FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3020204001> ?p ?o ?g. }

• W3020204001 abstract "Background:Candida is a normal commensal of the oral cavity; these microorganisms can be isolated in 20% to 80% of healthy individuals. Oral candidiasis (OC) is the most common fungal infection related to the oral cavity caused by the most common opportunistic fungus (C. albicans). The management of oral candidiasis involves removal or reduction of predisposing factors together with the administration of an antimitotic agent either in topical or systemic form with or without chlorhexidine (CHX). The increasing number of people who are immunosuppressed and the development of antimicrobial resistance, has necessitated there is a need to explore others treatment to fight this infectious disease. This led to the exploration and use of beneficial microorganisms (probiotics) as an alternative prophylactic & therapeutic mode of treatment against Candida infections.Aim:To evaluate the effect of percentage combination of chlorhexidine (CHX) and probiotics on (PB) C. albicans growth.Method:The study was conducted in the Department of Oral Medicine and Periodontology and the Oral and Dental Research Laboratory (ODRL) at the Faculty of Dentistry, University of the Western Cape, Tygerberg campus. This in-vitro laboratory study was based on the established principle of spread plate technique followed by colony counting on selective media and non-selective media. Chlorhexidine (CHX) and probiotics (PB) were combined at different concentrations (XCHXyPB) (percentage combination), the added sum of which equals to 100 % (the percentage is achieved by multiplication of volumes (V*V)), to evaluate their effect on C. albicans. The treatments were incubated at 37°C for 30 minutes and 24 hours. Serial dilution was carried out on a micro-titer plate based on McFarland standards. A fixed volume (100 μL)of the solution was transferred into plates (selective and non-selective media). Deionized water served as a control (negative).Results:100 μL CHX with 0 μL PB (100 CHX 0 PB) had a mean value of (0) at both 30 minutes and 24 hours. While 25 μL CHX with 75 μL PB (25 CHX 75 PB) the mean value (9.4) at 30 minutes and (9.5) at 24 hours. 0 μL CHX with 100 μL PB (0 CHX 100 PB) the mean value was (9.6) at 30 minutes while at 24 hours the mean value was (9.9). The control (0 CHX 0 PB) showed at 30 minutes and at 24 hours slightly similar reading (mean) as for the 0 μL CHX with 100 μL PB (0 CHX 100 PB). The largest difference was between the control (0 μL CHX with 0 μL PB) (0 CHX 0 PB) versus 100 μL of CHX with 0 μL PB (100 CHX 0 PB) (9.692), p <0.001. The smallest difference was between control (0 μL CHX with 0 μL PB) (0 CHX 0 PB) versus 0 μL CHX with 100 μL PB (0 CHX 100 PB).Conclusion:Chlorhexidine (CHX) and probiotics (PB) could be used at different combination concentration, provided that the CHX ratio is lower than the PB. Depending on the combination used, the number of colonies were slightly different. CHX (100 CHX) showed the lowest number of colonies (zero), while probiotics (0 CHX 100 PB) showed the highest number of…" @default.
• W3020204001 created "2020-05-01" @default.
• W3020204001 creator A5079004442 @default.
• W3020204001 date "2019-01-01" @default.
• W3020204001 modified "2023-09-27" @default.
• W3020204001 title "The effect of percentage combination of probiotics and chlorhexidine on C. albicans" @default.
• W3020204001 hasPublicationYear "2019" @default.
• W3020204001 type Work @default.
• W3020204001 sameAs 3020204001 @default.
• W3020204001 citedByCount "0" @default.
• W3020204001 crossrefType "journal-article" @default.
• W3020204001 hasAuthorship W3020204001A5079004442 @default.
• W3020204001 hasConcept C145081991 @default.
• W3020204001 hasConcept C158689903 @default.
• W3020204001 hasConcept C199343813 @default.
• W3020204001 hasConcept C2777084678 @default.
• W3020204001 hasConcept C2780917455 @default.
• W3020204001 hasConcept C2986629439 @default.
• W3020204001 hasConcept C4937899 @default.
• W3020204001 hasConcept C523546767 @default.
• W3020204001 hasConcept C54355233 @default.
• W3020204001 hasConcept C71924100 @default.
• W3020204001 hasConcept C86803240 @default.
• W3020204001 hasConcept C89423630 @default.
• W3020204001 hasConceptScore W3020204001C145081991 @default.
• W3020204001 hasConceptScore W3020204001C158689903 @default.
• W3020204001 hasConceptScore W3020204001C199343813 @default.
• W3020204001 hasConceptScore W3020204001C2777084678 @default.
• W3020204001 hasConceptScore W3020204001C2780917455 @default.
• W3020204001 hasConceptScore W3020204001C2986629439 @default.
• W3020204001 hasConceptScore W3020204001C4937899 @default.
• W3020204001 hasConceptScore W3020204001C523546767 @default.
• W3020204001 hasConceptScore W3020204001C54355233 @default.
• W3020204001 hasConceptScore W3020204001C71924100 @default.
• W3020204001 hasConceptScore W3020204001C86803240 @default.
• W3020204001 hasConceptScore W3020204001C89423630 @default.
• W3020204001 hasLocation W30202040011 @default.
• W3020204001 hasOpenAccess W3020204001 @default.
• W3020204001 hasPrimaryLocation W30202040011 @default.
• W3020204001 hasRelatedWork W1484354215 @default.
• W3020204001 hasRelatedWork W1820721978 @default.
• W3020204001 hasRelatedWork W1974479066 @default.
• W3020204001 hasRelatedWork W1992172804 @default.
• W3020204001 hasRelatedWork W2036398044 @default.
• W3020204001 hasRelatedWork W2055771137 @default.
• W3020204001 hasRelatedWork W2058241112 @default.
• W3020204001 hasRelatedWork W2059769954 @default.
• W3020204001 hasRelatedWork W2062239202 @default.
• W3020204001 hasRelatedWork W2096108287 @default.
• W3020204001 hasRelatedWork W2116367188 @default.
• W3020204001 hasRelatedWork W2152172270 @default.
• W3020204001 hasRelatedWork W2164081605 @default.
• W3020204001 hasRelatedWork W2566772624 @default.
• W3020204001 hasRelatedWork W2599904180 @default.
• W3020204001 hasRelatedWork W2622833782 @default.
• W3020204001 hasRelatedWork W2769095687 @default.
• W3020204001 hasRelatedWork W2778185083 @default.
• W3020204001 hasRelatedWork W2900430317 @default.
• W3020204001 hasRelatedWork W3175981265 @default.
• W3020204001 isParatext "false" @default.
• W3020204001 isRetracted "false" @default.
• W3020204001 magId "3020204001" @default.
• W3020204001 workType "article" @default.