506128 hasConceptScore W3018506128C30481170 @default.
- W3018506128 hasConceptScore W3018506128C54355233 @default.
- W3018506128 hasConceptScore W3018506128C63491729 @default.
- W3018506128 hasConceptScore W3018506128C67905577 @default.
- W3018506128 hasConceptScore W3018506128C86803240 @default.
- W3018506128 hasConceptScore W3018506128C90132467 @default.
- W3018506128 hasFunder F4320311904 @default.
- W3018506128 hasIssue "19" @default.
- W3018506128 hasLocation W30185061281 @default.
- W3018506128 hasLocation W30185061282 @default.
- W3018506128 hasLocation W30185061283 @default.
- W3018506128 hasOpenAccess W3018506128 @default.
- W3018506128 hasPrimaryLocation W30185061281 @default.