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• W3019861629 abstract "This study aimed to find the effect of antiplatelet therapy on hematoma volume, rehaemorrhage rate and prognosis of intracerebral hemorrhage patients after surgery. 101 surgically treated intracerebral hemorrhage subjects were included and analyzed retrospectively. Prior antiplatelet therapy was ascertained from the clinical history, and the patients included were divided into two groups: antiplatelet therapy and no antiplatelet therapy group. The in-hospital and follow-up outcomes were assessed with the Modified Rankin Scale and were compared between the 2 groups after 1:2 propensity score matching. Before the diagnosis of intracerebral hemorrhage, 21.8 % patients were not on antiplatelet therapy. Antiplatelet therapy group had larger hematoma volume (99.32 mL versus 73.75 mL) with no significant difference (P = 0.308). After propensity score matching, 42 patients were obtained. 4(9.5 %) had rehaemorrhage after surgery, and antiplatelet therapy was not related to higher rehaemorrhage rate (P = 0.628). After follow-up, the overall mortality was 29.3 %, and 22 patients (53.7 %) ended up with severe morbidity. In the multivariate regression, plasma fibrinogen was an independent predictor of both in-hospital and follow-up overall mortality (P = 0.044; P = 0.016), and prior antiplatelet therapy was found to predict better follow-up functional outcome independently (P = 0.032). Among surgically treated intracerebral hemorrhage patients, prior antiplatelet therapy did not increase hematoma volume, rehaemorrhage rate and mortality, and was related to lower follow-up severe morbidity independently." @default.
• W3019861629 created "2020-05-01" @default.
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• W3019861629 date "2020-09-01" @default.
• W3019861629 modified "2023-09-25" @default.
• W3019861629 title "Antiplatelet therapy does not increase mortality of surgical treatment for spontaneous intracerebral haemorrhage" @default.
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• W3019861629 doi "https://doi.org/10.1016/j.clineuro.2020.105873" @default.
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