FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3019934929> ?p ?o ?g. }

• W3019934929 endingPage "241" @default.
• W3019934929 startingPage "235" @default.
• W3019934929 abstract "Synthetic cathinones are new designer drugs that possess hallucinogenic and psychostimulant properties, and are designed to mimic the effects of illegal substances such as cocaine, amphetamines, and 3.4-methylenedioxymethamphetamine (ecstasy) and to produce rewarding effects, circumventing existing laws and penalties. Synthetic cathinones, also referred to as 'bath salts', have become popular particularly among young people since the mid-2000s. Similar to other psychomotor stimulants, synthetic cathinones have the potential to increase monoamine concentration in the synaptic cleft by targeting the plasma membrane transporters of dopamine, norepinephrine, and serotonin. Because of their structural similarities to amphetamines, it has been suggested that synthetic cathinones may have a neurotoxicity profile similar to that of their amphetamine congeners. Therefore, it has been hypothesized that synthetic cathinones may induce neurotoxicity on monoamine nerve endings in the striatum, hippocampus, and cortex. To date, with regard to synthetic cathinone neurotoxicity, parameters such as monoamine depletion, biosynthetic enzyme inhibition, cytotoxicity, generation of reactive oxygen species, pro-oxidation status, and the ability to induce neuroinflammation were investigated in both in vitro and in vivo experimental studies. Compared with amphetamines, synthetic cathinones appear to have more moderate effects than their amphetamine congeners in terms of neurotoxic effects. However, many synthetic cathinone users take these substances simultaneously with other substances such as benzodiazepines, amphetamines, ecstasy, tetrahydrocannabinol, and ethanol and this abuse can modify their neurotoxic effects. Hence, it is important to understand the underlying mechanism of early neurotoxic effects in case of polysubstance use. In this review, we aimed to present up-to-date information on the abuse potential of synthetic cathinones, their legal status, mechanism of action, and particularly their neurotoxic effects." @default.
• W3019934929 created "2020-05-01" @default.
• W3019934929 creator A5000723907 @default.
• W3019934929 creator A5038659591 @default.
• W3019934929 date "2020-04-01" @default.
• W3019934929 modified "2023-09-24" @default.
• W3019934929 title "Psychoactive Bath Salts and Neurotoxicity Risk" @default.
• W3019934929 cites W1546242462 @default.
• W3019934929 cites W1972300539 @default.
• W3019934929 cites W1977213360 @default.
• W3019934929 cites W1981039835 @default.
• W3019934929 cites W1985053470 @default.
• W3019934929 cites W1992897603 @default.
• W3019934929 cites W1995588094 @default.
• W3019934929 cites W2006007311 @default.
• W3019934929 cites W2007084147 @default.
• W3019934929 cites W2014953635 @default.
• W3019934929 cites W2017404713 @default.
• W3019934929 cites W2028940888 @default.
• W3019934929 cites W2062465391 @default.
• W3019934929 cites W2065381999 @default.
• W3019934929 cites W2066033557 @default.
• W3019934929 cites W2072633823 @default.
• W3019934929 cites W2084502769 @default.
• W3019934929 cites W2087971225 @default.
• W3019934929 cites W2094257063 @default.
• W3019934929 cites W2126855384 @default.
• W3019934929 cites W2131622291 @default.
• W3019934929 cites W2145587240 @default.
• W3019934929 cites W2147457603 @default.
• W3019934929 cites W2160588949 @default.
• W3019934929 cites W2163582349 @default.
• W3019934929 cites W2163669209 @default.
• W3019934929 cites W2169359638 @default.
• W3019934929 cites W2215269936 @default.
• W3019934929 cites W2424255509 @default.
• W3019934929 cites W2463600834 @default.
• W3019934929 cites W2529739203 @default.
• W3019934929 cites W2538213990 @default.
• W3019934929 cites W2568924325 @default.
• W3019934929 cites W2685648805 @default.
• W3019934929 cites W2747453246 @default.
• W3019934929 cites W2789907001 @default.
• W3019934929 cites W2790044862 @default.
• W3019934929 cites W2790090607 @default.
• W3019934929 cites W2806523495 @default.
• W3019934929 cites W3005091121 @default.
• W3019934929 doi "https://doi.org/10.4274/tjps.galenos.2018.40820" @default.
• W3019934929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7227911" @default.
• W3019934929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32454785" @default.
• W3019934929 hasPublicationYear "2020" @default.
• W3019934929 type Work @default.
• W3019934929 sameAs 3019934929 @default.
• W3019934929 citedByCount "9" @default.
• W3019934929 countsByYear W30199349292020 @default.
• W3019934929 countsByYear W30199349292021 @default.
• W3019934929 countsByYear W30199349292022 @default.
• W3019934929 countsByYear W30199349292023 @default.
• W3019934929 crossrefType "journal-article" @default.
• W3019934929 hasAuthorship W3019934929A5000723907 @default.
• W3019934929 hasAuthorship W3019934929A5038659591 @default.
• W3019934929 hasBestOaLocation W30199349291 @default.
• W3019934929 hasConcept C118552586 @default.
• W3019934929 hasConcept C15744967 @default.
• W3019934929 hasConcept C169760540 @default.
• W3019934929 hasConcept C170493617 @default.
• W3019934929 hasConcept C178790620 @default.
• W3019934929 hasConcept C185592680 @default.
• W3019934929 hasConcept C187714386 @default.
• W3019934929 hasConcept C2775864247 @default.
• W3019934929 hasConcept C2777193897 @default.
• W3019934929 hasConcept C2777846614 @default.
• W3019934929 hasConcept C2778236026 @default.
• W3019934929 hasConcept C2778961205 @default.
• W3019934929 hasConcept C2779488553 @default.
• W3019934929 hasConcept C2779491297 @default.
• W3019934929 hasConcept C2779972045 @default.
• W3019934929 hasConcept C2780035454 @default.
• W3019934929 hasConcept C2780871563 @default.
• W3019934929 hasConcept C2780876324 @default.
• W3019934929 hasConcept C2781450507 @default.
• W3019934929 hasConcept C29730261 @default.
• W3019934929 hasConcept C513476851 @default.
• W3019934929 hasConcept C55493867 @default.
• W3019934929 hasConcept C71924100 @default.
• W3019934929 hasConcept C98274493 @default.
• W3019934929 hasConceptScore W3019934929C118552586 @default.
• W3019934929 hasConceptScore W3019934929C15744967 @default.
• W3019934929 hasConceptScore W3019934929C169760540 @default.
• W3019934929 hasConceptScore W3019934929C170493617 @default.
• W3019934929 hasConceptScore W3019934929C178790620 @default.
• W3019934929 hasConceptScore W3019934929C185592680 @default.
• W3019934929 hasConceptScore W3019934929C187714386 @default.
• W3019934929 hasConceptScore W3019934929C2775864247 @default.
• W3019934929 hasConceptScore W3019934929C2777193897 @default.
• W3019934929 hasConceptScore W3019934929C2777846614 @default.
• W3019934929 hasConceptScore W3019934929C2778236026 @default.
• W3019934929 hasConceptScore W3019934929C2778961205 @default.

• next