FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3020194879> ?p ?o ?g. }

• W3020194879 abstract "Abstract The initiation of protein synthesis in bacteria is ruled by three canonical factors: IF1, IF2, and IF3. This system persists in human mitochondria; however, it functions in a rather different way due to specialization and adaptation to the organellar micro-environment. We focused on human mitochondrial IF3, which was earlier studied in vitro , but no knock-out cellular models have been published up to date. In this work, we generated human HeLa cell lines deficient in the MTIF3 gene and analyzed their mitochondrial function. Despite the lack of IF3mt in these cells, they preserved functional mitochondria capable of oxygen consumption and protein synthesis; however, the translation of ATP6 mRNA was selectively decreased which compromised the assembly of ATP synthase. Together with the analogous results obtained earlier for baker’s yeast mitochondrial IF3, our findings point to a functional divergence of mitochondrial initiation factors from their bacterial ancestors." @default.
• W3020194879 created "2020-05-01" @default.
• W3020194879 creator A5020360506 @default.
• W3020194879 creator A5024341171 @default.
• W3020194879 creator A5030666535 @default.
• W3020194879 creator A5046250033 @default.
• W3020194879 creator A5074590072 @default.
• W3020194879 creator A5086701246 @default.
• W3020194879 date "2020-04-28" @default.
• W3020194879 modified "2023-09-23" @default.
• W3020194879 title "Initiation Factor 3 is Dispensable For Mitochondrial Translation in Cultured Human Cells" @default.
• W3020194879 cites W1480388053 @default.
• W3020194879 cites W1556836946 @default.
• W3020194879 cites W1954517756 @default.
• W3020194879 cites W1963535936 @default.
• W3020194879 cites W1986908018 @default.
• W3020194879 cites W2001845502 @default.
• W3020194879 cites W2020293695 @default.
• W3020194879 cites W2026186743 @default.
• W3020194879 cites W2057914919 @default.
• W3020194879 cites W2064815984 @default.
• W3020194879 cites W2068119233 @default.
• W3020194879 cites W2099540110 @default.
• W3020194879 cites W2101108802 @default.
• W3020194879 cites W2104990377 @default.
• W3020194879 cites W2149357806 @default.
• W3020194879 cites W2153851191 @default.
• W3020194879 cites W2189856487 @default.
• W3020194879 cites W2411573209 @default.
• W3020194879 cites W2532753205 @default.
• W3020194879 cites W2552202209 @default.
• W3020194879 cites W2624338235 @default.
• W3020194879 cites W2767078779 @default.
• W3020194879 cites W2767739777 @default.
• W3020194879 cites W2902478583 @default.
• W3020194879 cites W2906731985 @default.
• W3020194879 cites W2953919337 @default.
• W3020194879 cites W2995565258 @default.
• W3020194879 doi "https://doi.org/10.1038/s41598-020-64139-5" @default.
• W3020194879 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7188818" @default.
• W3020194879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32346061" @default.
• W3020194879 hasPublicationYear "2020" @default.
• W3020194879 type Work @default.
• W3020194879 sameAs 3020194879 @default.
• W3020194879 citedByCount "12" @default.
• W3020194879 countsByYear W30201948792020 @default.
• W3020194879 countsByYear W30201948792021 @default.
• W3020194879 countsByYear W30201948792022 @default.
• W3020194879 countsByYear W30201948792023 @default.
• W3020194879 crossrefType "journal-article" @default.
• W3020194879 hasAuthorship W3020194879A5020360506 @default.
• W3020194879 hasAuthorship W3020194879A5024341171 @default.
• W3020194879 hasAuthorship W3020194879A5030666535 @default.
• W3020194879 hasAuthorship W3020194879A5046250033 @default.
• W3020194879 hasAuthorship W3020194879A5074590072 @default.
• W3020194879 hasAuthorship W3020194879A5086701246 @default.
• W3020194879 hasBestOaLocation W30201948791 @default.
• W3020194879 hasConcept C104317684 @default.
• W3020194879 hasConcept C105580179 @default.
• W3020194879 hasConcept C142587794 @default.
• W3020194879 hasConcept C149364088 @default.
• W3020194879 hasConcept C163950672 @default.
• W3020194879 hasConcept C24586158 @default.
• W3020194879 hasConcept C2777614518 @default.
• W3020194879 hasConcept C28859421 @default.
• W3020194879 hasConcept C3675279 @default.
• W3020194879 hasConcept C4718897 @default.
• W3020194879 hasConcept C54355233 @default.
• W3020194879 hasConcept C62493599 @default.
• W3020194879 hasConcept C86803240 @default.
• W3020194879 hasConcept C95444343 @default.
• W3020194879 hasConceptScore W3020194879C104317684 @default.
• W3020194879 hasConceptScore W3020194879C105580179 @default.
• W3020194879 hasConceptScore W3020194879C142587794 @default.
• W3020194879 hasConceptScore W3020194879C149364088 @default.
• W3020194879 hasConceptScore W3020194879C163950672 @default.
• W3020194879 hasConceptScore W3020194879C24586158 @default.
• W3020194879 hasConceptScore W3020194879C2777614518 @default.
• W3020194879 hasConceptScore W3020194879C28859421 @default.
• W3020194879 hasConceptScore W3020194879C3675279 @default.
• W3020194879 hasConceptScore W3020194879C4718897 @default.
• W3020194879 hasConceptScore W3020194879C54355233 @default.
• W3020194879 hasConceptScore W3020194879C62493599 @default.
• W3020194879 hasConceptScore W3020194879C86803240 @default.
• W3020194879 hasConceptScore W3020194879C95444343 @default.
• W3020194879 hasIssue "1" @default.
• W3020194879 hasLocation W30201948791 @default.
• W3020194879 hasLocation W30201948792 @default.
• W3020194879 hasLocation W30201948793 @default.
• W3020194879 hasOpenAccess W3020194879 @default.
• W3020194879 hasPrimaryLocation W30201948791 @default.
• W3020194879 hasRelatedWork W1502026043 @default.
• W3020194879 hasRelatedWork W2020985206 @default.
• W3020194879 hasRelatedWork W2097769256 @default.
• W3020194879 hasRelatedWork W2161624752 @default.
• W3020194879 hasRelatedWork W2317519480 @default.
• W3020194879 hasRelatedWork W2376017112 @default.
• W3020194879 hasRelatedWork W2981098037 @default.
• W3020194879 hasRelatedWork W4200431467 @default.
• W3020194879 hasRelatedWork W4210805057 @default.

• next