FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3019774328> ?p ?o ?g. }

• W3019774328 endingPage "13467" @default.
• W3019774328 startingPage "13463" @default.
• W3019774328 abstract "Abstract The interaction in multisubunit non‐ribosomal peptide synthetases (NRPSs) is mediated by docking domains that ensure the correct subunit‐to‐subunit interaction. We introduced natural docking domains into the three‐module xefoampeptide synthetase (XfpS) to create two to three artificial NRPS XfpS subunits. The enzymatic performance of the split biosynthesis was measured by absolute quantification of the products by HPLC‐ESI‐MS. The connecting role of the docking domains was probed by deleting integral parts of them. The peptide production data was compared to soluble protein amounts of the NRPS using SDS‐PAGE. Reduced peptide synthesis was not a result of reduced soluble NRPS concentration but a consequence of the deletion of vital docking domain parts. Splitting the xefoampeptide biosynthesis polypeptide by introducing docking domains was feasible and resulted in higher amounts of product in one of the two tested split‐module cases compared to the full‐length wild‐type enzyme." @default.
• W3019774328 created "2020-05-01" @default.
• W3019774328 creator A5028638969 @default.
• W3019774328 creator A5061394829 @default.
• W3019774328 date "2020-05-27" @default.
• W3019774328 modified "2023-10-18" @default.
• W3019774328 title "Artificial Splitting of a Non‐Ribosomal Peptide Synthetase by Inserting Natural Docking Domains" @default.
• W3019774328 cites W1979247338 @default.
• W3019774328 cites W1990123934 @default.
• W3019774328 cites W1990244468 @default.
• W3019774328 cites W1990812439 @default.
• W3019774328 cites W2023650832 @default.
• W3019774328 cites W2033196044 @default.
• W3019774328 cites W2054805269 @default.
• W3019774328 cites W2067779211 @default.
• W3019774328 cites W2070305972 @default.
• W3019774328 cites W2073531367 @default.
• W3019774328 cites W2079251921 @default.
• W3019774328 cites W2087337802 @default.
• W3019774328 cites W2102992442 @default.
• W3019774328 cites W2120777369 @default.
• W3019774328 cites W2128152661 @default.
• W3019774328 cites W2131435066 @default.
• W3019774328 cites W2132924229 @default.
• W3019774328 cites W2136225589 @default.
• W3019774328 cites W2145153665 @default.
• W3019774328 cites W2149695994 @default.
• W3019774328 cites W2157913328 @default.
• W3019774328 cites W2158966280 @default.
• W3019774328 cites W2169595886 @default.
• W3019774328 cites W2225804582 @default.
• W3019774328 cites W2259283565 @default.
• W3019774328 cites W2519331561 @default.
• W3019774328 cites W2539120256 @default.
• W3019774328 cites W2600438420 @default.
• W3019774328 cites W2602946330 @default.
• W3019774328 cites W2772427550 @default.
• W3019774328 cites W2885391792 @default.
• W3019774328 cites W2922438357 @default.
• W3019774328 cites W2951089481 @default.
• W3019774328 cites W2974684084 @default.
• W3019774328 cites W2983327530 @default.
• W3019774328 cites W3012071362 @default.
• W3019774328 cites W4206723357 @default.
• W3019774328 cites W4248230404 @default.
• W3019774328 cites W4256519993 @default.
• W3019774328 doi "https://doi.org/10.1002/anie.201915989" @default.
• W3019774328 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7496407" @default.
• W3019774328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32329545" @default.
• W3019774328 hasPublicationYear "2020" @default.
• W3019774328 type Work @default.
• W3019774328 sameAs 3019774328 @default.
• W3019774328 citedByCount "23" @default.
• W3019774328 countsByYear W30197743282020 @default.
• W3019774328 countsByYear W30197743282021 @default.
• W3019774328 countsByYear W30197743282022 @default.
• W3019774328 countsByYear W30197743282023 @default.
• W3019774328 crossrefType "journal-article" @default.
• W3019774328 hasAuthorship W3019774328A5028638969 @default.
• W3019774328 hasAuthorship W3019774328A5061394829 @default.
• W3019774328 hasBestOaLocation W30197743281 @default.
• W3019774328 hasConcept C104292427 @default.
• W3019774328 hasConcept C104317684 @default.
• W3019774328 hasConcept C159110408 @default.
• W3019774328 hasConcept C181199279 @default.
• W3019774328 hasConcept C185592680 @default.
• W3019774328 hasConcept C21951064 @default.
• W3019774328 hasConcept C2779281246 @default.
• W3019774328 hasConcept C41685203 @default.
• W3019774328 hasConcept C553450214 @default.
• W3019774328 hasConcept C55493867 @default.
• W3019774328 hasConcept C67905577 @default.
• W3019774328 hasConcept C71240020 @default.
• W3019774328 hasConcept C71924100 @default.
• W3019774328 hasConceptScore W3019774328C104292427 @default.
• W3019774328 hasConceptScore W3019774328C104317684 @default.
• W3019774328 hasConceptScore W3019774328C159110408 @default.
• W3019774328 hasConceptScore W3019774328C181199279 @default.
• W3019774328 hasConceptScore W3019774328C185592680 @default.
• W3019774328 hasConceptScore W3019774328C21951064 @default.
• W3019774328 hasConceptScore W3019774328C2779281246 @default.
• W3019774328 hasConceptScore W3019774328C41685203 @default.
• W3019774328 hasConceptScore W3019774328C553450214 @default.
• W3019774328 hasConceptScore W3019774328C55493867 @default.
• W3019774328 hasConceptScore W3019774328C67905577 @default.
• W3019774328 hasConceptScore W3019774328C71240020 @default.
• W3019774328 hasConceptScore W3019774328C71924100 @default.
• W3019774328 hasIssue "32" @default.
• W3019774328 hasLocation W30197743281 @default.
• W3019774328 hasLocation W30197743282 @default.
• W3019774328 hasLocation W30197743283 @default.
• W3019774328 hasOpenAccess W3019774328 @default.
• W3019774328 hasPrimaryLocation W30197743281 @default.
• W3019774328 hasRelatedWork W107896380 @default.
• W3019774328 hasRelatedWork W1550996414 @default.
• W3019774328 hasRelatedWork W1570438659 @default.
• W3019774328 hasRelatedWork W169735115 @default.
• W3019774328 hasRelatedWork W2041074211 @default.

• next