Matches in SemOpenAlex for { <https://semopenalex.org/work/W3020121229> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W3020121229 endingPage "117s" @default.
- W3020121229 startingPage "117s" @default.
- W3020121229 abstract "INTRODUCTION: Cell free DNA (cfDNA) is the recommended screening test for aneuploidy in women age 35 and over. We conducted a systematic review of factors associated with a failed cfDNA result following routine aneuploidy screening. METHODS: PubMed, Scopus, Clinicaltrials.gov and Cochrane were searched for articles from inception to October 2018. Patients undergoing routine cfDNA aneuploidy screening at ≥ 10 weeks gestational age and who had a viable pregnancy were included. Cohort studies and randomized controlled trials were included. Case reports and case series with less than five patients were excluded. The outcome was test failure. RESULTS: Our search yielded 756 results. 19 studies met our inclusion criteria and included 506,709 patients. Aneuploidy, maternal obesity, Low-Molecular Weight Heparin (LMWH), and IVF were associated with increased rates of test failure. 12 articles reported aneuploidy as an associated factor in inconclusive results, specifically triploidy and trisomies 13, 18, and 21. One study reported trisomy 9 in a result failure. In six studies, obesity was associated with higher failure rates. Failure rates in obese women was reported at 51.5% compared to 0.7% in non-obese women in one study. Two studies reported increased failure rates in women with LMWH. 75% of women who received failed results were on LMWH in one study. One study reported a 3% higher test failure rate in women who underwent in-vitro fertilization. CONCLUSION: Fetal aneuploidy, maternal obesity, LMWH, and IVF are associated with increased rates of failure in cfDNA following routine aneuploidy screening." @default.
- W3020121229 created "2020-05-01" @default.
- W3020121229 creator A5050654890 @default.
- W3020121229 creator A5051213422 @default.
- W3020121229 creator A5071292401 @default.
- W3020121229 date "2020-05-01" @default.
- W3020121229 modified "2023-09-27" @default.
- W3020121229 title "Factors Associated With Failed Routine Aneuploidy Cell-Free DNA Screening" @default.
- W3020121229 doi "https://doi.org/10.1097/01.aog.0000664452.04659.34" @default.
- W3020121229 hasPublicationYear "2020" @default.
- W3020121229 type Work @default.
- W3020121229 sameAs 3020121229 @default.
- W3020121229 citedByCount "0" @default.
- W3020121229 crossrefType "journal-article" @default.
- W3020121229 hasAuthorship W3020121229A5050654890 @default.
- W3020121229 hasAuthorship W3020121229A5051213422 @default.
- W3020121229 hasAuthorship W3020121229A5071292401 @default.
- W3020121229 hasConcept C104317684 @default.
- W3020121229 hasConcept C126322002 @default.
- W3020121229 hasConcept C131872663 @default.
- W3020121229 hasConcept C2776229224 @default.
- W3020121229 hasConcept C2779672484 @default.
- W3020121229 hasConcept C29456083 @default.
- W3020121229 hasConcept C30481170 @default.
- W3020121229 hasConcept C54355233 @default.
- W3020121229 hasConcept C71924100 @default.
- W3020121229 hasConcept C86803240 @default.
- W3020121229 hasConceptScore W3020121229C104317684 @default.
- W3020121229 hasConceptScore W3020121229C126322002 @default.
- W3020121229 hasConceptScore W3020121229C131872663 @default.
- W3020121229 hasConceptScore W3020121229C2776229224 @default.
- W3020121229 hasConceptScore W3020121229C2779672484 @default.
- W3020121229 hasConceptScore W3020121229C29456083 @default.
- W3020121229 hasConceptScore W3020121229C30481170 @default.
- W3020121229 hasConceptScore W3020121229C54355233 @default.
- W3020121229 hasConceptScore W3020121229C71924100 @default.
- W3020121229 hasConceptScore W3020121229C86803240 @default.
- W3020121229 hasIssue "1" @default.
- W3020121229 hasLocation W30201212291 @default.
- W3020121229 hasOpenAccess W3020121229 @default.
- W3020121229 hasPrimaryLocation W30201212291 @default.
- W3020121229 hasRelatedWork W1972246389 @default.
- W3020121229 hasRelatedWork W2051300822 @default.
- W3020121229 hasRelatedWork W2068724449 @default.
- W3020121229 hasRelatedWork W2136826099 @default.
- W3020121229 hasRelatedWork W2163887834 @default.
- W3020121229 hasRelatedWork W2897782607 @default.
- W3020121229 hasRelatedWork W2905997830 @default.
- W3020121229 hasRelatedWork W4238396316 @default.
- W3020121229 hasRelatedWork W4253439116 @default.
- W3020121229 hasRelatedWork W2334477804 @default.
- W3020121229 hasVolume "135" @default.
- W3020121229 isParatext "false" @default.
- W3020121229 isRetracted "false" @default.
- W3020121229 magId "3020121229" @default.
- W3020121229 workType "article" @default.