Matches in SemOpenAlex for { <https://semopenalex.org/work/W3020280166> ?p ?o ?g. }
- W3020280166 endingPage "611" @default.
- W3020280166 startingPage "611" @default.
- W3020280166 abstract "Tripeptide glutathione, which plays important roles in many cellular mechanisms, is also a biotechnology-oriented molecule with applications in medicine, food and cosmetic. Here, the engineering of the yeast Yarrowia lipolytica for the production of this metabolite at high titer values from various agro-industrial by-products is reported. The constitutive overexpression of the glutathione biosynthetic genes GSH1 and GSH2 encoding respectively γ-glutamylcysteine synthetase and glutathione synthetase, together with the INU1 gene from Kluyveromyces marxianus encoding inulinase yielded a glutathione titer value and a productivity of 644 nmol/mg protein and 510 µmol/gDCW, respectively. These values were obtained during bioreactor batch cultures in a medium exclusively comprising an extract of Jerusalem artichoke tuber, used as a source of inulin, and ammonium sulfate, used as a nitrogen source." @default.
- W3020280166 created "2020-05-01" @default.
- W3020280166 creator A5005131197 @default.
- W3020280166 creator A5018669500 @default.
- W3020280166 date "2020-04-23" @default.
- W3020280166 modified "2023-10-16" @default.
- W3020280166 title "Engineering Yarrowia lipolytica for the Synthesis of Glutathione from Organic By-Products" @default.
- W3020280166 cites W1414630228 @default.
- W3020280166 cites W1940961262 @default.
- W3020280166 cites W1983972257 @default.
- W3020280166 cites W1991349267 @default.
- W3020280166 cites W2000235097 @default.
- W3020280166 cites W2005025492 @default.
- W3020280166 cites W2026352030 @default.
- W3020280166 cites W2030794248 @default.
- W3020280166 cites W2030965451 @default.
- W3020280166 cites W2037447742 @default.
- W3020280166 cites W2049965804 @default.
- W3020280166 cites W2051465130 @default.
- W3020280166 cites W2074732464 @default.
- W3020280166 cites W2093245102 @default.
- W3020280166 cites W2107277218 @default.
- W3020280166 cites W2114927367 @default.
- W3020280166 cites W2124743526 @default.
- W3020280166 cites W2128635872 @default.
- W3020280166 cites W2158904737 @default.
- W3020280166 cites W2161138858 @default.
- W3020280166 cites W217847191 @default.
- W3020280166 cites W2192080449 @default.
- W3020280166 cites W2340174019 @default.
- W3020280166 cites W2404001189 @default.
- W3020280166 cites W2494406106 @default.
- W3020280166 cites W2527837945 @default.
- W3020280166 cites W2596763875 @default.
- W3020280166 cites W2598445731 @default.
- W3020280166 cites W2611457812 @default.
- W3020280166 cites W2619940870 @default.
- W3020280166 cites W2626998764 @default.
- W3020280166 cites W2731790145 @default.
- W3020280166 cites W2747790759 @default.
- W3020280166 cites W2773395695 @default.
- W3020280166 cites W2793359412 @default.
- W3020280166 cites W2796101530 @default.
- W3020280166 cites W2799374850 @default.
- W3020280166 cites W2901211904 @default.
- W3020280166 cites W2942835310 @default.
- W3020280166 cites W2965514452 @default.
- W3020280166 cites W2975308748 @default.
- W3020280166 cites W4230378852 @default.
- W3020280166 cites W4293247451 @default.
- W3020280166 doi "https://doi.org/10.3390/microorganisms8040611" @default.
- W3020280166 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7232331" @default.
- W3020280166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32340345" @default.
- W3020280166 hasPublicationYear "2020" @default.
- W3020280166 type Work @default.
- W3020280166 sameAs 3020280166 @default.
- W3020280166 citedByCount "3" @default.
- W3020280166 countsByYear W30202801662020 @default.
- W3020280166 countsByYear W30202801662021 @default.
- W3020280166 countsByYear W30202801662023 @default.
- W3020280166 crossrefType "journal-article" @default.
- W3020280166 hasAuthorship W3020280166A5005131197 @default.
- W3020280166 hasAuthorship W3020280166A5018669500 @default.
- W3020280166 hasBestOaLocation W30202801661 @default.
- W3020280166 hasConcept C100544194 @default.
- W3020280166 hasConcept C145890019 @default.
- W3020280166 hasConcept C167392928 @default.
- W3020280166 hasConcept C168170006 @default.
- W3020280166 hasConcept C181199279 @default.
- W3020280166 hasConcept C185592680 @default.
- W3020280166 hasConcept C2775884923 @default.
- W3020280166 hasConcept C2779222958 @default.
- W3020280166 hasConcept C2779344277 @default.
- W3020280166 hasConcept C2779490540 @default.
- W3020280166 hasConcept C31903555 @default.
- W3020280166 hasConcept C515207424 @default.
- W3020280166 hasConcept C538909803 @default.
- W3020280166 hasConcept C55493867 @default.
- W3020280166 hasConcept C59822182 @default.
- W3020280166 hasConcept C86803240 @default.
- W3020280166 hasConceptScore W3020280166C100544194 @default.
- W3020280166 hasConceptScore W3020280166C145890019 @default.
- W3020280166 hasConceptScore W3020280166C167392928 @default.
- W3020280166 hasConceptScore W3020280166C168170006 @default.
- W3020280166 hasConceptScore W3020280166C181199279 @default.
- W3020280166 hasConceptScore W3020280166C185592680 @default.
- W3020280166 hasConceptScore W3020280166C2775884923 @default.
- W3020280166 hasConceptScore W3020280166C2779222958 @default.
- W3020280166 hasConceptScore W3020280166C2779344277 @default.
- W3020280166 hasConceptScore W3020280166C2779490540 @default.
- W3020280166 hasConceptScore W3020280166C31903555 @default.
- W3020280166 hasConceptScore W3020280166C515207424 @default.
- W3020280166 hasConceptScore W3020280166C538909803 @default.
- W3020280166 hasConceptScore W3020280166C55493867 @default.
- W3020280166 hasConceptScore W3020280166C59822182 @default.
- W3020280166 hasConceptScore W3020280166C86803240 @default.
- W3020280166 hasIssue "4" @default.
- W3020280166 hasLocation W30202801661 @default.