FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021136082> ?p ?o ?g. }

• W3021136082 endingPage "112953" @default.
• W3021136082 startingPage "112953" @default.
• W3021136082 abstract "Danggui Buxue Tang (DBT) has been used to promote hematopoiesis and relieve myelosuppression in China. Antibiotics can cause myelosuppression through gut microbiota disorders. Aim of the study: This study aims to explore the way of DBT to alleviate the metabolic disorder caused by antibiotics. In this study, 16S rRNA sequencing was used to detect the change of gut microbiota, metabolomics to analyze the change of metabolites. Correlation analysis was used to establishment the correlation between gut microbiota and metabolites. PICRUST 2 was used to predict the function of gut microbiota. Results showed that eighty-two genera of gut microbiota were affected by antibiotic, while twelve were significantly restored after DBT. Seventy-four potential metabolites were significantly different from the antibiotics and DBT. We found significant recovery by the Bacteroides and Rikenellaceae RC9 after DBT. The metabolic pathways influenced by the antibiotic treatment included primary and secondary bile biosynthesis, etc. The metabolic pathways that could be restored after DBT included the primary and secondary bile acid biosynthesis pathway, etc. Through correlation analysis, we found a correlation between the Bacteroides, Rikenellaceae_RC9_gut_group and other potential differential metabolisms such as those of taurodeoxycholic acid, N-phenylacetyl glycine, etc. The functional prediction showed that the biosynthesis of primary bile acid, secondary bile acid was significantly affected. DBT can restore the gut and reverse the metabolic disorder caused by antibiotics through Bacteroides, and it provides a new medical idea regarding the gut microbiota balance." @default.
• W3021136082 created "2020-05-13" @default.
• W3021136082 creator A5007931200 @default.
• W3021136082 creator A5010599695 @default.
• W3021136082 creator A5042339155 @default.
• W3021136082 creator A5059484326 @default.
• W3021136082 creator A5065927898 @default.
• W3021136082 creator A5076846612 @default.
• W3021136082 creator A5080000178 @default.
• W3021136082 creator A5082857859 @default.
• W3021136082 date "2020-09-01" @default.
• W3021136082 modified "2023-10-15" @default.
• W3021136082 title "Danggui Buxue Tang restores antibiotic-induced metabolic disorders by remodeling the gut microbiota" @default.
• W3021136082 cites W1971240883 @default.
• W3021136082 cites W2019087671 @default.
• W3021136082 cites W2028047221 @default.
• W3021136082 cites W2066382988 @default.
• W3021136082 cites W2071534982 @default.
• W3021136082 cites W2093929553 @default.
• W3021136082 cites W2107869090 @default.
• W3021136082 cites W2108281900 @default.
• W3021136082 cites W2110300022 @default.
• W3021136082 cites W2152714616 @default.
• W3021136082 cites W2408795218 @default.
• W3021136082 cites W2586161535 @default.
• W3021136082 cites W2589364187 @default.
• W3021136082 cites W2607034313 @default.
• W3021136082 cites W2735190149 @default.
• W3021136082 cites W2761145411 @default.
• W3021136082 cites W2774287749 @default.
• W3021136082 cites W2789762860 @default.
• W3021136082 cites W2901911228 @default.
• W3021136082 cites W2912119023 @default.
• W3021136082 cites W2912270772 @default.
• W3021136082 cites W2914831820 @default.
• W3021136082 cites W2915379541 @default.
• W3021136082 cites W2937567065 @default.
• W3021136082 cites W2950703836 @default.
• W3021136082 cites W2970210695 @default.
• W3021136082 cites W2972007077 @default.
• W3021136082 cites W958079127 @default.
• W3021136082 doi "https://doi.org/10.1016/j.jep.2020.112953" @default.
• W3021136082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32407936" @default.
• W3021136082 hasPublicationYear "2020" @default.
• W3021136082 type Work @default.
• W3021136082 sameAs 3021136082 @default.
• W3021136082 citedByCount "14" @default.
• W3021136082 countsByYear W30211360822021 @default.
• W3021136082 countsByYear W30211360822022 @default.
• W3021136082 countsByYear W30211360822023 @default.
• W3021136082 crossrefType "journal-article" @default.
• W3021136082 hasAuthorship W3021136082A5007931200 @default.
• W3021136082 hasAuthorship W3021136082A5010599695 @default.
• W3021136082 hasAuthorship W3021136082A5042339155 @default.
• W3021136082 hasAuthorship W3021136082A5059484326 @default.
• W3021136082 hasAuthorship W3021136082A5065927898 @default.
• W3021136082 hasAuthorship W3021136082A5076846612 @default.
• W3021136082 hasAuthorship W3021136082A5080000178 @default.
• W3021136082 hasAuthorship W3021136082A5082857859 @default.
• W3021136082 hasConcept C192989942 @default.
• W3021136082 hasConcept C21565614 @default.
• W3021136082 hasConcept C2776357993 @default.
• W3021136082 hasConcept C2777735490 @default.
• W3021136082 hasConcept C2778168646 @default.
• W3021136082 hasConcept C2779399885 @default.
• W3021136082 hasConcept C501593827 @default.
• W3021136082 hasConcept C523546767 @default.
• W3021136082 hasConcept C539455810 @default.
• W3021136082 hasConcept C54355233 @default.
• W3021136082 hasConcept C55493867 @default.
• W3021136082 hasConcept C60644358 @default.
• W3021136082 hasConcept C62231903 @default.
• W3021136082 hasConcept C86803240 @default.
• W3021136082 hasConcept C89423630 @default.
• W3021136082 hasConceptScore W3021136082C192989942 @default.
• W3021136082 hasConceptScore W3021136082C21565614 @default.
• W3021136082 hasConceptScore W3021136082C2776357993 @default.
• W3021136082 hasConceptScore W3021136082C2777735490 @default.
• W3021136082 hasConceptScore W3021136082C2778168646 @default.
• W3021136082 hasConceptScore W3021136082C2779399885 @default.
• W3021136082 hasConceptScore W3021136082C501593827 @default.
• W3021136082 hasConceptScore W3021136082C523546767 @default.
• W3021136082 hasConceptScore W3021136082C539455810 @default.
• W3021136082 hasConceptScore W3021136082C54355233 @default.
• W3021136082 hasConceptScore W3021136082C55493867 @default.
• W3021136082 hasConceptScore W3021136082C60644358 @default.
• W3021136082 hasConceptScore W3021136082C62231903 @default.
• W3021136082 hasConceptScore W3021136082C86803240 @default.
• W3021136082 hasConceptScore W3021136082C89423630 @default.
• W3021136082 hasFunder F4320321001 @default.
• W3021136082 hasFunder F4320325068 @default.
• W3021136082 hasFunder F4320335480 @default.
• W3021136082 hasLocation W30211360821 @default.
• W3021136082 hasOpenAccess W3021136082 @default.
• W3021136082 hasPrimaryLocation W30211360821 @default.
• W3021136082 hasRelatedWork W1893585461 @default.
• W3021136082 hasRelatedWork W2003969178 @default.
• W3021136082 hasRelatedWork W2077172214 @default.

• next