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- W3021044987 abstract "The relationship between cerebral white–matter lesions and cognitive performance has been one of the most controversial issues. Some research showed poorer neuropsychological performance in AD patients with severe WML than in those with mild WML. However, others showed no major differences on a broad neuropsychological battery. This study is aimed to evaluate any relationship between cerebral white–matter lesions and Camcog, which is one of the neuropsychological tests, in probable Alzheimer's disease of NINCDS–ADRDA. Subjects included 60 (men 17, women 43) patients. All subjects received brain magnetic resonance scanning (B–MRI) and Camcog, which is a cognitive test part of CAMDEX and is divided into 7 cognitive subsets, such as orientation, language, memory, attention/calculation, praxis, abstract thinking, and perception. White matter changes in B–MRI were rated with Manolio scale, ranged from 0 to 9. AD patients with more severe WML have proorer neurocognitive function, especially orientation, language, atttention, praxis, and perception, and the severity of WML is correlated with orientation, language, praxis, perception, and total score of Camcog. We did not compare to patients without white matter change. However, we found that the severity of cerebral white matter lesions are associated with impairment of orientation, language function, praxis, and perception." @default.
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- W3021044987 date "2006-07-01" @default.
- W3021044987 modified "2023-09-27" @default.
- W3021044987 title "P2-332: Neuropsychological test in Alzheimer's disease with white matter lesion" @default.
- W3021044987 doi "https://doi.org/10.1016/j.jalz.2006.05.1172" @default.
- W3021044987 hasPublicationYear "2006" @default.
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