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- W3019013275 abstract "In vitro generation of insulin-secreting beta cells from human pluripotent stem cells (hPSCs) opens new avenues for treating and modeling diabetes. Hogrebe and colleaguesestablished a new 2D differentiation protocol where they targeted the cytoskeleton pharmacologically for controlled endocrine induction and generation of hPSC-derived beta cells with improved function. In vitro generation of insulin-secreting beta cells from human pluripotent stem cells (hPSCs) opens new avenues for treating and modeling diabetes. Hogrebe and colleaguesestablished a new 2D differentiation protocol where they targeted the cytoskeleton pharmacologically for controlled endocrine induction and generation of hPSC-derived beta cells with improved function." @default.
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- W3019013275 date "2020-06-01" @default.
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- W3019013275 title "Pharmacological Targeting of the Actin Cytoskeleton to Drive Endocrinogenesis" @default.
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- W3019013275 doi "https://doi.org/10.1016/j.tips.2020.04.002" @default.
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