FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3019849260> ?p ?o ?g. }

• W3019849260 endingPage "654" @default.
• W3019849260 startingPage "648" @default.
• W3019849260 abstract "The rapid spread of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an ongoing pandemic of coronavirus disease 2019 (COVID-19). Recently, angiotensin-converting enzyme 2 (ACE2) has been shown to be a functional receptor for SARS-CoV-2 to enter host target cells. Given that angiotensin receptor blockers (ARBs) and an ACE inhibitor (ACEI) upregulated ACE2 expression in animal studies, the concern might arise regarding whether ARBs and ACEIs would increase the morbidity and mortality of COVID-19. On the other hand, animal data suggested a potential protective effect of ARBs against COVID-19 pneumonia because an ARB prevented the aggravation of acute lung injury in mice infected with SARS-CoV, which is closely related to SARS-CoV-2. Importantly, however, there is no clinical or experimental evidence supporting that ARBs and ACEIs either augment the susceptibility to SARS-CoV-2 or aggravate the severity and outcomes of COVID-19 at present. Until further data are available, it is recommended that ARB and ACEI medications be continued for the treatment of patients with cardiovascular disease and hypertension, especially those at high risk, according to guideline-directed medical therapy based on the currently available evidence." @default.
• W3019849260 created "2020-05-01" @default.
• W3019849260 creator A5019621072 @default.
• W3019849260 creator A5075719256 @default.
• W3019849260 date "2020-04-27" @default.
• W3019849260 modified "2023-10-11" @default.
• W3019849260 title "Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19" @default.
• W3019849260 cites W1964982019 @default.
• W3019849260 cites W1966238900 @default.
• W3019849260 cites W1978525739 @default.
• W3019849260 cites W1997832988 @default.
• W3019849260 cites W2008076845 @default.
• W3019849260 cites W2012289331 @default.
• W3019849260 cites W2028521865 @default.
• W3019849260 cites W2033190476 @default.
• W3019849260 cites W2037033420 @default.
• W3019849260 cites W2040717081 @default.
• W3019849260 cites W2045397597 @default.
• W3019849260 cites W2049521850 @default.
• W3019849260 cites W2066073474 @default.
• W3019849260 cites W2066971442 @default.
• W3019849260 cites W2070409286 @default.
• W3019849260 cites W2091671824 @default.
• W3019849260 cites W2118638261 @default.
• W3019849260 cites W2141108790 @default.
• W3019849260 cites W2144370633 @default.
• W3019849260 cites W2158922816 @default.
• W3019849260 cites W2167384912 @default.
• W3019849260 cites W2395642529 @default.
• W3019849260 cites W2745004652 @default.
• W3019849260 cites W2780715796 @default.
• W3019849260 cites W2966611464 @default.
• W3019849260 cites W3001118548 @default.
• W3019849260 cites W3004280078 @default.
• W3019849260 cites W3005655936 @default.
• W3019849260 cites W3007626557 @default.
• W3019849260 cites W3008028633 @default.
• W3019849260 cites W3008827533 @default.
• W3019849260 cites W3009335299 @default.
• W3019849260 cites W3009885589 @default.
• W3019849260 cites W3009912996 @default.
• W3019849260 cites W3009941720 @default.
• W3019849260 cites W3010580363 @default.
• W3019849260 cites W3011862945 @default.
• W3019849260 cites W3012454642 @default.
• W3019849260 cites W3012725239 @default.
• W3019849260 cites W3012771079 @default.
• W3019849260 cites W3013302817 @default.
• W3019849260 cites W3014001472 @default.
• W3019849260 doi "https://doi.org/10.1038/s41440-020-0455-8" @default.
• W3019849260 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7184165" @default.
• W3019849260 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32341442" @default.
• W3019849260 hasPublicationYear "2020" @default.
• W3019849260 type Work @default.
• W3019849260 sameAs 3019849260 @default.
• W3019849260 citedByCount "299" @default.
• W3019849260 countsByYear W30198492602020 @default.
• W3019849260 countsByYear W30198492602021 @default.
• W3019849260 countsByYear W30198492602022 @default.
• W3019849260 countsByYear W30198492602023 @default.
• W3019849260 crossrefType "journal-article" @default.
• W3019849260 hasAuthorship W3019849260A5019621072 @default.
• W3019849260 hasAuthorship W3019849260A5075719256 @default.
• W3019849260 hasBestOaLocation W30198492601 @default.
• W3019849260 hasConcept C126322002 @default.
• W3019849260 hasConcept C170493617 @default.
• W3019849260 hasConcept C198710026 @default.
• W3019849260 hasConcept C203014093 @default.
• W3019849260 hasConcept C2775946041 @default.
• W3019849260 hasConcept C2777648638 @default.
• W3019849260 hasConcept C2777914695 @default.
• W3019849260 hasConcept C2778137277 @default.
• W3019849260 hasConcept C2779134260 @default.
• W3019849260 hasConcept C2908929049 @default.
• W3019849260 hasConcept C2910553456 @default.
• W3019849260 hasConcept C3007834351 @default.
• W3019849260 hasConcept C3008058167 @default.
• W3019849260 hasConcept C524204448 @default.
• W3019849260 hasConcept C71924100 @default.
• W3019849260 hasConcept C84393581 @default.
• W3019849260 hasConcept C89623803 @default.
• W3019849260 hasConceptScore W3019849260C126322002 @default.
• W3019849260 hasConceptScore W3019849260C170493617 @default.
• W3019849260 hasConceptScore W3019849260C198710026 @default.
• W3019849260 hasConceptScore W3019849260C203014093 @default.
• W3019849260 hasConceptScore W3019849260C2775946041 @default.
• W3019849260 hasConceptScore W3019849260C2777648638 @default.
• W3019849260 hasConceptScore W3019849260C2777914695 @default.
• W3019849260 hasConceptScore W3019849260C2778137277 @default.
• W3019849260 hasConceptScore W3019849260C2779134260 @default.
• W3019849260 hasConceptScore W3019849260C2908929049 @default.
• W3019849260 hasConceptScore W3019849260C2910553456 @default.
• W3019849260 hasConceptScore W3019849260C3007834351 @default.
• W3019849260 hasConceptScore W3019849260C3008058167 @default.
• W3019849260 hasConceptScore W3019849260C524204448 @default.
• W3019849260 hasConceptScore W3019849260C71924100 @default.
• W3019849260 hasConceptScore W3019849260C84393581 @default.
• W3019849260 hasConceptScore W3019849260C89623803 @default.

• next