Matches in SemOpenAlex for { <https://semopenalex.org/work/W3019471008> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3019471008 endingPage "104380" @default.
- W3019471008 startingPage "104380" @default.
- W3019471008 abstract "In December of 2019, an outbreak of inexplicable pneumonia cases in several patients appeared in Wuhan, China. What is now known as coronavirus disease 2019 (COVID-19) has spread widely since then and, as of this writing, has infected over 1.8 million people worldwide and has claimed the lives of over 100,000 patients [1]. The disease, COVID-19, is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 has many similarities to SARS-CoV-1 and Middle East respiratory syndrome coronavirus (MERS-CoV), both of which have also been fatal [2]. The number of cases of COVID-19 continues to increase but there is not an approved vaccine or medication that can be used for treatment. Thus, there is an immense need for treatment strategies to help combat this contagious disease. In previous studies, severe patients that have been hospitalized for COVID-19 have had laboratory results that show an increased level of cytokines, specifically interleukin 6 (IL-6) [3]. This increase may be attributed to the cytokine release syndrome (CRS) that is triggered by a variety of factors such as infections [4]. Since IL-6 plays an important role in CRS, it serves as a possible mechanism of treatment in severe patients. Tocilizumab (TCZ) is a recombinant humanized monoclonal antibody that has an antagonist effect on the IL-6 receptor. It is currently used in the treatment of rheumatoid arthritis, but could also play a key role in treatment for severely ill patients with COVID-19. We performed a systematic review to evaluate outcomes associated with TCZ treatment in patients with COVID-19." @default.
- W3019471008 created "2020-05-01" @default.
- W3019471008 creator A5013036005 @default.
- W3019471008 creator A5031151469 @default.
- W3019471008 date "2020-06-01" @default.
- W3019471008 modified "2023-10-17" @default.
- W3019471008 title "Supportive Treatment with Tocilizumab for COVID-19: A Systematic Review" @default.
- W3019471008 cites W2620710772 @default.
- W3019471008 cites W2808166290 @default.
- W3019471008 cites W3007940623 @default.
- W3019471008 cites W3013524951 @default.
- W3019471008 cites W3013789297 @default.
- W3019471008 cites W3014050022 @default.
- W3019471008 cites W3014270994 @default.
- W3019471008 cites W3014306106 @default.
- W3019471008 cites W3014333693 @default.
- W3019471008 cites W3014778376 @default.
- W3019471008 doi "https://doi.org/10.1016/j.jcv.2020.104380" @default.
- W3019471008 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7194791" @default.
- W3019471008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32353761" @default.
- W3019471008 hasPublicationYear "2020" @default.
- W3019471008 type Work @default.
- W3019471008 sameAs 3019471008 @default.
- W3019471008 citedByCount "122" @default.
- W3019471008 countsByYear W30194710082020 @default.
- W3019471008 countsByYear W30194710082021 @default.
- W3019471008 countsByYear W30194710082022 @default.
- W3019471008 countsByYear W30194710082023 @default.
- W3019471008 crossrefType "journal-article" @default.
- W3019471008 hasAuthorship W3019471008A5013036005 @default.
- W3019471008 hasAuthorship W3019471008A5031151469 @default.
- W3019471008 hasBestOaLocation W30194710081 @default.
- W3019471008 hasConcept C116675565 @default.
- W3019471008 hasConcept C126322002 @default.
- W3019471008 hasConcept C159047783 @default.
- W3019471008 hasConcept C177713679 @default.
- W3019471008 hasConcept C2777178219 @default.
- W3019471008 hasConcept C2778137277 @default.
- W3019471008 hasConcept C2779134260 @default.
- W3019471008 hasConcept C2779473830 @default.
- W3019471008 hasConcept C2909376813 @default.
- W3019471008 hasConcept C3006700255 @default.
- W3019471008 hasConcept C3007834351 @default.
- W3019471008 hasConcept C3008058167 @default.
- W3019471008 hasConcept C524204448 @default.
- W3019471008 hasConcept C55493867 @default.
- W3019471008 hasConcept C71924100 @default.
- W3019471008 hasConcept C86803240 @default.
- W3019471008 hasConceptScore W3019471008C116675565 @default.
- W3019471008 hasConceptScore W3019471008C126322002 @default.
- W3019471008 hasConceptScore W3019471008C159047783 @default.
- W3019471008 hasConceptScore W3019471008C177713679 @default.
- W3019471008 hasConceptScore W3019471008C2777178219 @default.
- W3019471008 hasConceptScore W3019471008C2778137277 @default.
- W3019471008 hasConceptScore W3019471008C2779134260 @default.
- W3019471008 hasConceptScore W3019471008C2779473830 @default.
- W3019471008 hasConceptScore W3019471008C2909376813 @default.
- W3019471008 hasConceptScore W3019471008C3006700255 @default.
- W3019471008 hasConceptScore W3019471008C3007834351 @default.
- W3019471008 hasConceptScore W3019471008C3008058167 @default.
- W3019471008 hasConceptScore W3019471008C524204448 @default.
- W3019471008 hasConceptScore W3019471008C55493867 @default.
- W3019471008 hasConceptScore W3019471008C71924100 @default.
- W3019471008 hasConceptScore W3019471008C86803240 @default.
- W3019471008 hasLocation W30194710081 @default.
- W3019471008 hasLocation W30194710082 @default.
- W3019471008 hasLocation W30194710083 @default.
- W3019471008 hasOpenAccess W3019471008 @default.
- W3019471008 hasPrimaryLocation W30194710081 @default.
- W3019471008 hasRelatedWork W3003901880 @default.
- W3019471008 hasRelatedWork W3004826915 @default.
- W3019471008 hasRelatedWork W3005417802 @default.
- W3019471008 hasRelatedWork W3007868867 @default.
- W3019471008 hasRelatedWork W3009669391 @default.
- W3019471008 hasRelatedWork W3020699490 @default.
- W3019471008 hasRelatedWork W3031607536 @default.
- W3019471008 hasRelatedWork W3087206508 @default.
- W3019471008 hasRelatedWork W4206419631 @default.
- W3019471008 hasRelatedWork W3127156785 @default.
- W3019471008 hasVolume "127" @default.
- W3019471008 isParatext "false" @default.
- W3019471008 isRetracted "false" @default.
- W3019471008 magId "3019471008" @default.
- W3019471008 workType "article" @default.