Matches in SemOpenAlex for { <https://semopenalex.org/work/W3020022596> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W3020022596 endingPage "208" @default.
- W3020022596 startingPage "208" @default.
- W3020022596 abstract "The consequence of prolonged treatment with corticosteroids is development of hypertension and metabolic disorders. On the other hand, high levels of sodium chloride in the diet is able to amplify their risks. In a result of that disorders may be development metabolic cardiomyopathy. One of mechanisms that is capable to preventing hypertension and metabolic disorders is nitric oxide system. The research of that system, account short lifetime of the nitric oxide and features its metabolism, can be performed by analysis of nitrite anion (NO 2 - ). It is mainly inactive metabolites in a result of the molecules NO. L-carnitine, as an antioxidant and having the ability to influence to energic metabolism, apoptosis and transcription of DNA may be a promising means for correction disorders in the nitric oxide system. The purpose of our study was to investigate the NO 2 - levels in the animals serum and heart tissue of both sex for long-term action of dexamethasone in conditions of high concentration of 4 % solution sodium chloride in water and use L-carnitine in order to correction data. The experiment was performed with the use of 96 mature white nonlinear rats. It was established that long-term use and high salt content and especially their combination conduced reduce of the NO 2 - level in the serum and ventricular myocardium. The high changes dominanced in the males. L-carnitine demonstrates the ability to recover the metabolite level. The characterised changes occur between both sex in animals with intake of usual quantity sodium chloride in water. The usage water with high content of sodium chloride caused more intensive negative changes but the difference between the sex was not as pronounced. The difference of content NO 2 - in the atria was found only between males and females. The dexamethasone or sodium chloride didn’t exert influence of the NO 2 - metabolism in that tissue." @default.
- W3020022596 created "2020-05-01" @default.
- W3020022596 creator A5031174126 @default.
- W3020022596 date "2020-01-31" @default.
- W3020022596 modified "2023-09-23" @default.
- W3020022596 title "Effects of dexamethasone with sodium chloride load on the nitrite anion content in the rat’s blood serum, heart atria and ventricles" @default.
- W3020022596 doi "https://doi.org/10.12775/jehs.2020.10.01.023" @default.
- W3020022596 hasPublicationYear "2020" @default.
- W3020022596 type Work @default.
- W3020022596 sameAs 3020022596 @default.
- W3020022596 citedByCount "0" @default.
- W3020022596 crossrefType "journal-article" @default.
- W3020022596 hasAuthorship W3020022596A5031174126 @default.
- W3020022596 hasBestOaLocation W30200225961 @default.
- W3020022596 hasConcept C126322002 @default.
- W3020022596 hasConcept C134018914 @default.
- W3020022596 hasConcept C178790620 @default.
- W3020022596 hasConcept C185592680 @default.
- W3020022596 hasConcept C2776179834 @default.
- W3020022596 hasConcept C2776384668 @default.
- W3020022596 hasConcept C2777477808 @default.
- W3020022596 hasConcept C2777633056 @default.
- W3020022596 hasConcept C2778435403 @default.
- W3020022596 hasConcept C2778695967 @default.
- W3020022596 hasConcept C31903555 @default.
- W3020022596 hasConcept C519581460 @default.
- W3020022596 hasConcept C537181965 @default.
- W3020022596 hasConcept C62231903 @default.
- W3020022596 hasConcept C71924100 @default.
- W3020022596 hasConceptScore W3020022596C126322002 @default.
- W3020022596 hasConceptScore W3020022596C134018914 @default.
- W3020022596 hasConceptScore W3020022596C178790620 @default.
- W3020022596 hasConceptScore W3020022596C185592680 @default.
- W3020022596 hasConceptScore W3020022596C2776179834 @default.
- W3020022596 hasConceptScore W3020022596C2776384668 @default.
- W3020022596 hasConceptScore W3020022596C2777477808 @default.
- W3020022596 hasConceptScore W3020022596C2777633056 @default.
- W3020022596 hasConceptScore W3020022596C2778435403 @default.
- W3020022596 hasConceptScore W3020022596C2778695967 @default.
- W3020022596 hasConceptScore W3020022596C31903555 @default.
- W3020022596 hasConceptScore W3020022596C519581460 @default.
- W3020022596 hasConceptScore W3020022596C537181965 @default.
- W3020022596 hasConceptScore W3020022596C62231903 @default.
- W3020022596 hasConceptScore W3020022596C71924100 @default.
- W3020022596 hasIssue "1" @default.
- W3020022596 hasLocation W30200225961 @default.
- W3020022596 hasLocation W30200225962 @default.
- W3020022596 hasOpenAccess W3020022596 @default.
- W3020022596 hasPrimaryLocation W30200225961 @default.
- W3020022596 hasRelatedWork W303335 @default.
- W3020022596 hasRelatedWork W3151840 @default.
- W3020022596 hasRelatedWork W3722347 @default.
- W3020022596 hasRelatedWork W5192271 @default.
- W3020022596 hasRelatedWork W6594882 @default.
- W3020022596 hasRelatedWork W7120801 @default.
- W3020022596 hasRelatedWork W7933501 @default.
- W3020022596 hasRelatedWork W807710 @default.
- W3020022596 hasRelatedWork W8566587 @default.
- W3020022596 hasRelatedWork W9104097 @default.
- W3020022596 hasVolume "10" @default.
- W3020022596 isParatext "false" @default.
- W3020022596 isRetracted "false" @default.
- W3020022596 magId "3020022596" @default.
- W3020022596 workType "article" @default.