Matches in SemOpenAlex for { <https://semopenalex.org/work/W3020777790> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3020777790 abstract "ABSTRACT The SARS-CoV-2 pandemic has caused a severe, international shortage of N95 respirators, which are essential to protect healthcare providers from infection. Given the contemporary limitations of the supply chain, it is imperative to identify effective means of decontaminating, reusing, and thereby conserving N95 respirator stockpiles. To be effective, decontamination must result in sterilization of the N95 respirator without impairment of respirator filtration or user fit. Although numerous methods of N95 decontamination exist, none are universally accessible. In this work we describe a microwave-generated steam decontamination protocol for N95 respirators for use in healthcare systems of all sizes, geographies, and means. Using widely available glass containers, mesh from commercial produce bags, a rubber band, and a 1100W commercially available microwave, we constructed an effective, standardized, and reproducible means of decontaminating N95 respirators. Employing this methodology against MS2 phage, a highly conservative surrogate for SARS-CoV-2 contamination, we report an average 6-log 10 plaque forming unit (PFU) (99.9999%) and a minimum 5-log 10 PFU (99.999%) reduction after a single three-minute microwave treatment. Notably, quantified respirator fit and function were preserved, even after 20 sequential cycles of microwave steam decontamination. This method provides a valuable means of effective decontamination and reuse of N95 respirators by frontline providers facing urgent need. IMPORTANCE Due to the rapid spread of COVID-19 there is an increasing shortage of protective gear necessary to keep health care providers safe from infection. The CDC reports 9,282 cases of COVID-19 among U.S. healthcare workers to date (1). N95 respirators are recommended by the CDC as the ideal method of protection from COVID-19. Although N95 respirators are traditionally single-use, the shortages have necessitated the need for re-use. Effective methods of N95 decontamination that do not affect the fit or filtration ability of N95 respirators are essential. Numerous methods of N95 decontamination exist; however, none are universally accessible. In this study we describe an effective, standardized, and reproducible means of decontaminating N95 respirators using widely available materials. The N95 decontamination method described in this work will provide a valuable resource for hospitals, healthcare centers, and outpatients practices that are experiencing increasing shortages of N95 respirators due to the COVID-19 pandemic." @default.
- W3020777790 created "2020-05-01" @default.
- W3020777790 creator A5016519747 @default.
- W3020777790 creator A5016768442 @default.
- W3020777790 creator A5029190172 @default.
- W3020777790 creator A5047957924 @default.
- W3020777790 creator A5064959859 @default.
- W3020777790 creator A5066514578 @default.
- W3020777790 creator A5079913640 @default.
- W3020777790 creator A5084254954 @default.
- W3020777790 date "2020-04-25" @default.
- W3020777790 modified "2023-09-26" @default.
- W3020777790 title "Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials" @default.
- W3020777790 cites W1968431971 @default.
- W3020777790 cites W2022925341 @default.
- W3020777790 cites W2082462695 @default.
- W3020777790 cites W2168060225 @default.
- W3020777790 cites W2171977798 @default.
- W3020777790 cites W2586332156 @default.
- W3020777790 cites W2598389566 @default.
- W3020777790 cites W2966752388 @default.
- W3020777790 cites W3008443627 @default.
- W3020777790 cites W3008452791 @default.
- W3020777790 cites W3012099172 @default.
- W3020777790 doi "https://doi.org/10.1101/2020.04.22.20076117" @default.
- W3020777790 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7276004" @default.
- W3020777790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32511577" @default.
- W3020777790 hasPublicationYear "2020" @default.
- W3020777790 type Work @default.
- W3020777790 sameAs 3020777790 @default.
- W3020777790 citedByCount "4" @default.
- W3020777790 countsByYear W30207777902020 @default.
- W3020777790 countsByYear W30207777902021 @default.
- W3020777790 crossrefType "posted-content" @default.
- W3020777790 hasAuthorship W3020777790A5016519747 @default.
- W3020777790 hasAuthorship W3020777790A5016768442 @default.
- W3020777790 hasAuthorship W3020777790A5029190172 @default.
- W3020777790 hasAuthorship W3020777790A5047957924 @default.
- W3020777790 hasAuthorship W3020777790A5064959859 @default.
- W3020777790 hasAuthorship W3020777790A5066514578 @default.
- W3020777790 hasAuthorship W3020777790A5079913640 @default.
- W3020777790 hasAuthorship W3020777790A5084254954 @default.
- W3020777790 hasBestOaLocation W30207777901 @default.
- W3020777790 hasConcept C107211472 @default.
- W3020777790 hasConcept C127413603 @default.
- W3020777790 hasConcept C138885662 @default.
- W3020777790 hasConcept C142724271 @default.
- W3020777790 hasConcept C158816027 @default.
- W3020777790 hasConcept C159985019 @default.
- W3020777790 hasConcept C192562407 @default.
- W3020777790 hasConcept C194051981 @default.
- W3020777790 hasConcept C206588197 @default.
- W3020777790 hasConcept C2778137410 @default.
- W3020777790 hasConcept C2779134260 @default.
- W3020777790 hasConcept C3008058167 @default.
- W3020777790 hasConcept C39432304 @default.
- W3020777790 hasConcept C41895202 @default.
- W3020777790 hasConcept C524204448 @default.
- W3020777790 hasConcept C548081761 @default.
- W3020777790 hasConcept C71924100 @default.
- W3020777790 hasConceptScore W3020777790C107211472 @default.
- W3020777790 hasConceptScore W3020777790C127413603 @default.
- W3020777790 hasConceptScore W3020777790C138885662 @default.
- W3020777790 hasConceptScore W3020777790C142724271 @default.
- W3020777790 hasConceptScore W3020777790C158816027 @default.
- W3020777790 hasConceptScore W3020777790C159985019 @default.
- W3020777790 hasConceptScore W3020777790C192562407 @default.
- W3020777790 hasConceptScore W3020777790C194051981 @default.
- W3020777790 hasConceptScore W3020777790C206588197 @default.
- W3020777790 hasConceptScore W3020777790C2778137410 @default.
- W3020777790 hasConceptScore W3020777790C2779134260 @default.
- W3020777790 hasConceptScore W3020777790C3008058167 @default.
- W3020777790 hasConceptScore W3020777790C39432304 @default.
- W3020777790 hasConceptScore W3020777790C41895202 @default.
- W3020777790 hasConceptScore W3020777790C524204448 @default.
- W3020777790 hasConceptScore W3020777790C548081761 @default.
- W3020777790 hasConceptScore W3020777790C71924100 @default.
- W3020777790 hasLocation W30207777901 @default.
- W3020777790 hasLocation W30207777902 @default.
- W3020777790 hasLocation W30207777903 @default.
- W3020777790 hasOpenAccess W3020777790 @default.
- W3020777790 hasPrimaryLocation W30207777901 @default.
- W3020777790 hasRelatedWork W11559005 @default.
- W3020777790 hasRelatedWork W13410377 @default.
- W3020777790 hasRelatedWork W13509517 @default.
- W3020777790 hasRelatedWork W26702481 @default.
- W3020777790 hasRelatedWork W29166168 @default.
- W3020777790 hasRelatedWork W31648734 @default.
- W3020777790 hasRelatedWork W35681962 @default.
- W3020777790 hasRelatedWork W37309852 @default.
- W3020777790 hasRelatedWork W42676684 @default.
- W3020777790 hasRelatedWork W48543888 @default.
- W3020777790 isParatext "false" @default.
- W3020777790 isRetracted "false" @default.
- W3020777790 magId "3020777790" @default.
- W3020777790 workType "article" @default.